The Degenerating Substantia Nigra as a Susceptible Region for Gene Transfer-Mediated Inflammation

The Degenerating Substantia Nigra as a Susceptible Region for Gene Transfer-Mediated Inflammation

Parkinson's disease (PD) is characterized by the progressive degeneration of neurons in the substantia nigra pars compacta (SN). The naïve SN is highly susceptible to inflammation. In addition, microglial activation in the degenerating SN displays distinct characteristics that increase the reac...

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Bibliographic Details
Main Authors: Valeria Roca, Juan Cruz Casabona, Pablo Radice, Verónica Murta, Fernando Juan Pitossi
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Parkinson's Disease
Online Access:http://dx.doi.org/10.4061/2011/931572
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