Cut‐Off Points for Low Relative 30‐s Sit‐to‐Stand Power and Their Associations With Adverse Health Conditions
ABSTRACT Background Despite muscle power derived from the 5‐rep sit‐to‐stand (STS) test having been demonstrated to be a valuable biomarker in older individuals, there is limited information regarding muscle power derived from the 30‐s STS test, a widely used test in the clinical setting. This study...
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| Format: | Article |
| Language: | English |
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Wiley
2025-02-01
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| Series: | Journal of Cachexia, Sarcopenia and Muscle |
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| Online Access: | https://doi.org/10.1002/jcsm.13676 |
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| author | Mikel Garcia‐Aguirre Ivan Baltasar‐Fernandez Julian Alcazar Jose Losa‐Reyna Ana Alfaro‐Acha Ignacio Ara Leocadio Rodriguez‐Mañas Luis M. Alegre Francisco J. Garcia‐Garcia |
| author_facet | Mikel Garcia‐Aguirre Ivan Baltasar‐Fernandez Julian Alcazar Jose Losa‐Reyna Ana Alfaro‐Acha Ignacio Ara Leocadio Rodriguez‐Mañas Luis M. Alegre Francisco J. Garcia‐Garcia |
| author_sort | Mikel Garcia‐Aguirre |
| collection | DOAJ |
| description | ABSTRACT Background Despite muscle power derived from the 5‐rep sit‐to‐stand (STS) test having been demonstrated to be a valuable biomarker in older individuals, there is limited information regarding muscle power derived from the 30‐s STS test, a widely used test in the clinical setting. This study aimed (i) to compare relative 30‐s STS power values between older men and women, (ii) to identify cut‐off points for low relative 30‐s STS power, (iii) to compare the prevalence of low relative STS power between sexes and (iv) to evaluate the association of low relative 30‐s STS power with adverse conditions in older people. Methods A total of 1475 community‐dwelling older adults (65–98 years; 45% men) from the Toledo Study for Healthy Aging were included. Relative STS power was assessed using the 30‐s STS test and the Alcazar's equation. Adverse health conditions considered encompassed frailty, depression, disability in basic (BADL) and instrumental activities of daily living (IADL), cognitive impairment and low habitual gait speed (HGS). Results Relative STS power decreased linearly at an average rate of 1.0% year−1 in men and 1.5% year−1 in women. The cut‐off points for low relative STS power were 2.53 and 2.01 W·kg−1 for men and women, respectively. The prevalence of low relative STS power was significantly lower in older men compared with older women (43.5% vs. 50.0%, respectively; p = 0.005). In men, low relative STS power was associated with frailty (OR [95% CI] = 4.4 [2.4–8.0]), cognitive impairment (OR [95% CI] = 1.7 [1.0–2.7]), disability in BADL (OR [95% CI] = 4.5 [1.5–13.8]) and low HGS (OR [95% CI] = 3.4 [1.9–5.9]). In women, low relative STS power was associated with frailty (OR [95% CI] = 5.2 [3.5–7.7]), disability in BADL (OR [95% CI] = 4.3 [1.8–9.9]) and IADL (OR [95% CI] = 3.1 [2.2–4.3]) and low HGS (OR [95% CI] = 6.1 [2.8–13.1]). No associations were found between low relative STS power and disability in IADL or depression in men, nor between low relative STS power and cognitive impairment or depression in women. Conclusion Relative STS power decreased with increasing age in both men and women. The provided sex‐specific cut‐off points for low relative STS power using the 30‐s STS test adequately identified older people with frailty and were associated with an increased risk of experiencing adverse conditions. |
| format | Article |
| id | doaj-art-e41fe3b487f3490789d34f95f0e2587c |
| institution | DOAJ |
| issn | 2190-5991 2190-6009 |
| language | English |
| publishDate | 2025-02-01 |
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| series | Journal of Cachexia, Sarcopenia and Muscle |
