Nontyphoidal Salmonella Gastroenteritis in a Tertiary Children’s Hospital in Southern China: Characteristics and Dietary Considerations
Background. Nontyphoidal Salmonella infection is a common cause for acute bacterial gastroenteritis in children in China. There have been no reports of the prevalence of lactose intolerance or food allergies in children with nontyphoidal Salmonella infection. The aim of this study was to characteriz...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2018-01-01
|
| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2018/3097468 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832560420493197312 |
|---|---|
| author | Lu Ren Min Yang Lanlan Geng Peiyu Chen Huan Chen Sitang Gong Ding-You Li |
| author_facet | Lu Ren Min Yang Lanlan Geng Peiyu Chen Huan Chen Sitang Gong Ding-You Li |
| author_sort | Lu Ren |
| collection | DOAJ |
| description | Background. Nontyphoidal Salmonella infection is a common cause for acute bacterial gastroenteritis in children in China. There have been no reports of the prevalence of lactose intolerance or food allergies in children with nontyphoidal Salmonella infection. The aim of this study was to characterize nontyphoidal Salmonella gastroenteritis in a tertiary children’s hospital and evaluate clinical presentation, lactose intolerance, and food allergies in children with prolonged nontyphoidal Salmonella gastroenteritis. Methods. A retrospective case-series analysis was carried out in a tertiary children’s hospital in Guangzhou, China. We included all infants and children who were diagnosed with nontyphoidal Salmonella gastroenteritis between 1 January 2014 and 31 December 2016. Patients’ clinical features, feeding patterns, laboratory tests, and treatment outcomes were reviewed. Results. A total of 142 infants and children were diagnosed with nontyphoidal Salmonella gastroenteritis. 52.1% of cases occurred in infants ≤ 12 months of age and the majority (89.4%) in children younger than 3 years old. The most common symptoms were diarrhea (100%), fever (62%), and vomiting (18.3%). Salmonella Typhimurium was the predominant serotype, accounting for 82.4%. 91.5% of patients were treated with antibiotics. Forty-one (28.9%) and 9 (6.3%) children improved with a lactose-free diet and hypoallergenic formula, respectively, when diarrhea persisted for more than a week. Conclusions. Salmonella Typhimurium was the predominant serotype. Most patients with nontyphoidal Salmonella gastroenteritis were younger than 3 years old. Lactose intolerance occurred frequently in children with nontyphoidal Salmonella gastroenteritis and dietary modification should be considered when diarrhea is persistent and prolonged. |
| format | Article |
| id | doaj-art-e3f7ae23233749478870440bb1b99b3c |
| institution | Kabale University |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-e3f7ae23233749478870440bb1b99b3c2025-02-03T01:27:39ZengWileyGastroenterology Research and Practice1687-61211687-630X2018-01-01201810.1155/2018/30974683097468Nontyphoidal Salmonella Gastroenteritis in a Tertiary Children’s Hospital in Southern China: Characteristics and Dietary ConsiderationsLu Ren0Min Yang1Lanlan Geng2Peiyu Chen3Huan Chen4Sitang Gong5Ding-You Li6Department of Gastroenterology, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou 510623, ChinaDepartment of Gastroenterology, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou 510623, ChinaDepartment of Gastroenterology, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou 510623, ChinaDepartment of Gastroenterology, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou 510623, ChinaDepartment of Gastroenterology, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou 510623, ChinaDepartment of Gastroenterology, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou 510623, ChinaDivision of Gastroenterology, Children’s Mercy Kansas City, University of Missouri-Kansas City School of Medicine, Kansas City, MO 64108, USABackground. Nontyphoidal Salmonella