Unilateral polyorchidism with severe male infertility: a case report

Abstract Polyorchidism is an uncommon congenital condition often discovered incidentally, which may significantly impact male fertility. We present a case of a 34-year-old man with unilateral polyorchidism and associated severe asthenozoospermia and teratozoospermia. Despite normal hormonal levels a...

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Main Authors: Fang Yang, Jingyi Zhang, Yao Xiao, Shiyun Pu, Meijing Wang, Shengxi Xiong, Xinyi Tang, Xujun Yu, Degui Chang
Format: Article
Language:English
Published: BMC 2024-10-01
Series:BMC Urology
Subjects:
Online Access:https://doi.org/10.1186/s12894-024-01626-1
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author Fang Yang
Jingyi Zhang
Yao Xiao
Shiyun Pu
Meijing Wang
Shengxi Xiong
Xinyi Tang
Xujun Yu
Degui Chang
author_facet Fang Yang
Jingyi Zhang
Yao Xiao
Shiyun Pu
Meijing Wang
Shengxi Xiong
Xinyi Tang
Xujun Yu
Degui Chang
author_sort Fang Yang
collection DOAJ
description Abstract Polyorchidism is an uncommon congenital condition often discovered incidentally, which may significantly impact male fertility. We present a case of a 34-year-old man with unilateral polyorchidism and associated severe asthenozoospermia and teratozoospermia. Despite normal hormonal levels and no detected genetic anomalies, the patient’s sperm showed mitochondrial damage, and his fertility remained compromised after conservative management and assisted reproductive attempts. This case underscores the intricate relationship between polyorchidism and male infertility, highlighting the need for personalized management strategies and further research into its etiology and impact.
format Article
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institution OA Journals
issn 1471-2490
language English
publishDate 2024-10-01
publisher BMC
record_format Article
series BMC Urology
spelling doaj-art-e44675d26b954fe8a836f7027069ad442025-08-20T02:17:53ZengBMCBMC Urology1471-24902024-10-012411610.1186/s12894-024-01626-1Unilateral polyorchidism with severe male infertility: a case reportFang Yang0Jingyi Zhang1Yao Xiao2Shiyun Pu3Meijing Wang4Shengxi Xiong5Xinyi Tang6Xujun Yu7Degui Chang8TCM Regulating Metabolic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese MedicineTCM Regulating Metabolic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese MedicineTCM Regulating Metabolic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese MedicineChengdu Fifth People’s Hospital, The Second Clinical Medical College, Affiliated Fifth People’s Hospital of Chengdu University of Traditional Chinese MedicineTCM Regulating Metabolic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese MedicineTCM Regulating Metabolic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese MedicineTCM Regulating Metabolic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese MedicineTCM Regulating Metabolic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese MedicineTCM Regulating Metabolic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese MedicineAbstract Polyorchidism is an uncommon congenital condition often discovered incidentally, which may significantly impact male fertility. We present a case of a 34-year-old man with unilateral polyorchidism and associated severe asthenozoospermia and teratozoospermia. Despite normal hormonal levels and no detected genetic anomalies, the patient’s sperm showed mitochondrial damage, and his fertility remained compromised after conservative management and assisted reproductive attempts. This case underscores the intricate relationship between polyorchidism and male infertility, highlighting the need for personalized management strategies and further research into its etiology and impact.https://doi.org/10.1186/s12894-024-01626-1PolyorchidismMale infertilityAsthenozoospermiaTeratozoospermiaMitochondrial damageSemen analysis
spellingShingle Fang Yang
Jingyi Zhang
Yao Xiao
Shiyun Pu
Meijing Wang
Shengxi Xiong
Xinyi Tang
Xujun Yu
Degui Chang
Unilateral polyorchidism with severe male infertility: a case report
BMC Urology
Polyorchidism
Male infertility
Asthenozoospermia
Teratozoospermia
Mitochondrial damage
Semen analysis
title Unilateral polyorchidism with severe male infertility: a case report
title_full Unilateral polyorchidism with severe male infertility: a case report
title_fullStr Unilateral polyorchidism with severe male infertility: a case report
title_full_unstemmed Unilateral polyorchidism with severe male infertility: a case report
title_short Unilateral polyorchidism with severe male infertility: a case report
title_sort unilateral polyorchidism with severe male infertility a case report
topic Polyorchidism
Male infertility
Asthenozoospermia
Teratozoospermia
Mitochondrial damage
Semen analysis
url https://doi.org/10.1186/s12894-024-01626-1
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AT shiyunpu unilateralpolyorchidismwithseveremaleinfertilityacasereport
AT meijingwang unilateralpolyorchidismwithseveremaleinfertilityacasereport
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