Case Report: Late paradoxical intrapulmonary shunt after endoscopic lung volume reduction with endobronchial valves for severe emphysema
Endoscopic endobronchial valve lung volume reduction in the management of severe emphysema reduces volume inflation in the most severely affected areas, with the hope of clinical improvement. We report the case of a patient who presented with late progressive respiratory deterioration following endo...
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Frontiers Media S.A.
2025-05-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2025.1572900/full |
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| author | Jacques Dzuko Kamga Christophe Gut Gobert Christophe Gut Gobert Thomas Egenod Nicolas Guibert Pierre-Yves Le Roux Pierre-Yves Le Roux |
| author_facet | Jacques Dzuko Kamga Christophe Gut Gobert Christophe Gut Gobert Thomas Egenod Nicolas Guibert Pierre-Yves Le Roux Pierre-Yves Le Roux |
| author_sort | Jacques Dzuko Kamga |
| collection | DOAJ |
| description | Endoscopic endobronchial valve lung volume reduction in the management of severe emphysema reduces volume inflation in the most severely affected areas, with the hope of clinical improvement. We report the case of a patient who presented with late progressive respiratory deterioration following endoscopic endobronchial valve lung volume reduction. Ventilation/perfusion (V/Q)-SPECT/CT showed unexpectedly high perfusion in the atelectasis of the treated lobes, reflecting a paradoxical intrapulmonary shunt. This paradoxical complication of endobronchial valve treatment for severe emphysema is rare and highlights the potential usefulness of performing V/Q-SPECT/CT imaging in patients presenting with respiratory deterioration following endoscopic lung volume reduction. |
| format | Article |
| id | doaj-art-e44b481edb0549af87da411408ca6950 |
| institution | OA Journals |
| issn | 2296-858X |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj-art-e44b481edb0549af87da411408ca69502025-08-20T01:49:58ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2025-05-011210.3389/fmed.2025.15729001572900Case Report: Late paradoxical intrapulmonary shunt after endoscopic lung volume reduction with endobronchial valves for severe emphysemaJacques Dzuko Kamga0Christophe Gut Gobert1Christophe Gut Gobert2Thomas Egenod3Nicolas Guibert4Pierre-Yves Le Roux5Pierre-Yves Le Roux6Department of Nuclear Medicine, Brest University Hospital, Brest, FranceDepartment of Pneumology, Brest University Hospital, Brest, FranceGETBO, INSERM, UMR1304, Université de Bretagne Occidentale, Brest, FranceDepartment of Pneumology, Limoges University Hospital, Limoges, FranceDepartment of Pneumology, Toulouse University Hospital, Toulouse, FranceDepartment of Nuclear Medicine, Brest University Hospital, Brest, FranceGETBO, INSERM, UMR1304, Université de Bretagne Occidentale, Brest, FranceEndoscopic endobronchial valve lung volume reduction in the management of severe emphysema reduces volume inflation in the most severely affected areas, with the hope of clinical improvement. We report the case of a patient who presented with late progressive respiratory deterioration following endoscopic endobronchial valve lung volume reduction. Ventilation/perfusion (V/Q)-SPECT/CT showed unexpectedly high perfusion in the atelectasis of the treated lobes, reflecting a paradoxical intrapulmonary shunt. This paradoxical complication of endobronchial valve treatment for severe emphysema is rare and highlights the potential usefulness of performing V/Q-SPECT/CT imaging in patients presenting with respiratory deterioration following endoscopic lung volume reduction.https://www.frontiersin.org/articles/10.3389/fmed.2025.1572900/fullendo-bronchial valvesendoscopic lung volume reduction (ELVR)emphysemaventilation-perfusion SPECT–CTlung scintigraphypulmonary shunt |
| spellingShingle | Jacques Dzuko Kamga Christophe Gut Gobert Christophe Gut Gobert Thomas Egenod Nicolas Guibert Pierre-Yves Le Roux Pierre-Yves Le Roux Case Report: Late paradoxical intrapulmonary shunt after endoscopic lung volume reduction with endobronchial valves for severe emphysema Frontiers in Medicine endo-bronchial valves endoscopic lung volume reduction (ELVR) emphysema ventilation-perfusion SPECT–CT lung scintigraphy pulmonary shunt |
| title | Case Report: Late paradoxical intrapulmonary shunt after endoscopic lung volume reduction with endobronchial valves for severe emphysema |
| title_full | Case Report: Late paradoxical intrapulmonary shunt after endoscopic lung volume reduction with endobronchial valves for severe emphysema |
| title_fullStr | Case Report: Late paradoxical intrapulmonary shunt after endoscopic lung volume reduction with endobronchial valves for severe emphysema |
| title_full_unstemmed | Case Report: Late paradoxical intrapulmonary shunt after endoscopic lung volume reduction with endobronchial valves for severe emphysema |
| title_short | Case Report: Late paradoxical intrapulmonary shunt after endoscopic lung volume reduction with endobronchial valves for severe emphysema |
| title_sort | case report late paradoxical intrapulmonary shunt after endoscopic lung volume reduction with endobronchial valves for severe emphysema |
| topic | endo-bronchial valves endoscopic lung volume reduction (ELVR) emphysema ventilation-perfusion SPECT–CT lung scintigraphy pulmonary shunt |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2025.1572900/full |
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