CD8<sup>+</sup>CD28<sup>+</sup>PD1<sup>−</sup> T Cells as a Prognostic Biomarker in Endometrial Cancer

CD8<sup>+</sup>CD28<sup>+</sup>PD1<sup>−</sup> T Cells as a Prognostic Biomarker in Endometrial Cancer

Endometrial cancer (EC) is an immunogenic tumor, with CD8<sup>+</sup> T cells playing a pivotal role in antitumor immunity. Overexpression of PD1 suppresses T cell function by inhibiting CD28, a critical co-stimulatory molecule. Classifying CD8<sup>+</sup> T cells based on PD...

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Bibliographic Details
Main Authors: Yufei Nie, Lin Yang, Yanan Zhang, Hongyan Guo
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Current Oncology
Subjects:
endometrial cancer
PD1
CD28
immune microenvironment
prognosis
Online Access:https://www.mdpi.com/1718-7729/32/3/121
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