Cryo-EM structure and oligomerization of the human planar cell polarity core protein Vangl1
Abstract Vangl is a planar cell polarity (PCP) core protein essential for aligned cell orientation along the epithelial plane perpendicular to the apical-basal direction, which is important for tissue morphogenesis, development and collective cell behavior. Mutations in Vangl are associated with dev...
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| Main Authors: | Fan Zhang, Shaobai Li, Hao Wu, Shanshuang Chen |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-01-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-024-55397-2 |
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