From Chilean saltpeter to modern agriculture: navigating nitrate toxicity in ruminants through compartmental modeling
Nitrate/nitrite poisoning is a significant issue in ruminant livestock health, with historical roots predating the widespread use of nitrogen fertilizers. This review explores the various factors contributing to nitrate toxicity, including natural and anthropogenic sources, metabolic pathways, mecha...
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| Format: | Article |
| Language: | English |
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Institute of Animal Biology NAAS
2024-07-01
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| Series: | Біологія тварин |
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| Online Access: | https://aminbiol.com.ua/index.php/archive/206-archive/bt-26-2-2024/2141-from-chilean-saltpeter-to-modern-agriculture-navigating-nitrate-toxicity-in-ruminants-through-compartmental-modeling |
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| _version_ | 1850178958559019008 |
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| author | I. Ya. Oliynyk |
| author_facet | I. Ya. Oliynyk |
| author_sort | I. Ya. Oliynyk |
| collection | DOAJ |
| description | Nitrate/nitrite poisoning is a significant issue in ruminant livestock health, with historical roots predating the widespread use of nitrogen fertilizers. This review explores the various factors contributing to nitrate toxicity, including natural and anthropogenic sources, metabolic pathways, mechanisms of action, and the variability in reported data. The importance of compartmental modeling in understanding nitrate metabolism dynamics is emphasized. These models provide a framework for simulating the complex processes involved in nitrate intake, conversion, absorption, distribution, and excretion, ultimately informing effective mitigation strategies. The goal of this article is to provide a comprehensive overview of nitrate/nitrite poisoning in ruminants and highlight the role of compartmental modeling in safeguarding animal health, optimizing agricultural practices, and ensuring food safety in the context of modern agriculture. |
| format | Article |
| id | doaj-art-e43a249f52af4f3aaab576de748d8aa2 |
| institution | OA Journals |
| issn | 1681-0015 2313-2191 |
| language | English |
| publishDate | 2024-07-01 |
| publisher | Institute of Animal Biology NAAS |
| record_format | Article |
| series | Біологія тварин |
| spelling | doaj-art-e43a249f52af4f3aaab576de748d8aa22025-08-20T02:18:36ZengInstitute of Animal Biology NAASБіологія тварин1681-00152313-21912024-07-01262111810.15407/animbiol26.02.011From Chilean saltpeter to modern agriculture: navigating nitrate toxicity in ruminants through compartmental modelingI. Ya. Oliynyk0https://orcid.org/0000-0003-2487-1022Institute of Animal Biology NAASNitrate/nitrite poisoning is a significant issue in ruminant livestock health, with historical roots predating the widespread use of nitrogen fertilizers. This review explores the various factors contributing to nitrate toxicity, including natural and anthropogenic sources, metabolic pathways, mechanisms of action, and the variability in reported data. The importance of compartmental modeling in understanding nitrate metabolism dynamics is emphasized. These models provide a framework for simulating the complex processes involved in nitrate intake, conversion, absorption, distribution, and excretion, ultimately informing effective mitigation strategies. The goal of this article is to provide a comprehensive overview of nitrate/nitrite poisoning in ruminants and highlight the role of compartmental modeling in safeguarding animal health, optimizing agricultural practices, and ensuring food safety in the context of modern agriculture.https://aminbiol.com.ua/index.php/archive/206-archive/bt-26-2-2024/2141-from-chilean-saltpeter-to-modern-agriculture-navigating-nitrate-toxicity-in-ruminants-through-compartmental-modelingnitrate toxicityruminantscompartmental modelingmethemoglobinemiafeed managementнітратна токсичністьжуйні твариникомпартментальне моделюванняметгемоглобінеміяуправління кормами |
| spellingShingle | I. Ya. Oliynyk From Chilean saltpeter to modern agriculture: navigating nitrate toxicity in ruminants through compartmental modeling Біологія тварин nitrate toxicity ruminants compartmental modeling methemoglobinemia feed management нітратна токсичність жуйні тварини компартментальне моделювання метгемоглобінемія управління кормами |
| title | From Chilean saltpeter to modern agriculture: navigating nitrate toxicity in ruminants through compartmental modeling |
| title_full | From Chilean saltpeter to modern agriculture: navigating nitrate toxicity in ruminants through compartmental modeling |
| title_fullStr | From Chilean saltpeter to modern agriculture: navigating nitrate toxicity in ruminants through compartmental modeling |
| title_full_unstemmed | From Chilean saltpeter to modern agriculture: navigating nitrate toxicity in ruminants through compartmental modeling |
| title_short | From Chilean saltpeter to modern agriculture: navigating nitrate toxicity in ruminants through compartmental modeling |
| title_sort | from chilean saltpeter to modern agriculture navigating nitrate toxicity in ruminants through compartmental modeling |
| topic | nitrate toxicity ruminants compartmental modeling methemoglobinemia feed management нітратна токсичність жуйні тварини компартментальне моделювання метгемоглобінемія управління кормами |
| url | https://aminbiol.com.ua/index.php/archive/206-archive/bt-26-2-2024/2141-from-chilean-saltpeter-to-modern-agriculture-navigating-nitrate-toxicity-in-ruminants-through-compartmental-modeling |
| work_keys_str_mv | AT iyaoliynyk fromchileansaltpetertomodernagriculturenavigatingnitratetoxicityinruminantsthroughcompartmentalmodeling |