Kaempferol protects against doxorubicin-induced myocardial damage by inhibiting mitochondrial ROS-dependent ferroptosis

Kaempferol protects against doxorubicin-induced myocardial damage by inhibiting mitochondrial ROS-dependent ferroptosis

Background Doxorubicin (DOX), a widely used chemotherapeutic agent, is limited in clinical application due to its dose-dependent cardiotoxicity. Therefore, it is crucial to explore alternative therapeutic molecules or drugs for mitigating DOX-induced cardiomyopathy (DIC). In this study aimed to expl...

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Bibliographic Details
Main Authors: Lin Zhang, Xiaorui Liu, Juan Wang, Zimu Li, Siqi Wang, Wen Yang, Yang Hai, Dongling Liu
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Redox Report
Subjects:
KP
DOX
cardiotoxicity
cardiomyocytes
mitochondrial ROS
ferroptosis
Online Access:https://www.tandfonline.com/doi/10.1080/13510002.2025.2503130
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