infection is a common cause for acute bacterial gastroenteritis in children in China. There have been no reports of the prevalence of lactose intolerance or food allergies in children with nontyphoidal Salmonella infection. The aim of this study was to characterize nontyphoidal Salmonella gastroenteritis in a tertiary children’s hospital and evaluate clinical presentation, lactose intolerance, and food allergies in children with prolonged nontyphoidal Salmonella gastroenteritis. Methods. A retrospective case-series analysis was carried out in a tertiary children’s hospital in Guangzhou, China. We included all infants and children who were diagnosed with nontyphoidal Salmonella gastroenteritis between 1 January 2014 and 31 December 2016. Patients’ clinical features, feeding patterns, laboratory tests, and treatment outcomes were reviewed. Results. A total of 142 infants and children were diagnosed with nontyphoidal Salmonella gastroenteritis. 52.1% of cases occurred in infants ≤ 12 months of age and the majority (89.4%) in children younger than 3 years old. The most common symptoms were diarrhea (100%), fever (62%), and vomiting (18.3%). Salmonella Typhimurium was the predominant serotype, accounting for 82.4%. 91.5% of patients were treated with antibiotics. Forty-one (28.9%) and 9 (6.3%) children improved with a lactose-free diet and hypoallergenic formula, respectively, when diarrhea persisted for more than a week. Conclusions. Salmonella Typhimurium was the predominant serotype. Most patients with nontyphoidal Salmonella gastroenteritis were younger than 3 years old. Lactose intolerance occurred frequently in children with nontyphoidal Salmonella gastroenteritis and dietary modification should be considered when diarrhea is persistent and prolonged.http://dx.doi.org/10.1155/2018/3097468 |
| spellingShingle | Lu Ren Min Yang Lanlan Geng Peiyu Chen Huan Chen Sitang Gong Ding-You Li Nontyphoidal Salmonella Gastroenteritis in a Tertiary Children’s Hospital in Southern China: Characteristics and Dietary Considerations Gastroenterology Research and Practice |
| title | Nontyphoidal Salmonella Gastroenteritis in a Tertiary Children’s Hospital in Southern China: Characteristics and Dietary Considerations |
| title_full | Nontyphoidal Salmonella Gastroenteritis in a Tertiary Children’s Hospital in Southern China: Characteristics and Dietary Considerations |
| title_fullStr | Nontyphoidal Salmonella Gastroenteritis in a Tertiary Children’s Hospital in Southern China: Characteristics and Dietary Considerations |
| title_full_unstemmed | Nontyphoidal Salmonella Gastroenteritis in a Tertiary Children’s Hospital in Southern China: Characteristics and Dietary Considerations |
| title_short | Nontyphoidal Salmonella Gastroenteritis in a Tertiary Children’s Hospital in Southern China: Characteristics and Dietary Considerations |
| title_sort | nontyphoidal salmonella gastroenteritis in a tertiary children s hospital in southern china characteristics and dietary considerations |
| url | http://dx.doi.org/10.1155/2018/3097468 |
| work_keys_str_mv | AT luren nontyphoidalsalmonellagastroenteritisinatertiarychildrenshospitalinsouthernchinacharacteristicsanddietaryconsiderations AT minyang nontyphoidalsalmonellagastroenteritisinatertiarychildrenshospitalinsouthernchinacharacteristicsanddietaryconsiderations AT lanlangeng nontyphoidalsalmonellagastroenteritisinatertiarychildrenshospitalinsouthernchinacharacteristicsanddietaryconsiderations AT peiyuchen nontyphoidalsalmonellagastroenteritisinatertiarychildrenshospitalinsouthernchinacharacteristicsanddietaryconsiderations AT huanchen nontyphoidalsalmonellagastroenteritisinatertiarychildrenshospitalinsouthernchinacharacteristicsanddietaryconsiderations AT sitanggong nontyphoidalsalmonellagastroenteritisinatertiarychildrenshospitalinsouthernchinacharacteristicsanddietaryconsiderations AT dingyouli nontyphoidalsalmonellagastroenteritisinatertiarychildrenshospitalinsouthernchinacharacteristicsanddietaryconsiderations |