New drug formulations of colony-stimulating factors in oncohematology

The use of colony-stimulating factors became an autonomous approach in complex supportive care of blood tumors. By indications of granulocyte colony-stimulating factor (G-CSF) it is possible to reduce of neutropenic period, perform an optimal timing of therapy, decrease a number of infection complic...

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Main Authors: T. T. Valiev, R. R. Fatkhullin, Yu. E. Ryabukhina, P. A. Zeynalova
Format: Article
Language:Russian
Published: ABV-press 2023-03-01
Series:Онкогематология
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Online Access:https://oncohematology.abvpress.ru/ongm/article/view/805
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author T. T. Valiev
R. R. Fatkhullin
Yu. E. Ryabukhina
P. A. Zeynalova
author_facet T. T. Valiev
R. R. Fatkhullin
Yu. E. Ryabukhina
P. A. Zeynalova
author_sort T. T. Valiev
collection DOAJ
description The use of colony-stimulating factors became an autonomous approach in complex supportive care of blood tumors. By indications of granulocyte colony-stimulating factor (G-CSF) it is possible to reduce of neutropenic period, perform an optimal timing of therapy, decrease a number of infection complications. The development and active use of a new G-CSF drug formulation – pegfilgrastim do not decrease the duration of neutropenic period significantly, but reduced the frequency of drug administration, period of hospitalization and a probability of “ineffective” hematopoietic stem cell mobilization.In the current issue it is presented the results of modern studies, which demonstrate advantages of PEG-G-CSF in contrast to G-CSF, algorithm for febrile neutropenia risk assessment, the questions for G-CSF administrations in patients with blood tumors.
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institution Kabale University
issn 1818-8346
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language Russian
publishDate 2023-03-01
publisher ABV-press
record_format Article
series Онкогематология
spelling doaj-art-e3f3c1ddbf4f4887af275b2e59f8b9082025-08-20T03:35:33ZrusABV-pressОнкогематология1818-83462413-40232023-03-0118112613110.17650/1818-8346-2023-18-1-126-131677New drug formulations of colony-stimulating factors in oncohematologyT. T. Valiev0R. R. Fatkhullin1Yu. E. Ryabukhina2P. A. Zeynalova3N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia; I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of RussiaClinical Hospital “Lapino” of the “Mother and Child” Group of companiesI.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University); Clinical Hospital “Lapino” of the “Mother and Child” Group of companiesThe use of colony-stimulating factors became an autonomous approach in complex supportive care of blood tumors. By indications of granulocyte colony-stimulating factor (G-CSF) it is possible to reduce of neutropenic period, perform an optimal timing of therapy, decrease a number of infection complications. The development and active use of a new G-CSF drug formulation – pegfilgrastim do not decrease the duration of neutropenic period significantly, but reduced the frequency of drug administration, period of hospitalization and a probability of “ineffective” hematopoietic stem cell mobilization.In the current issue it is presented the results of modern studies, which demonstrate advantages of PEG-G-CSF in contrast to G-CSF, algorithm for febrile neutropenia risk assessment, the questions for G-CSF administrations in patients with blood tumors.https://oncohematology.abvpress.ru/ongm/article/view/805leukemialymphomasupportive carecolony-stimulating factorpegfilgrastim
spellingShingle T. T. Valiev
R. R. Fatkhullin
Yu. E. Ryabukhina
P. A. Zeynalova
New drug formulations of colony-stimulating factors in oncohematology
Онкогематология
leukemia
lymphoma
supportive care
colony-stimulating factor
pegfilgrastim
title New drug formulations of colony-stimulating factors in oncohematology
title_full New drug formulations of colony-stimulating factors in oncohematology
title_fullStr New drug formulations of colony-stimulating factors in oncohematology
title_full_unstemmed New drug formulations of colony-stimulating factors in oncohematology
title_short New drug formulations of colony-stimulating factors in oncohematology
title_sort new drug formulations of colony stimulating factors in oncohematology
topic leukemia
lymphoma
supportive care
colony-stimulating factor
pegfilgrastim
url https://oncohematology.abvpress.ru/ongm/article/view/805
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AT rrfatkhullin newdrugformulationsofcolonystimulatingfactorsinoncohematology
AT yueryabukhina newdrugformulationsofcolonystimulatingfactorsinoncohematology
AT pazeynalova newdrugformulationsofcolonystimulatingfactorsinoncohematology