Predicting the Gender-based Aerobic Capacity in Chronic Obstructive Pulmonary Disease Patients with superadded Infection: A Study Protocol
Introduction: Chronic Obstructive Pulmonary Disease (COPD), a prevalent respiratory condition, can be prevented and treated. Among various triggers, infections are a leading cause of COPD exacerbations. Assessing aerobic capacity is essential in the management of COPD, as it serves as a fundamental...
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JCDR Research and Publications Private Limited
2025-06-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://jcdr.net/articles/PDF/21076/75022_CE[Ra1]_F(SL)_QC(PS_SS)_PF1(RI_SS)_PFA(IS)_PN(IS).pdf |
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| author | Prachi Rana Subhasish Chatterjee Sameer Singhal |
| author_facet | Prachi Rana Subhasish Chatterjee Sameer Singhal |
| author_sort | Prachi Rana |
| collection | DOAJ |
| description | Introduction: Chronic Obstructive Pulmonary Disease (COPD), a prevalent respiratory condition, can be prevented and treated. Among various triggers, infections are a leading cause of COPD exacerbations. Assessing aerobic capacity is essential in the management of COPD, as it serves as a fundamental indicator of both quality of life and mortality. However, determining this target value necessitates the estimation of a gender-based predictive aerobic capacity value for each individual.
Need of the study: The newly developed gender-based reference equation for aerobic capacity may have the potential to accurately calculate predicted values that assess the individual patient’s aerobic capacity.
Aim: To develop a gender-based prediction equation to assess aerobic capacity in COPD patients with infection.
Materials and Methods: This cross-sectional study will recruit COPD patients with infections from the In-Patient Department (IPD) at a tertiary care super-specialty hospital (Maharishi Markandeshwar Institute of Medical Sciences and Research, Ambala, Haryana, India), using purposive sampling be conducted over a period of one year (from July 2024 to June 2025). The Forced Expiratory Volume in 1 second to Forced Vital Capacity (FEV1/FVC) ratio will be recorded using the post-bronchodilator PFT report, while aerobic capacity will be assessed through the Six-Minute Walk Test (6MWT) for 80 participants. Data will be analysed using IBM Statistical Package for the Social Sciences (SPSS) version 26.0. Depending on the data type, Chi-square, Spearman’s, or Pearson’s tests will be used to assess the relationship between FEV1/FVC and 6MWT. Multivariate linear regression with a step-wise approach will be employed to create a predictive equation for aerobic capacity. Subsequently, a standardised equation for aerobic capacity will be derived. |
| format | Article |
| id | doaj-art-e41e5f5b664b4cb3a5e1a485937fd7b3 |
| institution | OA Journals |
| issn | 2249-782X 0973-709X |
| language | English |
| publishDate | 2025-06-01 |
| publisher | JCDR Research and Publications Private Limited |
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| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj-art-e41e5f5b664b4cb3a5e1a485937fd7b32025-08-20T02:31:02ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2025-06-01196YK01YK0410.7860/JCDR/2025/75022.21076Predicting the Gender-based Aerobic Capacity in Chronic Obstructive Pulmonary Disease Patients with superadded Infection: A Study ProtocolPrachi Rana0Subhasish Chatterjee1Sameer Singhal2PhD Research Scholar, Department of Physiotherapy, Maharishi Markandeshwar (Deemed to be University), Mullana, Ambala, Haryana, India.Associate Professor, Maharishi Markandeshwar Institute of Pharmaceutical Research (MMIPR), Maharishi Markandeshwar (Deemed to be University), Mullana, Ambala, Haryana, India.Professor, Maharishi Markandeshwar Institute of Medical Sciences and Research, Maharishi Markandeshwar (Deemed to be University), Mullana, Ambala, Haryana, India.Introduction: Chronic Obstructive Pulmonary Disease (COPD), a prevalent respiratory condition, can be prevented and treated. Among various triggers, infections are a leading cause of COPD exacerbations. Assessing aerobic capacity is essential in the management of COPD, as it serves as a fundamental indicator of both quality of life and mortality. However, determining this target value necessitates the estimation of a gender-based predictive aerobic capacity value for each individual. Need of the study: The newly developed gender-based reference equation for aerobic capacity may have the potential to accurately calculate predicted values that assess the individual patient’s aerobic capacity. Aim: To develop a gender-based prediction equation to assess aerobic capacity in COPD patients with infection. Materials and Methods: This cross-sectional study will recruit COPD patients with infections from the In-Patient Department (IPD) at a tertiary care super-specialty hospital (Maharishi Markandeshwar Institute of Medical Sciences and Research, Ambala, Haryana, India), using purposive sampling be conducted over a period of one year (from July 2024 to June 2025). The Forced Expiratory Volume in 1 second to Forced Vital Capacity (FEV1/FVC) ratio will be recorded using the post-bronchodilator PFT report, while aerobic capacity will be assessed through the Six-Minute Walk Test (6MWT) for 80 participants. Data will be analysed using IBM Statistical Package for the Social Sciences (SPSS) version 26.0. Depending on the data type, Chi-square, Spearman’s, or Pearson’s tests will be used to assess the relationship between FEV1/FVC and 6MWT. Multivariate linear regression with a step-wise approach will be employed to create a predictive equation for aerobic capacity. Subsequently, a standardised equation for aerobic capacity will be derived.https://jcdr.net/articles/PDF/21076/75022_CE[Ra1]_F(SL)_QC(PS_SS)_PF1(RI_SS)_PFA(IS)_PN(IS).pdfforced expiratory volumerespiratory function testssix-minute walk test |
| spellingShingle | Prachi Rana Subhasish Chatterjee Sameer Singhal Predicting the Gender-based Aerobic Capacity in Chronic Obstructive Pulmonary Disease Patients with superadded Infection: A Study Protocol Journal of Clinical and Diagnostic Research forced expiratory volume respiratory function tests six-minute walk test |
| title | Predicting the Gender-based Aerobic Capacity in Chronic Obstructive Pulmonary Disease Patients with superadded Infection: A Study Protocol |
| title_full | Predicting the Gender-based Aerobic Capacity in Chronic Obstructive Pulmonary Disease Patients with superadded Infection: A Study Protocol |
| title_fullStr | Predicting the Gender-based Aerobic Capacity in Chronic Obstructive Pulmonary Disease Patients with superadded Infection: A Study Protocol |
| title_full_unstemmed | Predicting the Gender-based Aerobic Capacity in Chronic Obstructive Pulmonary Disease Patients with superadded Infection: A Study Protocol |
| title_short | Predicting the Gender-based Aerobic Capacity in Chronic Obstructive Pulmonary Disease Patients with superadded Infection: A Study Protocol |
| title_sort | predicting the gender based aerobic capacity in chronic obstructive pulmonary disease patients with superadded infection a study protocol |
| topic | forced expiratory volume respiratory function tests six-minute walk test |
| url | https://jcdr.net/articles/PDF/21076/75022_CE[Ra1]_F(SL)_QC(PS_SS)_PF1(RI_SS)_PFA(IS)_PN(IS).pdf |
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