Differences in clinical and endocrine features between obese and non-obese women in polycystic ovarian syndrome
Background and objectives: The polycystic ovary syndrome is one of the commonest endocrine disturbance affecting 5-8% of reproductive age women. It is a heterogenous disorder that mainly presents with features of hyperandro- genism and anovulation. These clinical features are further affected by bo...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Kurdistan Higher Council Of Medical Specialties
2023-02-01
|
| Series: | Advanced Medical Journal |
| Subjects: | |
| Online Access: | https://amj.khcms.edu.krd/index.php/main/article/view/124 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850202339985588224 |
|---|---|
| author | Awat Ibrahim Hamadamen Zhyan Baker Hasan Jalal Abdullah Hasan Albazaz Rebaz Tahir Lak |
| author_facet | Awat Ibrahim Hamadamen Zhyan Baker Hasan Jalal Abdullah Hasan Albazaz Rebaz Tahir Lak |
| author_sort | Awat Ibrahim Hamadamen |
| collection | DOAJ |
| description |
Background and objectives: The polycystic ovary syndrome is one of the commonest endocrine disturbance affecting 5-8% of reproductive age women. It is a heterogenous disorder that mainly presents with features of hyperandro- genism and anovulation. These clinical features are further affected by body mass index at presentation. This study aimed to estimate the impact of obesity on the clinical features of polycystic ovary syndrome and to compare hor- monal and ultrasonography features between obese and non-obese polycystic ovary syndrome women.
Methods: a cross-sectional comparative study carried on 230 infertile women with criteria of polycystic ovary syndrome attend- ing Private Hawler Centre for Infertility and in vitro fertilization, Erbil, Iraq, in the period between the 1st of October 2015 and the 1st of April 2016.
Results: Out of 230 polycystic ovarian syndrome women, the BMI was 25 kg/m2 in 123 ladies (53.48%); 32 ladies 13.9% were overweight and 91 ladies 39.5% were obese. Obese polycystic ovary syndrome women had more sedentary life, more family history of polycystic ovary syndrome and associated with higher miscarriage rate. Amenorrhea and oligomenorrhoea were found more frequently in obese women 24.4% and 62.6% respectively than non-obese polycystic ovary syndrome women 21.5% and 53.3%.
Conclusions: Obesity has a significant impact on the appearance of clinical features of polycystic ovary syndrome among infertile women, signs of hyperandrogenism, maximum ovarian volume and mean serum level of hormones including luteinizing hormone, progesterone and testosterone were significantly more reported in obese than non-obese polycystic ovary syndrome women.
|
| format | Article |
| id | doaj-art-e423905fab9f4b86927e54792528c0e9 |
| institution | OA Journals |
| issn | 2958-8979 2957-3580 |
| language | English |
| publishDate | 2023-02-01 |
| publisher | Kurdistan Higher Council Of Medical Specialties |
| record_format | Article |
| series | Advanced Medical Journal |
| spelling | doaj-art-e423905fab9f4b86927e54792528c0e92025-08-20T02:11:47ZengKurdistan Higher Council Of Medical SpecialtiesAdvanced Medical Journal2958-89792957-35802023-02-013110.56056/amj.2017.23125Differences in clinical and endocrine features between obese and non-obese women in polycystic ovarian syndromeAwat Ibrahim Hamadamen0Zhyan Baker Hasan1Jalal Abdullah Hasan Albazaz2Rebaz Tahir Lak3Lecturer, College of medicine\OBGYN departmentPrivate Hawler Center for Infertility and IVFDiagnostic Radiologist, Erbil Teaching HospitalLecturer, Kurdistan Board of Medical Specialties, Planning Department. Erbil-Iraq Background and objectives: The polycystic ovary syndrome is one of the commonest endocrine disturbance affecting 5-8% of reproductive age women. It is a heterogenous disorder that mainly presents with features of hyperandro- genism and anovulation. These clinical features are further affected by body mass index at presentation. This study aimed to estimate the impact of obesity on the clinical features of polycystic ovary syndrome and to compare hor- monal and ultrasonography features between obese and non-obese polycystic ovary syndrome women. Methods: a cross-sectional comparative study carried on 230 infertile women with criteria of polycystic ovary syndrome attend- ing Private Hawler Centre for Infertility and in vitro fertilization, Erbil, Iraq, in the period between the 1st of October 2015 and the 1st of April 2016. Results: Out of 230 polycystic ovarian syndrome women, the BMI was 25 kg/m2 in 123 ladies (53.48%); 32 ladies 13.9% were overweight and 91 ladies 39.5% were obese. Obese polycystic ovary syndrome women had more sedentary life, more family history of polycystic ovary syndrome and associated with higher miscarriage rate. Amenorrhea and oligomenorrhoea were found more frequently in obese women 24.4% and 62.6% respectively than non-obese polycystic ovary syndrome women 21.5% and 53.3%. Conclusions: Obesity has a significant impact on the appearance of clinical features of polycystic ovary syndrome among infertile women, signs of hyperandrogenism, maximum ovarian volume and mean serum level of hormones including luteinizing hormone, progesterone and testosterone were significantly more reported in obese than non-obese polycystic ovary syndrome women. https://amj.khcms.edu.krd/index.php/main/article/view/124Amenorrheahirsutismobesitypolycystic ovarian syndrome |
| spellingShingle | Awat Ibrahim Hamadamen Zhyan Baker Hasan Jalal Abdullah Hasan Albazaz Rebaz Tahir Lak Differences in clinical and endocrine features between obese and non-obese women in polycystic ovarian syndrome Advanced Medical Journal Amenorrhea hirsutism obesity polycystic ovarian syndrome |
| title | Differences in clinical and endocrine features between obese and non-obese women in polycystic ovarian syndrome |
| title_full | Differences in clinical and endocrine features between obese and non-obese women in polycystic ovarian syndrome |
| title_fullStr | Differences in clinical and endocrine features between obese and non-obese women in polycystic ovarian syndrome |
| title_full_unstemmed | Differences in clinical and endocrine features between obese and non-obese women in polycystic ovarian syndrome |
| title_short | Differences in clinical and endocrine features between obese and non-obese women in polycystic ovarian syndrome |
| title_sort | differences in clinical and endocrine features between obese and non obese women in polycystic ovarian syndrome |
| topic | Amenorrhea hirsutism obesity polycystic ovarian syndrome |
| url | https://amj.khcms.edu.krd/index.php/main/article/view/124 |
| work_keys_str_mv | AT awatibrahimhamadamen differencesinclinicalandendocrinefeaturesbetweenobeseandnonobesewomeninpolycysticovariansyndrome AT zhyanbakerhasan differencesinclinicalandendocrinefeaturesbetweenobeseandnonobesewomeninpolycysticovariansyndrome AT jalalabdullahhasanalbazaz differencesinclinicalandendocrinefeaturesbetweenobeseandnonobesewomeninpolycysticovariansyndrome AT rebaztahirlak differencesinclinicalandendocrinefeaturesbetweenobeseandnonobesewomeninpolycysticovariansyndrome |