Global burden of enteric infections related foodborne diseases, 1990–2021: findings from the Global Burden of Disease Study 2021
Background: Understanding the global burden of enteric infections is crucial for prioritizing control strategies for foodborne and waterborne diseases. This study aimed to assess the global burden of enteric infections in 2021 and identify risk factors from One Health aspects. Methods: Leveraging th...
Saved in:
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-01-01
|
| Series: | Science in One Health |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2949704324000143 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850060861217964032 |
|---|---|
| author | Tianyun Li Ne Qiang Yujia Bao Yongxuan Li Shi Zhao Ka Chun Chong Xiaobei Deng Xiaoxi Zhang Jinjun Ran Lefei Han |
| author_facet | Tianyun Li Ne Qiang Yujia Bao Yongxuan Li Shi Zhao Ka Chun Chong Xiaobei Deng Xiaoxi Zhang Jinjun Ran Lefei Han |
| author_sort | Tianyun Li |
| collection | DOAJ |
| description | Background: Understanding the global burden of enteric infections is crucial for prioritizing control strategies for foodborne and waterborne diseases. This study aimed to assess the global burden of enteric infections in 2021 and identify risk factors from One Health aspects. Methods: Leveraging the Global Burden of Disease (GBD) 2021 database, the incidence, disability-adjusted life years (DALYs), and deaths of enteric infections and the subtypes were estimated, including diarrheal diseases, typhoid and paratyphoid fever, invasive non-typhoidal Salmonella (iNTS) infections, and other intestinal infectious diseases. The estimates were quantified by absolute number, age-standardized incidence rate (ASIR), age-standardized mortality rate (ASMR) and age-standardized DALY rate with 95% uncertainty intervals (UIs). Thirteen pathogens and three risk factors associated with diarrheal diseases were analyzed. Results: In 2021, the global age-standardized DALY rate of enteric infections was 1020.15 per 100,000 popultion (95% UI: 822.70–1259.39 per 100,000 population) with an estimated annual percentage change (EAPC) of −4.11% (95% confidence interval: −4.31% to −3.90%) in 1990–2021. A larger burden was observed in regions with lower socio-demographic index (SDI) levels. Diarrheal disease was the most serious subtype with Western Sub-Saharan Africa exhibiting the highest age-standardized DALY rate (2769.81 per 100,000 population, 95% UI: 1976.80–3674.41 per 100,000 population). Children under 5 and adults over 65 years suffered more from diarrheal diseases with the former experiencing the highest global age-standardized DALY rate (9382.46 per 100,000 population, 95% UI: 6771.76–13,075.12 per 100,000 population). Rotavirus remained the leading cause of diarrheal diseases despite a cross-year decline in the observed age-standardized DALY rate. Unsafe water, sanitation, and handwashing contributed most to the disease burden. Conclusion: The reduced burden of enteric infections suggested the effectiveness of previous control strategies; however, more efforts should be made in vulnerable regions and populations through a One Health approach. |
| format | Article |
| id | doaj-art-e408cf3582334853b06e6ca50f28a7cc |
| institution | DOAJ |
| issn | 2949-7043 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Science in One Health |
| spelling | doaj-art-e408cf3582334853b06e6ca50f28a7cc2025-08-20T02:50:26ZengElsevierScience in One Health2949-70432024-01-01310007510.1016/j.soh.2024.100075Global burden of enteric infections related foodborne diseases, 1990–2021: findings from the Global Burden of Disease Study 2021Tianyun Li0Ne Qiang1Yujia Bao2Yongxuan Li3Shi Zhao4Ka Chun Chong5Xiaobei Deng6Xiaoxi Zhang7Jinjun Ran8Lefei Han9School of Global Health, Chinese Center for Tropical Diseases Research, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China; One Health Center, Shanghai Jiao Tong University-The University of Edinburgh, Shanghai 200025, China; School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, ChinaSchool of Global Health, Chinese Center for Tropical Diseases Research, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China; One Health Center, Shanghai Jiao Tong University-The University of Edinburgh, Shanghai 200025, China; School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, ChinaSchool of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, ChinaSchool of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, ChinaSchool of Public Health, Tianjin Medical University, Tianjin 300070, ChinaCentre for Health Systems and Policy Research, Jockey Club School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong, ChinaSchool of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, ChinaSchool of Global Health, Chinese Center for Tropical Diseases Research, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China; One Health Center, Shanghai Jiao Tong University-The University of Edinburgh, Shanghai 200025, ChinaSchool of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China; Corresponding author.School of Global Health, Chinese Center for Tropical Diseases Research, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China; One