Synthesis and Evaluation of Novel Bis-Chalcone Derivatives Containing a Thiophene Moiety as Potential Anticancer Agents: In Vitro, In Silico , and Mechanistic Studies
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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American Chemical Society
2025-06-01
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| Series: | ACS Omega |
| Online Access: | https://doi.org/10.1021/acsomega.5c02394 |
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| author | Esraa M. Fathi Mostafa E. Salem Farid M. Sroor Fatma G Mohamed Ahmed H. M. Elwahy Mohamed Abdel-Megid Ismail A. Abdelhamid Marwan Emara |
| author_facet | Esraa M. Fathi Mostafa E. Salem Farid M. Sroor Fatma G Mohamed Ahmed H. M. Elwahy Mohamed Abdel-Megid Ismail A. Abdelhamid Marwan Emara |
| author_sort | Esraa M. Fathi |
| collection | DOAJ |
| format | Article |
| id | doaj-art-e3e9ff503751416bb617b665280d5be7 |
| institution | Kabale University |
| issn | 2470-1343 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | American Chemical Society |
| record_format | Article |
| series | ACS Omega |
| spelling | doaj-art-e3e9ff503751416bb617b665280d5be72025-08-20T03:29:26ZengAmerican Chemical SocietyACS Omega2470-13432025-06-011024259212593710.1021/acsomega.5c02394Synthesis and Evaluation of Novel Bis-Chalcone Derivatives Containing a Thiophene Moiety as Potential Anticancer Agents: In Vitro, In Silico , and Mechanistic StudiesEsraa M. Fathi0Mostafa E. Salem1Farid M. Sroor2Fatma G Mohamed3Ahmed H. M. Elwahy4Mohamed Abdel-Megid5Ismail A. Abdelhamid6Marwan Emara7Department of Chemistry (Biochemistry Branch), Faculty of Science, Cairo University, Giza, EgyptChemistry Department, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi ArabiaOrganometallic and Organometalloid Chemistry Department, National Research Centre, Giza, Cairo, EgyptDepartment of Chemistry (Biochemistry Branch), Faculty of Science, Cairo University, Giza, EgyptDepartment of Chemistry, Faculty of Science, Cairo University, Giza, EgyptChemistry Department, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi ArabiaDepartment of Chemistry, Faculty of Science, Cairo University, Giza, EgyptCenter for Aging and Associated Diseases, Zewail City of Science, Technology and Innovation, Giza, Egypthttps://doi.org/10.1021/acsomega.5c02394 |
| spellingShingle | Esraa M. Fathi Mostafa E. Salem Farid M. Sroor Fatma G Mohamed Ahmed H. M. Elwahy Mohamed Abdel-Megid Ismail A. Abdelhamid Marwan Emara Synthesis and Evaluation of Novel Bis-Chalcone Derivatives Containing a Thiophene Moiety as Potential Anticancer Agents: In Vitro, In Silico , and Mechanistic Studies ACS Omega |
| title | Synthesis and Evaluation of Novel Bis-Chalcone Derivatives Containing a Thiophene Moiety as Potential Anticancer Agents: In Vitro, In Silico , and Mechanistic Studies |
| title_full | Synthesis and Evaluation of Novel Bis-Chalcone Derivatives Containing a Thiophene Moiety as Potential Anticancer Agents: In Vitro, In Silico , and Mechanistic Studies |
| title_fullStr | Synthesis and Evaluation of Novel Bis-Chalcone Derivatives Containing a Thiophene Moiety as Potential Anticancer Agents: In Vitro, In Silico , and Mechanistic Studies |
| title_full_unstemmed | Synthesis and Evaluation of Novel Bis-Chalcone Derivatives Containing a Thiophene Moiety as Potential Anticancer Agents: In Vitro, In Silico , and Mechanistic Studies |
| title_short | Synthesis and Evaluation of Novel Bis-Chalcone Derivatives Containing a Thiophene Moiety as Potential Anticancer Agents: In Vitro, In Silico , and Mechanistic Studies |
| title_sort | synthesis and evaluation of novel bis chalcone derivatives containing a thiophene moiety as potential anticancer agents in vitro in silico and mechanistic studies |
| url | https://doi.org/10.1021/acsomega.5c02394 |
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