De Quervain’s Tenosynovitis Virally Exacerbated by SARS-CoV-2 and Influenza Infections: A Case Report

We present the case of a fully vaccinated 39-year-old male with no pertinent past medical history who initially presented with De Quervain’s tenosynovitis which was successfully treated with a corticosteroid injection. His symptoms recurred during a COVID-19 infection, which was treated with a repea...

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Main Authors: Maria Gergoudis, Logan Laubach, Glenn E. Lee, Jeffrey R. Donowitz
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Case Reports in Infectious Diseases
Online Access:http://dx.doi.org/10.1155/crdi/5117572
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author Maria Gergoudis
Logan Laubach
Glenn E. Lee
Jeffrey R. Donowitz
author_facet Maria Gergoudis
Logan Laubach
Glenn E. Lee
Jeffrey R. Donowitz
author_sort Maria Gergoudis
collection DOAJ
description We present the case of a fully vaccinated 39-year-old male with no pertinent past medical history who initially presented with De Quervain’s tenosynovitis which was successfully treated with a corticosteroid injection. His symptoms recurred during a COVID-19 infection, which was treated with a repeat corticosteroid injection. Symptoms recurred during an influenza infection and were subsequently treated with a first dorsal compartment release. The etiology of De Quervain’s tenosynovitis remains unclear. It has classically been categorized as a noninflammatory degenerative process, but recent evidence suggests a possible inflammatory connection. Here, we present a case of recurrent De Quervain’s tenosynovitis exacerbated by two distinct viral infections. We hypothesize that viral-induced systemic inflammation led to localized recurrence of inflammation within the tendon sheath. Further studies including cytokine analysis and inflammatory markers are needed to advance this hypothesis.
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institution Kabale University
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series Case Reports in Infectious Diseases
spelling doaj-art-e43dc14c486940c29e9aaf059c50b31c2025-01-26T00:00:02ZengWileyCase Reports in Infectious Diseases2090-66332025-01-01202510.1155/crdi/5117572De Quervain’s Tenosynovitis Virally Exacerbated by SARS-CoV-2 and Influenza Infections: A Case ReportMaria Gergoudis0Logan Laubach1Glenn E. Lee2Jeffrey R. Donowitz3Department of Orthopaedic SurgeryDepartment of Orthopaedic SurgeryDepartment of Orthopaedic SurgeryDivision of Pediatric Infectious DiseasesWe present the case of a fully vaccinated 39-year-old male with no pertinent past medical history who initially presented with De Quervain’s tenosynovitis which was successfully treated with a corticosteroid injection. His symptoms recurred during a COVID-19 infection, which was treated with a repeat corticosteroid injection. Symptoms recurred during an influenza infection and were subsequently treated with a first dorsal compartment release. The etiology of De Quervain’s tenosynovitis remains unclear. It has classically been categorized as a noninflammatory degenerative process, but recent evidence suggests a possible inflammatory connection. Here, we present a case of recurrent De Quervain’s tenosynovitis exacerbated by two distinct viral infections. We hypothesize that viral-induced systemic inflammation led to localized recurrence of inflammation within the tendon sheath. Further studies including cytokine analysis and inflammatory markers are needed to advance this hypothesis.http://dx.doi.org/10.1155/crdi/5117572
spellingShingle Maria Gergoudis
Logan Laubach
Glenn E. Lee
Jeffrey R. Donowitz
De Quervain’s Tenosynovitis Virally Exacerbated by SARS-CoV-2 and Influenza Infections: A Case Report
Case Reports in Infectious Diseases
title De Quervain’s Tenosynovitis Virally Exacerbated by SARS-CoV-2 and Influenza Infections: A Case Report
title_full De Quervain’s Tenosynovitis Virally Exacerbated by SARS-CoV-2 and Influenza Infections: A Case Report
title_fullStr De Quervain’s Tenosynovitis Virally Exacerbated by SARS-CoV-2 and Influenza Infections: A Case Report
title_full_unstemmed De Quervain’s Tenosynovitis Virally Exacerbated by SARS-CoV-2 and Influenza Infections: A Case Report
title_short De Quervain’s Tenosynovitis Virally Exacerbated by SARS-CoV-2 and Influenza Infections: A Case Report
title_sort de quervain s tenosynovitis virally exacerbated by sars cov 2 and influenza infections a case report
url http://dx.doi.org/10.1155/crdi/5117572
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