Health Center, Shanghai Jiao Tong University-The University of Edinburgh, Shanghai 200025, China; Corresponding author. School of Global Health, Chinese Center for Tropical Diseases Research, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.Background: Understanding the global burden of enteric infections is crucial for prioritizing control strategies for foodborne and waterborne diseases. This study aimed to assess the global burden of enteric infections in 2021 and identify risk factors from One Health aspects. Methods: Leveraging the Global Burden of Disease (GBD) 2021 database, the incidence, disability-adjusted life years (DALYs), and deaths of enteric infections and the subtypes were estimated, including diarrheal diseases, typhoid and paratyphoid fever, invasive non-typhoidal Salmonella (iNTS) infections, and other intestinal infectious diseases. The estimates were quantified by absolute number, age-standardized incidence rate (ASIR), age-standardized mortality rate (ASMR) and age-standardized DALY rate with 95% uncertainty intervals (UIs). Thirteen pathogens and three risk factors associated with diarrheal diseases were analyzed. Results: In 2021, the global age-standardized DALY rate of enteric infections was 1020.15 per 100,000 popultion (95% UI: 822.70–1259.39 per 100,000 population) with an estimated annual percentage change (EAPC) of −4.11% (95% confidence interval: −4.31% to −3.90%) in 1990–2021. A larger burden was observed in regions with lower socio-demographic index (SDI) levels. Diarrheal disease was the most serious subtype with Western Sub-Saharan Africa exhibiting the highest age-standardized DALY rate (2769.81 per 100,000 population, 95% UI: 1976.80–3674.41 per 100,000 population). Children under 5 and adults over 65 years suffered more from diarrheal diseases with the former experiencing the highest global age-standardized DALY rate (9382.46 per 100,000 population, 95% UI: 6771.76–13,075.12 per 100,000 population). Rotavirus remained the leading cause of diarrheal diseases despite a cross-year decline in the observed age-standardized DALY rate. Unsafe water, sanitation, and handwashing contributed most to the disease burden. Conclusion: The reduced burden of enteric infections suggested the effectiveness of previous control strategies; however, more efforts should be made in vulnerable regions and populations through a One Health approach.http://www.sciencedirect.com/science/article/pii/S2949704324000143Enteric infectionsDiarrheal diseaseFoodborneDisease burdenGlobal healthOne Health |
| spellingShingle | Tianyun Li Ne Qiang Yujia Bao Yongxuan Li Shi Zhao Ka Chun Chong Xiaobei Deng Xiaoxi Zhang Jinjun Ran Lefei Han Global burden of enteric infections related foodborne diseases, 1990–2021: findings from the Global Burden of Disease Study 2021 Science in One Health Enteric infections Diarrheal disease Foodborne Disease burden Global health One Health |
| title | Global burden of enteric infections related foodborne diseases, 1990–2021: findings from the Global Burden of Disease Study 2021 |
| title_full | Global burden of enteric infections related foodborne diseases, 1990–2021: findings from the Global Burden of Disease Study 2021 |
| title_fullStr | Global burden of enteric infections related foodborne diseases, 1990–2021: findings from the Global Burden of Disease Study 2021 |
| title_full_unstemmed | Global burden of enteric infections related foodborne diseases, 1990–2021: findings from the Global Burden of Disease Study 2021 |
| title_short | Global burden of enteric infections related foodborne diseases, 1990–2021: findings from the Global Burden of Disease Study 2021 |
| title_sort | global burden of enteric infections related foodborne diseases 1990 2021 findings from the global burden of disease study 2021 |
| topic | Enteric infections Diarrheal disease Foodborne Disease burden Global health One Health |
| url | http://www.sciencedirect.com/science/article/pii/S2949704324000143 |
| work_keys_str_mv | AT tianyunli globalburdenofentericinfectionsrelatedfoodbornediseases19902021findingsfromtheglobalburdenofdiseasestudy2021 AT neqiang globalburdenofentericinfectionsrelatedfoodbornediseases19902021findingsfromtheglobalburdenofdiseasestudy2021 AT yujiabao globalburdenofentericinfectionsrelatedfoodbornediseases19902021findingsfromtheglobalburdenofdiseasestudy2021 AT yongxuanli globalburdenofentericinfectionsrelatedfoodbornediseases19902021findingsfromtheglobalburdenofdiseasestudy2021 AT shizhao globalburdenofentericinfectionsrelatedfoodbornediseases19902021findingsfromtheglobalburdenofdiseasestudy2021 AT kachunchong globalburdenofentericinfectionsrelatedfoodbornediseases19902021findingsfromtheglobalburdenofdiseasestudy2021 AT xiaobeideng globalburdenofentericinfectionsrelatedfoodbornediseases19902021findingsfromtheglobalburdenofdiseasestudy2021 AT xiaoxizhang globalburdenofentericinfectionsrelatedfoodbornediseases19902021findingsfromtheglobalburdenofdiseasestudy2021 AT jinjunran globalburdenofentericinfectionsrelatedfoodbornediseases19902021findingsfromtheglobalburdenofdiseasestudy2021 AT lefeihan globalburdenofentericinfectionsrelatedfoodbornediseases19902021findingsfromtheglobalburdenofdiseasestudy2021 |