Clinical Trials Evaluating Drug Therapy: Types, Reliability of Results, Place in Modern Evidence-Based Medicine
The article discusses the main methods of evidence in modern medicine. Special attention is paid to randomized controlled trials and observational studies. The advantages of randomized controlled trials over observational studies are considered. A comparison of the informative value of randomized co...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Столичная издательская компания
2021-05-01
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| Series: | Рациональная фармакотерапия в кардиологии |
| Subjects: | |
| Online Access: | https://www.rpcardio.online/jour/article/view/2433 |
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| author | S. Yu. Martsevich N. P. Kutishenko Yu. V. Lukina M. M. Lukyanov O. M. Drapkina |
| author_facet | S. Yu. Martsevich N. P. Kutishenko Yu. V. Lukina M. M. Lukyanov O. M. Drapkina |
| author_sort | S. Yu. Martsevich |
| collection | DOAJ |
| description | The article discusses the main methods of evidence in modern medicine. Special attention is paid to randomized controlled trials and observational studies. The advantages of randomized controlled trials over observational studies are considered. A comparison of the informative value of randomized controlled trials and observational studies in assessing the effect of therapeutic interventions is made. Attention is drawn to situations when conducting randomized controlled trials is not possible and when they become the main source of information. It is emphasized that in order to verify the results of randomized controlled trials in real clinical practice, it is necessary to conduct observational studies. The basic principles of conducting observational studies are considered. |
| format | Article |
| id | doaj-art-e3ed162fc8fe493fb2ba1fe8240b622a |
| institution | Kabale University |
| issn | 1819-6446 2225-3653 |
| language | English |
| publishDate | 2021-05-01 |
| publisher | Столичная издательская компания |
| record_format | Article |
| series | Рациональная фармакотерапия в кардиологии |
| spelling | doaj-art-e3ed162fc8fe493fb2ba1fe8240b622a2025-08-23T10:00:33ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532021-05-0117224925510.20996/1819-6446-2021-04-071873Clinical Trials Evaluating Drug Therapy: Types, Reliability of Results, Place in Modern Evidence-Based MedicineS. Yu. Martsevich0N. P. Kutishenko1Yu. V. Lukina2M. M. Lukyanov3O. M. Drapkina4National Medical Research Center for Therapy and Preventive MedicineNational Medical Research Center for Therapy and Preventive MedicineNational Medical Research Center for Therapy and Preventive MedicineNational Medical Research Center for Therapy and Preventive MedicineNational Medical Research Center for Therapy and Preventive MedicineThe article discusses the main methods of evidence in modern medicine. Special attention is paid to randomized controlled trials and observational studies. The advantages of randomized controlled trials over observational studies are considered. A comparison of the informative value of randomized controlled trials and observational studies in assessing the effect of therapeutic interventions is made. Attention is drawn to situations when conducting randomized controlled trials is not possible and when they become the main source of information. It is emphasized that in order to verify the results of randomized controlled trials in real clinical practice, it is necessary to conduct observational studies. The basic principles of conducting observational studies are considered.https://www.rpcardio.online/jour/article/view/2433randomized controlled trialsobservational studiescomparison of information contentprinciples of conducting observational studies |
| spellingShingle | S. Yu. Martsevich N. P. Kutishenko Yu. V. Lukina M. M. Lukyanov O. M. Drapkina Clinical Trials Evaluating Drug Therapy: Types, Reliability of Results, Place in Modern Evidence-Based Medicine Рациональная фармакотерапия в кардиологии randomized controlled trials observational studies comparison of information content principles of conducting observational studies |
| title | Clinical Trials Evaluating Drug Therapy: Types, Reliability of Results, Place in Modern Evidence-Based Medicine |
| title_full | Clinical Trials Evaluating Drug Therapy: Types, Reliability of Results, Place in Modern Evidence-Based Medicine |
| title_fullStr | Clinical Trials Evaluating Drug Therapy: Types, Reliability of Results, Place in Modern Evidence-Based Medicine |
| title_full_unstemmed | Clinical Trials Evaluating Drug Therapy: Types, Reliability of Results, Place in Modern Evidence-Based Medicine |
| title_short | Clinical Trials Evaluating Drug Therapy: Types, Reliability of Results, Place in Modern Evidence-Based Medicine |
| title_sort | clinical trials evaluating drug therapy types reliability of results place in modern evidence based medicine |
| topic | randomized controlled trials observational studies comparison of information content principles of conducting observational studies |
| url | https://www.rpcardio.online/jour/article/view/2433 |
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