DIAGNOSTIC CRITERIA FOR THE FORMATION OF GLAUCOMATOUS OPTIC NEUROPATHY AT THE VARIOUS STAGES OF THE DISEASE
Purpose: to identify the most informative diagnostic criteria for the formation of glaucomatous optic neuropathy at various stages of the pathological process. Methods: 94 people with early stages of glaucoma were examined using spectral optical tomography, chromatic methods of perimetry, electroret...
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Scientific Сentre for Family Health and Human Reproduction Problems
2016-11-01
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| Series: | Acta Biomedica Scientifica |
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| Online Access: | https://www.actabiomedica.ru/jour/article/view/337 |
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| author | A. G. Shchuko Y. S. Pyatova T. N. Iureva A. S. Grishchuk |
| author_facet | A. G. Shchuko Y. S. Pyatova T. N. Iureva A. S. Grishchuk |
| author_sort | A. G. Shchuko |
| collection | DOAJ |
| description | Purpose: to identify the most informative diagnostic criteria for the formation of glaucomatous optic neuropathy at various stages of the pathological process. Methods: 94 people with early stages of glaucoma were examined using spectral optical tomography, chromatic methods of perimetry, electroretinography and electrophysiological examination. The following main criteria for inclusion of patients in the study were identified: elevated levels of intraocular pressure (IOP), visual acuity not less than 0.6, similar in dimensions to the value of the optic nerve, which allowed comparing the results of research in these patients populations. Thus, through careful clinical analysis of data and assessment of excavation size of the optic nerve, using certain optical coherence tomography (OCT), all patients were divided into 3 groups. To get an accurate representation of the formation features of glaucomatous neuropathy it was necessary to evaluate not only the structural changes of the retina and optic nerve, but also the changes of their functional activity in all groups. Results: The most important criterion for the structural changes of the retina in patients in the latent stage of the pathological process was the global indicator of the volume loss of ganglionic complex (GLV %). IOP decrease in this group of patients was accompanied by normalization criteria of central perimetry, PERG, which is indicating their functional transient depression on the background of elevated intraocular pressure. Decrease perimeter indices of all kinds of computer perimetry were observed in patients with more advanced stage of disease. |
| format | Article |
| id | doaj-art-e3e9f9d61f494c72afb75273bff768a6 |
| institution | Kabale University |
| issn | 2541-9420 2587-9596 |
| language | Russian |
| publishDate | 2016-11-01 |
| publisher | Scientific Сentre for Family Health and Human Reproduction Problems |
| record_format | Article |
| series | Acta Biomedica Scientifica |
| spelling | doaj-art-e3e9f9d61f494c72afb75273bff768a62025-08-20T03:56:54ZrusScientific Сentre for Family Health and Human Reproduction ProblemsActa Biomedica Scientifica2541-94202587-95962016-11-011614314710.12737/23796337DIAGNOSTIC CRITERIA FOR THE FORMATION OF GLAUCOMATOUS OPTIC NEUROPATHY AT THE VARIOUS STAGES OF THE DISEASEA. G. Shchuko0Y. S. Pyatova1T. N. Iureva2A. S. Grishchuk3Иркутский филиал ФГАУ «МНТК «Микрохирургия глаза» им. акад. С.Н. Федорова» МЗ РФ; ГБОУ ДПО «Иркутская государственная медицинская академия последипломного образования» Минздрава РоссииИркутский филиал ФГАУ «МНТК «Микрохирургия глаза» им. акад. С.Н. Федорова» МЗ РФИркутский филиал ФГАУ «МНТК «Микрохирургия глаза» им. акад. С.Н. Федорова» МЗ РФ; ФГБОУ ВО «Иркутский государственный медицинский университет» Минздрава РоссииИркутский филиал ФГАУ «МНТК «Микрохирургия глаза» им. акад. С.Н. Федорова» МЗ РФ; ГБОУ ДПО «Иркутская государственная медицинская академия последипломного образования» Минздрава РоссииPurpose: to identify the most informative diagnostic criteria for the formation of glaucomatous optic neuropathy at various stages of the pathological process. Methods: 94 people with early stages of glaucoma were examined using spectral optical tomography, chromatic methods of perimetry, electroretinography and electrophysiological examination. The following main criteria for inclusion of patients in the study were identified: elevated levels of intraocular pressure (IOP), visual acuity not less than 0.6, similar in dimensions to the value of the optic nerve, which allowed comparing the results of research in these patients populations. Thus, through careful clinical analysis of data and assessment of excavation size of the optic nerve, using certain optical coherence tomography (OCT), all patients were divided into 3 groups. To get an accurate representation of the formation features of glaucomatous neuropathy it was necessary to evaluate not only the structural changes of the retina and optic nerve, but also the changes of their functional activity in all groups. Results: The most important criterion for the structural changes of the retina in patients in the latent stage of the pathological process was the global indicator of the volume loss of ganglionic complex (GLV %). IOP decrease in this group of patients was accompanied by normalization criteria of central perimetry, PERG, which is indicating their functional transient depression on the background of elevated intraocular pressure. Decrease perimeter indices of all kinds of computer perimetry were observed in patients with more advanced stage of disease.https://www.actabiomedica.ru/jour/article/view/337latent stage of glaucomacomplex of ganglion cellsoct diagnostics of glaucoma |
| spellingShingle | A. G. Shchuko Y. S. Pyatova T. N. Iureva A. S. Grishchuk DIAGNOSTIC CRITERIA FOR THE FORMATION OF GLAUCOMATOUS OPTIC NEUROPATHY AT THE VARIOUS STAGES OF THE DISEASE Acta Biomedica Scientifica latent stage of glaucoma complex of ganglion cells oct diagnostics of glaucoma |
| title | DIAGNOSTIC CRITERIA FOR THE FORMATION OF GLAUCOMATOUS OPTIC NEUROPATHY AT THE VARIOUS STAGES OF THE DISEASE |
| title_full | DIAGNOSTIC CRITERIA FOR THE FORMATION OF GLAUCOMATOUS OPTIC NEUROPATHY AT THE VARIOUS STAGES OF THE DISEASE |
| title_fullStr | DIAGNOSTIC CRITERIA FOR THE FORMATION OF GLAUCOMATOUS OPTIC NEUROPATHY AT THE VARIOUS STAGES OF THE DISEASE |
| title_full_unstemmed | DIAGNOSTIC CRITERIA FOR THE FORMATION OF GLAUCOMATOUS OPTIC NEUROPATHY AT THE VARIOUS STAGES OF THE DISEASE |
| title_short | DIAGNOSTIC CRITERIA FOR THE FORMATION OF GLAUCOMATOUS OPTIC NEUROPATHY AT THE VARIOUS STAGES OF THE DISEASE |
| title_sort | diagnostic criteria for the formation of glaucomatous optic neuropathy at the various stages of the disease |
| topic | latent stage of glaucoma complex of ganglion cells oct diagnostics of glaucoma |
| url | https://www.actabiomedica.ru/jour/article/view/337 |
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