Syntheses, Characterization and Biological Activity of Some 1, 2, 4-Triazole Derivatives
Syntheses of a series of 3-alkyl-4- amino-5- cyanomethyl-4H-1, 2, 4-triazoles with active methylene groups are described. The newly synthesized compounds were characterized by spectral and elemental analyses. Some compounds were screened for their antibacterial activity against S. aureus, E. coli, B...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2009-01-01
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| Series: | E-Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2009/419214 |
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| Summary: | Syntheses of a series of 3-alkyl-4- amino-5- cyanomethyl-4H-1, 2, 4-triazoles with active methylene groups are described. The newly synthesized compounds were characterized by spectral and elemental analyses. Some compounds were screened for their antibacterial activity against S. aureus, E. coli, B. subtilis and P. aeruginosa. All the compounds carrying 1, 2, 4- triazole moiety showed significant biological activity. |
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| ISSN: | 0973-4945 2090-9810 |