Antimicrobial resistance levels amongst staphylococci isolated from clinical cases of bovine mastitis in Kosovo

Introduction: Mastitis is one of the most frequent and costly disease in cattle. We studied milk samples from cattle with mastitis from farms in Kosovo to identify mastitis-causing pathogens and possible effective antibiotics. Our ultimate goal is to help implement adequate antibiotic management and...

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Main Authors: Ibrahim Mehmeti, Behlul Behluli, Mergim Mestani, Arsim Ademi, Ingolf F Nes, Dzung B Diep
Format: Article
Language:English
Published: The Journal of Infection in Developing Countries 2016-10-01
Series:Journal of Infection in Developing Countries
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Online Access:https://jidc.org/index.php/journal/article/view/7912
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author Ibrahim Mehmeti
Behlul Behluli
Mergim Mestani
Arsim Ademi
Ingolf F Nes
Dzung B Diep
author_facet Ibrahim Mehmeti
Behlul Behluli
Mergim Mestani
Arsim Ademi
Ingolf F Nes
Dzung B Diep
author_sort Ibrahim Mehmeti
collection DOAJ
description Introduction: Mastitis is one of the most frequent and costly disease in cattle. We studied milk samples from cattle with mastitis from farms in Kosovo to identify mastitis-causing pathogens and possible effective antibiotics. Our ultimate goal is to help implement adequate antibiotic management and treatment practices in Kosovo Methodology: A total of 152 milk samples were collected from cows with clinical mastitis from different farms in Kosovo. After identification of microorganisms, antibiotic susceptibility and the occurrence of enterotoxins was investigated. Results: Staphylococci were found in 89 samples, of which 58 were coagulase negative and 31 coagulase positive. S. aureus was isolated from 27 samples, S. epidermidis from 25, and S. chromogenes from 15, while other species of staphylococci were isolated from the remaining 22 isolates. Interestingly, the bacterial diversity was different between cows in different periods of lactation and among different breeds. Most of the isolates (76/89) were resistant to two or more antibiotics. The highest resistance was to penicillin and ampicillin (> 65%), followed by tetracycline, oxacillin, streptomycin, chloramphenicol (> 23%), and less than 3% to erythromycin. Of the 89 isolates, 40 produced enterotoxins that were most frequently typed as A and C. Conclusions: We detected human bacterial pathogens in the cultures of milk samples from cows with mastitis. The isolates demonstrated resistance to two or more antibiotics, some of which are frequently used to treat animal and human infections. We recommend increased control and more stringent use of antibiotics in veterinary as well as human medicine.
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spelling doaj-art-e40c641e0617471eac766b3def0e653c2025-08-20T02:57:13ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802016-10-01101010.3855/jidc.7912Antimicrobial resistance levels amongst staphylococci isolated from clinical cases of bovine mastitis in KosovoIbrahim Mehmeti0Behlul Behluli1Mergim Mestani2Arsim Ademi3Ingolf F Nes4Dzung B Diep5Norwegian University of Life Sciences, Ås, NorwayFaculty of Agriculture and Veterinary, University of Prishtina Hasan Prishtina, Prishtina, KosovoFaculty of Agriculture and Veterinary, University of Prishtina Hasan Prishtina, Prishtina, KosovoNorwegian University of Life Sciences, Ås, NorwayNorwegian University of Life Sciences, Ås, NorwayNorwegian University of Life Sciences, Ås, NorwayIntroduction: Mastitis is one of the most frequent and costly disease in cattle. We studied milk samples from cattle with mastitis from farms in Kosovo to identify mastitis-causing pathogens and possible effective antibiotics. Our ultimate goal is to help implement adequate antibiotic management and treatment practices in Kosovo Methodology: A total of 152 milk samples were collected from cows with clinical mastitis from different farms in Kosovo. After identification of microorganisms, antibiotic susceptibility and the occurrence of enterotoxins was investigated. Results: Staphylococci were found in 89 samples, of which 58 were coagulase negative and 31 coagulase positive. S. aureus was isolated from 27 samples, S. epidermidis from 25, and S. chromogenes from 15, while other species of staphylococci were isolated from the remaining 22 isolates. Interestingly, the bacterial diversity was different between cows in different periods of lactation and among different breeds. Most of the isolates (76/89) were resistant to two or more antibiotics. The highest resistance was to penicillin and ampicillin (> 65%), followed by tetracycline, oxacillin, streptomycin, chloramphenicol (> 23%), and less than 3% to erythromycin. Of the 89 isolates, 40 produced enterotoxins that were most frequently typed as A and C. Conclusions: We detected human bacterial pathogens in the cultures of milk samples from cows with mastitis. The isolates demonstrated resistance to two or more antibiotics, some of which are frequently used to treat animal and human infections. We recommend increased control and more stringent use of antibiotics in veterinary as well as human medicine. https://jidc.org/index.php/journal/article/view/7912bovine mastitisstaphylococcimolecular identificationantibiotic resistanceenterotoxins
spellingShingle Ibrahim Mehmeti
Behlul Behluli
Mergim Mestani
Arsim Ademi
Ingolf F Nes
Dzung B Diep
Antimicrobial resistance levels amongst staphylococci isolated from clinical cases of bovine mastitis in Kosovo
Journal of Infection in Developing Countries
bovine mastitis
staphylococci
molecular identification
antibiotic resistance
enterotoxins
title Antimicrobial resistance levels amongst staphylococci isolated from clinical cases of bovine mastitis in Kosovo
title_full Antimicrobial resistance levels amongst staphylococci isolated from clinical cases of bovine mastitis in Kosovo
title_fullStr Antimicrobial resistance levels amongst staphylococci isolated from clinical cases of bovine mastitis in Kosovo
title_full_unstemmed Antimicrobial resistance levels amongst staphylococci isolated from clinical cases of bovine mastitis in Kosovo
title_short Antimicrobial resistance levels amongst staphylococci isolated from clinical cases of bovine mastitis in Kosovo
title_sort antimicrobial resistance levels amongst staphylococci isolated from clinical cases of bovine mastitis in kosovo
topic bovine mastitis
staphylococci
molecular identification
antibiotic resistance
enterotoxins
url https://jidc.org/index.php/journal/article/view/7912
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