Instant-Ylid: ein lagerfähiges und gebrauchsfertiges Wittig-Reagenz
Mixtures prepared from alkyltriphenylphosphonium bromides and powdered sodium amide can be stored indefinitely. Upon addition of an ethereal solvent, however, they immediately generate the ylide which then may be reacted with aldehydes, ketones or formiates. The use of such “instant-ylid” mixtures...
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| Format: | Article |
| Language: | deu |
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Swiss Chemical Society
1982-10-01
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| Series: | CHIMIA |
| Online Access: | https://www.chimia.ch/chimia/article/view/9569 |
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| _version_ | 1850170599585873920 |
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| author | Manfred Schlosser Bruno Schaub |
| author_facet | Manfred Schlosser Bruno Schaub |
| author_sort | Manfred Schlosser |
| collection | DOAJ |
| description |
Mixtures prepared from alkyltriphenylphosphonium bromides and powdered sodium amide can be stored indefinitely. Upon addition of an ethereal solvent, however, they immediately generate the ylide which then may be reacted with aldehydes, ketones or formiates. The use of such “instant-ylid” mixtures offers distinct advantages over conventional Wittig procedures: optimum yields (even with enolisable ketones), highest cis/trans-ratios, largest range of applicability, shortest reaction times and easiest handling.
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| format | Article |
| id | doaj-art-e409f8ddcc964fb3afdd96d4694839a4 |
| institution | OA Journals |
| issn | 0009-4293 2673-2424 |
| language | deu |
| publishDate | 1982-10-01 |
| publisher | Swiss Chemical Society |
| record_format | Article |
| series | CHIMIA |
| spelling | doaj-art-e409f8ddcc964fb3afdd96d4694839a42025-08-20T02:20:26ZdeuSwiss Chemical SocietyCHIMIA0009-42932673-24241982-10-01361010.2533/chimia.1982.396Instant-Ylid: ein lagerfähiges und gebrauchsfertiges Wittig-ReagenzManfred Schlosser0Bruno Schaub1Institut de Chimie organique de l’Université, Rue de la Barre 2, CH-1005 LausanneInstitut de Chimie organique de l’Université, Rue de la Barre 2, CH-1005 Lausanne Mixtures prepared from alkyltriphenylphosphonium bromides and powdered sodium amide can be stored indefinitely. Upon addition of an ethereal solvent, however, they immediately generate the ylide which then may be reacted with aldehydes, ketones or formiates. The use of such “instant-ylid” mixtures offers distinct advantages over conventional Wittig procedures: optimum yields (even with enolisable ketones), highest cis/trans-ratios, largest range of applicability, shortest reaction times and easiest handling. https://www.chimia.ch/chimia/article/view/9569 |
| spellingShingle | Manfred Schlosser Bruno Schaub Instant-Ylid: ein lagerfähiges und gebrauchsfertiges Wittig-Reagenz CHIMIA |
| title | Instant-Ylid: ein lagerfähiges und gebrauchsfertiges Wittig-Reagenz |
| title_full | Instant-Ylid: ein lagerfähiges und gebrauchsfertiges Wittig-Reagenz |
| title_fullStr | Instant-Ylid: ein lagerfähiges und gebrauchsfertiges Wittig-Reagenz |
| title_full_unstemmed | Instant-Ylid: ein lagerfähiges und gebrauchsfertiges Wittig-Reagenz |
| title_short | Instant-Ylid: ein lagerfähiges und gebrauchsfertiges Wittig-Reagenz |
| title_sort | instant ylid ein lagerfahiges und gebrauchsfertiges wittig reagenz |
| url | https://www.chimia.ch/chimia/article/view/9569 |
| work_keys_str_mv | AT manfredschlosser instantylideinlagerfahigesundgebrauchsfertigeswittigreagenz AT brunoschaub instantylideinlagerfahigesundgebrauchsfertigeswittigreagenz |