From MDT to MTB: the paradigm revolution in pediatric cancer treatment in the era of precision medicine
Abstract Pediatric cancer treatment is undergoing a paradigm shift from multidisciplinary team (MDT) approaches to molecular tumor boards (MTB). This article analyzes the limitations of traditional MDT, the technological reconstruction path of MTB, and the dual challenges of ethics and resource allo...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Springer
2025-07-01
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| Series: | Holistic Integrative Oncology |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s44178-025-00178-0 |
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| _version_ | 1849767327950700544 |
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| author | Haiyan Cheng Larry L. Wang |
| author_facet | Haiyan Cheng Larry L. Wang |
| author_sort | Haiyan Cheng |
| collection | DOAJ |
| description | Abstract Pediatric cancer treatment is undergoing a paradigm shift from multidisciplinary team (MDT) approaches to molecular tumor boards (MTB). This article analyzes the limitations of traditional MDT, the technological reconstruction path of MTB, and the dual challenges of ethics and resource allocation in precision medicine. It reveals the fundamental transformation of the diagnostic and treatment system driven by genomics and proposes integrated strategies for future development. |
| format | Article |
| id | doaj-art-e405a1b5dff046f29c1d04d72f9d4cd6 |
| institution | DOAJ |
| issn | 2731-4529 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Springer |
| record_format | Article |
| series | Holistic Integrative Oncology |
| spelling | doaj-art-e405a1b5dff046f29c1d04d72f9d4cd62025-08-20T03:04:15ZengSpringerHolistic Integrative Oncology2731-45292025-07-01411510.1007/s44178-025-00178-0From MDT to MTB: the paradigm revolution in pediatric cancer treatment in the era of precision medicineHaiyan Cheng0Larry L. Wang1Department of Surgical Oncology, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s HealthDepartment of Pathology and Laboratory Medicine, Children’s Hospital Los AngelesAbstract Pediatric cancer treatment is undergoing a paradigm shift from multidisciplinary team (MDT) approaches to molecular tumor boards (MTB). This article analyzes the limitations of traditional MDT, the technological reconstruction path of MTB, and the dual challenges of ethics and resource allocation in precision medicine. It reveals the fundamental transformation of the diagnostic and treatment system driven by genomics and proposes integrated strategies for future development.https://doi.org/10.1007/s44178-025-00178-0Pediatric cancerPrecision medicineMDTMTB |
| spellingShingle | Haiyan Cheng Larry L. Wang From MDT to MTB: the paradigm revolution in pediatric cancer treatment in the era of precision medicine Holistic Integrative Oncology Pediatric cancer Precision medicine MDT MTB |
| title | From MDT to MTB: the paradigm revolution in pediatric cancer treatment in the era of precision medicine |
| title_full | From MDT to MTB: the paradigm revolution in pediatric cancer treatment in the era of precision medicine |
| title_fullStr | From MDT to MTB: the paradigm revolution in pediatric cancer treatment in the era of precision medicine |
| title_full_unstemmed | From MDT to MTB: the paradigm revolution in pediatric cancer treatment in the era of precision medicine |
| title_short | From MDT to MTB: the paradigm revolution in pediatric cancer treatment in the era of precision medicine |
| title_sort | from mdt to mtb the paradigm revolution in pediatric cancer treatment in the era of precision medicine |
| topic | Pediatric cancer Precision medicine MDT MTB |
| url | https://doi.org/10.1007/s44178-025-00178-0 |
| work_keys_str_mv | AT haiyancheng frommdttomtbtheparadigmrevolutioninpediatriccancertreatmentintheeraofprecisionmedicine AT larrylwang frommdttomtbtheparadigmrevolutioninpediatriccancertreatmentintheeraofprecisionmedicine |