Case Report: An azygos vein aneurysm with dysphagia assisted diagnosis by esophageal endoscopic ultrasonography

BackgroundAzygos vein aneurysm (AVA) is a rare thoracic pathology that is frequently misdiagnosed. While contrast-enhanced chest computed tomography (CT) or magnetic resonance imaging (MRI) can delineate AVA location and size, these techniques lack the capability for dynamic real-time assessment of...

Full description

Saved in:
Bibliographic Details
Main Authors: Xueyan Guo, Yuanhang Xu, Yanfei Cao, Yan Jin
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1516064/full
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849229414591627264
author Xueyan Guo
Yuanhang Xu
Yanfei Cao
Yan Jin
author_facet Xueyan Guo
Yuanhang Xu
Yanfei Cao
Yan Jin
author_sort Xueyan Guo
collection DOAJ
description BackgroundAzygos vein aneurysm (AVA) is a rare thoracic pathology that is frequently misdiagnosed. While contrast-enhanced chest computed tomography (CT) or magnetic resonance imaging (MRI) can delineate AVA location and size, these techniques lack the capability for dynamic real-time assessment of internal architecture.Case presentationWe present a highly unusual case of a 67-year-old woman who had an isolated azygos vein aneurysm presenting with dysphagia. The mass was first found by a chest X-ray. Subsequent contrast-enhanced chest CT revealed a 3.5 × 3.74 × 1.4 cm soft-tissue mass in the posterior mediastinum, suggestive of a lymph node. In contrast, esophageal endoscopic ultrasonography (EUS) demonstrated intact esophageal mucosa with extrinsic stenosis. The dynamic observation through EUS displayed that the mass was not a lymph node but a solitary cystic lesion with no internal blood flow, and there was no communication between the posterior azygos vein and the aorta. We considered that the dysphagia was caused by the cystic lesion. Thoracoscopic surgery was finally performed, which confirmed the mass as an AVA through pathological analysis.ConclusionsEUS is one of the most effective and vital tools for the preoperative evaluation of AVA.
format Article
id doaj-art-e427d861bdb14bb998560f80b1f63475
institution Kabale University
issn 2234-943X
language English
publishDate 2025-08-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Oncology
spelling doaj-art-e427d861bdb14bb998560f80b1f634752025-08-22T04:10:40ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2025-08-011510.3389/fonc.2025.15160641516064Case Report: An azygos vein aneurysm with dysphagia assisted diagnosis by esophageal endoscopic ultrasonographyXueyan Guo0Yuanhang Xu1Yanfei Cao2Yan Jin3Department of Gastroenterology, Shaanxi Provincial People’s Hospital, Xi’an, ChinaDepartment of Gastroenterology, Shaanxi Provincial People’s Hospital, Xi’an, ChinaDepartment of Thoracic Surgery, Shaanxi Provincial People’s Hospital, Xi’an, ChinaDepartment of Gastroenterology, Shaanxi Provincial People’s Hospital, Xi’an, ChinaBackgroundAzygos vein aneurysm (AVA) is a rare thoracic pathology that is frequently misdiagnosed. While contrast-enhanced chest computed tomography (CT) or magnetic resonance imaging (MRI) can delineate AVA location and size, these techniques lack the capability for dynamic real-time assessment of internal architecture.Case presentationWe present a highly unusual case of a 67-year-old woman who had an isolated azygos vein aneurysm presenting with dysphagia. The mass was first found by a chest X-ray. Subsequent contrast-enhanced chest CT revealed a 3.5 × 3.74 × 1.4 cm soft-tissue mass in the posterior mediastinum, suggestive of a lymph node. In contrast, esophageal endoscopic ultrasonography (EUS) demonstrated intact esophageal mucosa with extrinsic stenosis. The dynamic observation through EUS displayed that the mass was not a lymph node but a solitary cystic lesion with no internal blood flow, and there was no communication between the posterior azygos vein and the aorta. We considered that the dysphagia was caused by the cystic lesion. Thoracoscopic surgery was finally performed, which confirmed the mass as an AVA through pathological analysis.ConclusionsEUS is one of the most effective and vital tools for the preoperative evaluation of AVA.https://www.frontiersin.org/articles/10.3389/fonc.2025.1516064/fulldysphagiaAVAmediastinal masscystic lesionEUS
spellingShingle Xueyan Guo
Yuanhang Xu
Yanfei Cao
Yan Jin
Case Report: An azygos vein aneurysm with dysphagia assisted diagnosis by esophageal endoscopic ultrasonography
Frontiers in Oncology
dysphagia
AVA
mediastinal mass
cystic lesion
EUS
title Case Report: An azygos vein aneurysm with dysphagia assisted diagnosis by esophageal endoscopic ultrasonography
title_full Case Report: An azygos vein aneurysm with dysphagia assisted diagnosis by esophageal endoscopic ultrasonography
title_fullStr Case Report: An azygos vein aneurysm with dysphagia assisted diagnosis by esophageal endoscopic ultrasonography
title_full_unstemmed Case Report: An azygos vein aneurysm with dysphagia assisted diagnosis by esophageal endoscopic ultrasonography
title_short Case Report: An azygos vein aneurysm with dysphagia assisted diagnosis by esophageal endoscopic ultrasonography
title_sort case report an azygos vein aneurysm with dysphagia assisted diagnosis by esophageal endoscopic ultrasonography
topic dysphagia
AVA
mediastinal mass
cystic lesion
EUS
url https://www.frontiersin.org/articles/10.3389/fonc.2025.1516064/full
work_keys_str_mv AT xueyanguo casereportanazygosveinaneurysmwithdysphagiaassisteddiagnosisbyesophagealendoscopicultrasonography
AT yuanhangxu casereportanazygosveinaneurysmwithdysphagiaassisteddiagnosisbyesophagealendoscopicultrasonography
AT yanfeicao casereportanazygosveinaneurysmwithdysphagiaassisteddiagnosisbyesophagealendoscopicultrasonography
AT yanjin casereportanazygosveinaneurysmwithdysphagiaassisteddiagnosisbyesophagealendoscopicultrasonography