Dual roles of exostosin glycosyltransferase 1 in Zika virus infection

Dual roles of exostosin glycosyltransferase 1 in Zika virus infection

Many factors involved in heparan sulfate (HS) biosynthesis and metabolism have been reported to play roles in viral infection. However, the detailed mechanisms are still not fully understood. In this study, we report that exostosin glycosyltransferase 1 (EXT1), the HS polymerase, is a critical regul...

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Bibliographic Details
Main Authors: Jiaxin Ling, Asifa Khan, Matthias Denkewitz, Marco Maccarana, Åke Lundkvist, Jin-Ping Li, Jinlin Li
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Virulence
Subjects:
ZIKV
EXT1
heparan sulfate
autophagy
Online Access:https://www.tandfonline.com/doi/10.1080/21505594.2025.2458681
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