All biomass bovine serum albumin/alginate hydrogels: robust mechanical strength and excellent shape memory performance regardless of protein denaturation
Shape memory materials made from biomacromolecules are eco-friendly but often display low mechanical strength and inferior shape memory performance. This study innovatively created a shape memory hydrogel (SMH) using bovine serum albumin (BSA) and alginate. Through a protein-unfolding-che...
Saved in:
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Academia.edu Journals
2025-04-01
|
| Series: | Academia Materials Science |
| Online Access: | https://www.academia.edu/128576972/All_biomass_bovine_serum_albumin_alginate_hydrogels_robust_mechanical_strength_and_excellent_shape_memory_performance_regardless_of_protein_denaturation |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850104754986811392 |
|---|---|
| author | Shaorong Zong Xiaohui Chu Jia Kang Cungang Gao Pengxin Jia Yue Sun Rui Nian Wenfa Yu Kaiming Wang |
| author_facet | Shaorong Zong Xiaohui Chu Jia Kang Cungang Gao Pengxin Jia Yue Sun Rui Nian Wenfa Yu Kaiming Wang |
| author_sort | Shaorong Zong |
| collection | DOAJ |
| description |
Shape memory materials made from biomacromolecules are eco-friendly but often display low mechanical strength and inferior shape memory performance. This study innovatively created a shape memory hydrogel (SMH) using bovine serum albumin (BSA) and alginate. Through a protein-unfolding-chemical coupling strategy, the prepared hydrogel achieved outstanding mechanical strength that made it mechanically robust enough to be handled in practical applications. The hydrogel showed excellent shape memory performance, with a shape fixing ratio of 93.8% and a shape recovery ratio of 100%. The complexation between alginate and Fe3+ made the shape memory performance insensitive to the secondary structure of BSA, remaining consistent even after extreme denaturation treatment. Composed entirely of biomacromolecules, the SMH was fully biodegradable and sustainable. In summary, the BSA/alginate-based SMH, with high mechanical strength, excellent shape memory performance, and biodegradability, holds great potential as sustainable and versatile shape memory hydrogels. |
| format | Article |
| id | doaj-art-e4084ef54d2040c6a38b1d4510829475 |
| institution | DOAJ |
| issn | 2997-2027 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Academia.edu Journals |
| record_format | Article |
| series | Academia Materials Science |
| spelling | doaj-art-e4084ef54d2040c6a38b1d45108294752025-08-20T02:39:15ZengAcademia.edu JournalsAcademia Materials Science2997-20272025-04-012210.20935/AcadMatSci7614All biomass bovine serum albumin/alginate hydrogels: robust mechanical strength and excellent shape memory performance regardless of protein denaturationShaorong Zong0Xiaohui Chu1Jia Kang2Cungang Gao3Pengxin Jia4Yue Sun5Rui Nian6Wenfa Yu7Kaiming Wang8School of Biological Science and Technology, University of Jinan, No. 336, Nanxinzhuang West Road, Jinan 250024, China.Qingdao Municipal Hospital, No. 1 Jiaozhou Road, Qingdao 266011, China.CAS Key Laboratory of Biobased Materials, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, No. 189, Songling Road, Qingdao 266101, China.CAS Key Laboratory of Biobased Materials, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, No. 189, Songling Road, Qingdao 266101, China.CAS Key Laboratory of Biobased Materials, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, No. 189, Songling Road, Qingdao 266101, China.CAS Key Laboratory of Biobased Materials, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, No. 189, Songling Road, Qingdao 266101, China.CAS Key Laboratory of Biobased Materials, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, No. 189, Songling Road, Qingdao 266101, China.CAS Key Laboratory of Biobased Materials, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, No. 189, Songling Road, Qingdao 266101, China.School of Biological Science and Technology, University of Jinan, No. 336, Nanxinzhuang West Road, Jinan 250024, China. Shape memory materials made