| spelling | doaj-art-e41fe3b487f3490789d34f95f0e2587c2025-08-20T02:53:13ZengWileyJournal of Cachexia, Sarcopenia and Muscle2190-59912190-60092025-02-01161n/an/a10.1002/jcsm.13676Cut‐Off Points for Low Relative 30‐s Sit‐to‐Stand Power and Their Associations With Adverse Health ConditionsMikel Garcia‐Aguirre0Ivan Baltasar‐Fernandez1Julian Alcazar2Jose Losa‐Reyna3Ana Alfaro‐Acha4Ignacio Ara5Leocadio Rodriguez‐Mañas6Luis M. Alegre7Francisco J. Garcia‐Garcia8GENUD Toledo Research Group, Faculty of Sport Sciences University of Castilla‐La Mancha Toledo SpainGENUD Toledo Research Group, Faculty of Sport Sciences University of Castilla‐La Mancha Toledo SpainGENUD Toledo Research Group, Faculty of Sport Sciences University of Castilla‐La Mancha Toledo SpainCentro de Investigación Biomédica en Red Fragilidad y Envejecimiento Saludable (CIBERFES) Instituto de Salud Carlos III Madrid SpainCentro de Investigación Biomédica en Red Fragilidad y Envejecimiento Saludable (CIBERFES) Instituto de Salud Carlos III Madrid SpainGENUD Toledo Research Group, Faculty of Sport Sciences University of Castilla‐La Mancha Toledo SpainCentro de Investigación Biomédica en Red Fragilidad y Envejecimiento Saludable (CIBERFES) Instituto de Salud Carlos III Madrid SpainGENUD Toledo Research Group, Faculty of Sport Sciences University of Castilla‐La Mancha Toledo SpainCentro de Investigación Biomédica en Red Fragilidad y Envejecimiento Saludable (CIBERFES) Instituto de Salud Carlos III Madrid SpainABSTRACT Background Despite muscle power derived from the 5‐rep sit‐to‐stand (STS) test having been demonstrated to be a valuable biomarker in older individuals, there is limited information regarding muscle power derived from the 30‐s STS test, a widely used test in the clinical setting. This study aimed (i) to compare relative 30‐s STS power values between older men and women, (ii) to identify cut‐off points for low relative 30‐s STS power, (iii) to compare the prevalence of low relative STS power between sexes and (iv) to evaluate the association of low relative 30‐s STS power with adverse conditions in older people. Methods A total of 1475 community‐dwelling older adults (65–98 years; 45% men) from the Toledo Study for Healthy Aging were included. Relative STS power was assessed using the 30‐s STS test and the Alcazar's equation. Adverse health conditions considered encompassed frailty, depression, disability in basic (BADL) and instrumental activities of daily living (IADL), cognitive impairment and low habitual gait speed (HGS). Results Relative STS power decreased linearly at an average rate of 1.0% year−1 in men and 1.5% year−1 in women. The cut‐off points for low relative STS power were 2.53 and 2.01 W·kg−1 for men and women, respectively. The prevalence of low relative STS power was significantly lower in older men compared with older women (43.5% vs. 50.0%, respectively; p = 0.005). In men, low relative STS power was associated with frailty (OR [95% CI] = 4.4 [2.4–8.0]), cognitive impairment (OR [95% CI] = 1.7 [1.0–2.7]), disability in BADL (OR [95% CI] = 4.5 [1.5–13.8]) and low HGS (OR [95% CI] = 3.4 [1.9–5.9]). In women, low relative STS power was associated with frailty (OR [95% CI] = 5.2 [3.5–7.7]), disability in BADL (OR [95% CI] = 4.3 [1.8–9.9]) and IADL (OR [95% CI] = 3.1 [2.2–4.3]) and low HGS (OR [95% CI] = 6.1 [2.8–13.1]). No associations were found between low relative STS power and disability in IADL or depression in men, nor between low relative STS power and cognitive impairment or depression in women. Conclusion Relative STS power decreased with increasing age in both men and women. The provided sex‐specific cut‐off points for low relative STS power using the 30‐s STS test adequately identified older people with frailty and were associated with an increased risk of experiencing adverse conditions.https://doi.org/10.1002/jcsm.13676ageingdisabilityfrailtyfunctional declinehealthy ageingmuscle power |
| spellingShingle | Mikel Garcia‐Aguirre Ivan Baltasar‐Fernandez Julian Alcazar Jose Losa‐Reyna Ana Alfaro‐Acha Ignacio Ara Leocadio Rodriguez‐Mañas Luis M. Alegre Francisco J. Garcia‐Garcia Cut‐Off Points for Low Relative 30‐s Sit‐to‐Stand Power and Their Associations With Adverse Health Conditions Journal of Cachexia, Sarcopenia and Muscle ageing disability frailty functional decline healthy ageing muscle power |
| title | Cut‐Off Points for Low Relative 30‐s Sit‐to‐Stand Power and Their Associations With Adverse Health Conditions |
| title_full | Cut‐Off Points for Low Relative 30‐s Sit‐to‐Stand Power and Their Associations With Adverse Health Conditions |
| title_fullStr | Cut‐Off Points for Low Relative 30‐s Sit‐to‐Stand Power and Their Associations With Adverse Health Conditions |
| title_full_unstemmed | Cut‐Off Points for Low Relative 30‐s Sit‐to‐Stand Power and Their Associations With Adverse Health Conditions |
| title_short | Cut‐Off Points for Low Relative 30‐s Sit‐to‐Stand Power and Their Associations With Adverse Health Conditions |
| title_sort | cut off points for low relative 30 s sit to stand power and their associations with adverse health conditions |
| topic | ageing disability frailty functional decline healthy ageing muscle power |
| url | https://doi.org/10.1002/jcsm.13676 |
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