Iron Homeostasis as a Mediator Linking Central Obesity with MASLD and Primary Liver Cancer: A Two-Step Mendelian Randomization Study

Iron Homeostasis as a Mediator Linking Central Obesity with MASLD and Primary Liver Cancer: A Two-Step Mendelian Randomization Study

<b>Objectives</b>: This study aimed to explore the mediating effects of iron homeostasis biomarkers linking central obesity with metabolic dysfunction-associated steatotic liver disease (MASLD) and primary liver cancer (PLC) via Mendelian randomization (MR) analysis. <b>Methods<...

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Bibliographic Details
Main Authors: Yuping Zeng, Xia Wang, Shenlin Liao, Chuan Li, Jie Chen, He He
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Biomedicines
Subjects:
central obesity
ferritin
Mendelian randomization
causality
Online Access:https://www.mdpi.com/2227-9059/13/7/1641
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