from biomacromolecules are eco-friendly but often display low mechanical strength and inferior shape memory performance. This study innovatively created a shape memory hydrogel (SMH) using bovine serum albumin (BSA) and alginate. Through a protein-unfolding-chemical coupling strategy, the prepared hydrogel achieved outstanding mechanical strength that made it mechanically robust enough to be handled in practical applications. The hydrogel showed excellent shape memory performance, with a shape fixing ratio of 93.8% and a shape recovery ratio of 100%. The complexation between alginate and Fe3+ made the shape memory performance insensitive to the secondary structure of BSA, remaining consistent even after extreme denaturation treatment. Composed entirely of biomacromolecules, the SMH was fully biodegradable and sustainable. In summary, the BSA/alginate-based SMH, with high mechanical strength, excellent shape memory performance, and biodegradability, holds great potential as sustainable and versatile shape memory hydrogels.https://www.academia.edu/128576972/All_biomass_bovine_serum_albumin_alginate_hydrogels_robust_mechanical_strength_and_excellent_shape_memory_performance_regardless_of_protein_denaturation |
| spellingShingle | Shaorong Zong Xiaohui Chu Jia Kang Cungang Gao Pengxin Jia Yue Sun Rui Nian Wenfa Yu Kaiming Wang All biomass bovine serum albumin/alginate hydrogels: robust mechanical strength and excellent shape memory performance regardless of protein denaturation Academia Materials Science |
| title | All biomass bovine serum albumin/alginate hydrogels: robust mechanical strength and excellent shape memory performance regardless of protein denaturation |
| title_full | All biomass bovine serum albumin/alginate hydrogels: robust mechanical strength and excellent shape memory performance regardless of protein denaturation |
| title_fullStr | All biomass bovine serum albumin/alginate hydrogels: robust mechanical strength and excellent shape memory performance regardless of protein denaturation |
| title_full_unstemmed | All biomass bovine serum albumin/alginate hydrogels: robust mechanical strength and excellent shape memory performance regardless of protein denaturation |
| title_short | All biomass bovine serum albumin/alginate hydrogels: robust mechanical strength and excellent shape memory performance regardless of protein denaturation |
| title_sort | all biomass bovine serum albumin alginate hydrogels robust mechanical strength and excellent shape memory performance regardless of protein denaturation |
| url | https://www.academia.edu/128576972/All_biomass_bovine_serum_albumin_alginate_hydrogels_robust_mechanical_strength_and_excellent_shape_memory_performance_regardless_of_protein_denaturation |
| work_keys_str_mv | AT shaorongzong allbiomassbovineserumalbuminalginatehydrogelsrobustmechanicalstrengthandexcellentshapememoryperformanceregardlessofproteindenaturation AT xiaohuichu allbiomassbovineserumalbuminalginatehydrogelsrobustmechanicalstrengthandexcellentshapememoryperformanceregardlessofproteindenaturation AT jiakang allbiomassbovineserumalbuminalginatehydrogelsrobustmechanicalstrengthandexcellentshapememoryperformanceregardlessofproteindenaturation AT cunganggao allbiomassbovineserumalbuminalginatehydrogelsrobustmechanicalstrengthandexcellentshapememoryperformanceregardlessofproteindenaturation AT pengxinjia allbiomassbovineserumalbuminalginatehydrogelsrobustmechanicalstrengthandexcellentshapememoryperformanceregardlessofproteindenaturation AT yuesun allbiomassbovineserumalbuminalginatehydrogelsrobustmechanicalstrengthandexcellentshapememoryperformanceregardlessofproteindenaturation AT ruinian allbiomassbovineserumalbuminalginatehydrogelsrobustmechanicalstrengthandexcellentshapememoryperformanceregardlessofproteindenaturation AT wenfayu allbiomassbovineserumalbuminalginatehydrogelsrobustmechanicalstrengthandexcellentshapememoryperformanceregardlessofproteindenaturation AT kaimingwang allbiomassbovineserumalbuminalginatehydrogelsrobustmechanicalstrengthandexcellentshapememoryperformanceregardlessofproteindenaturation |