Zero contrast technique in doubly committed subarterial ventricular septal defect closure in patient with body weight less than 10 kg: a case report

IntroductionThe complex anatomy of DCSA VSD, its proximity to valvular and conduction tissues, and concerns about radiation and contrast make transcatheter closure particularly challenging in pediatric patients. While zero-fluoroscopy closure was not achievable in this case, we successfully performe...

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Main Authors: Radityo Prakoso, Rina Ariani, Aditya Agita Sembiring, Brian Mendel, Oktavia Lilyasari
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Cardiovascular Medicine
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Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2025.1564232/full
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author Radityo Prakoso
Rina Ariani
Aditya Agita Sembiring
Brian Mendel
Oktavia Lilyasari
author_facet Radityo Prakoso
Rina Ariani
Aditya Agita Sembiring
Brian Mendel
Oktavia Lilyasari
author_sort Radityo Prakoso
collection DOAJ
description IntroductionThe complex anatomy of DCSA VSD, its proximity to valvular and conduction tissues, and concerns about radiation and contrast make transcatheter closure particularly challenging in pediatric patients. While zero-fluoroscopy closure was not achievable in this case, we successfully performed zero-contrast transcatheter closure in a baby weighing less than 10 kg. This report highlights the feasibility and early outcomes of this approach at our institution.Case illustrationAn 18-month-old, 9 kg boy with a history of feeding difficulties, failure to thrive, and breathlessness since 14 days of age underwent transcatheter closure of a doubly committed subarterial (DCSA) ventricular septal defect (VSD). Transthoracic echocardiography revealed a 4–5 mm left-to-right shunting VSD with preserved ventricular function. Initial attempts to cross the VSD under zero-fluoroscopy guidance using various catheters were unsuccessful, necessitating fluoroscopic assistance without contrast. A Konar-MF VSD occluder (7/5 mm) was successfully deployed retrogradely, achieving complete defect closure with no residual shunt or valve dysfunction. Post-procedure, the patient remained asymptomatic, with excellent device positioning and no complications noted at follow-up.ConclusionThis case demonstrates the feasibility of zero-contrast percutaneous DCSA-VSD closure in selected patients weighing less than 10 kg. Further studies are needed to validate its safety and long-term outcomes.
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spelling doaj-art-e3e72b922f2047ccb8b612482e0050622025-08-20T02:37:33ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2025-07-011210.3389/fcvm.2025.15642321564232Zero contrast technique in doubly committed subarterial ventricular septal defect closure in patient with body weight less than 10 kg: a case reportRadityo Prakoso0Rina Ariani1Aditya Agita Sembiring2Brian Mendel3Oktavia Lilyasari4Division of Pediatric Cardiology and Congenital Heart Disease, Department of Cardiology and Vascular Medicine, National Cardiovascular Centre of Harapan Kita, Universitas Indonesia, Jakarta, IndonesiaDivision of Non-invasive Diagnostic and Cardiovascular Imaging, Department of Cardiology and Vascular Medicine, National Cardiovascular Centre of Harapan Kita, Universitas Indonesia, Jakarta, IndonesiaDivision of Pediatric Cardiology and Congenital Heart Disease, Department of Cardiology and Vascular Medicine, National Cardiovascular Centre of Harapan Kita, Universitas Indonesia, Jakarta, IndonesiaDepartment of Cardiology and Vascular Medicine, National Cardiovascular Centre of Harapan Kita, Universitas Indonesia, Jakarta, IndonesiaDivision of Pediatric Cardiology and Congenital Heart Disease, Department of Cardiology and Vascular Medicine, National Cardiovascular Centre of Harapan Kita, Universitas Indonesia, Jakarta, IndonesiaIntroductionThe complex anatomy of DCSA VSD, its proximity to valvular and conduction tissues, and concerns about radiation and contrast make transcatheter closure particularly challenging in pediatric patients. While zero-fluoroscopy closure was not achievable in this case, we successfully performed zero-contrast transcatheter closure in a baby weighing less than 10 kg. This report highlights the feasibility and early outcomes of this approach at our institution.Case illustrationAn 18-month-old, 9 kg boy with a history of feeding difficulties, failure to thrive, and breathlessness since 14 days of age underwent transcatheter closure of a doubly committed subarterial (DCSA) ventricular septal defect (VSD). Transthoracic echocardiography revealed a 4–5 mm left-to-right shunting VSD with preserved ventricular function. Initial attempts to cross the VSD under zero-fluoroscopy guidance using various catheters were unsuccessful, necessitating fluoroscopic assistance without contrast. A Konar-MF VSD occluder (7/5 mm) was successfully deployed retrogradely, achieving complete defect closure with no residual shunt or valve dysfunction. Post-procedure, the patient remained asymptomatic, with excellent device positioning and no complications noted at follow-up.ConclusionThis case demonstrates the feasibility of zero-contrast percutaneous DCSA-VSD closure in selected patients weighing less than 10 kg. Further studies are needed to validate its safety and long-term outcomes.https://www.frontiersin.org/articles/10.3389/fcvm.2025.1564232/fullDCSA VSDsmall body weightTTEzero-contrasttransthoracic echocardiogram
spellingShingle Radityo Prakoso
Rina Ariani
Aditya Agita Sembiring
Brian Mendel
Oktavia Lilyasari
Zero contrast technique in doubly committed subarterial ventricular septal defect closure in patient with body weight less than 10 kg: a case report
Frontiers in Cardiovascular Medicine
DCSA VSD
small body weight
TTE
zero-contrast
transthoracic echocardiogram
title Zero contrast technique in doubly committed subarterial ventricular septal defect closure in patient with body weight less than 10 kg: a case report
title_full Zero contrast technique in doubly committed subarterial ventricular septal defect closure in patient with body weight less than 10 kg: a case report
title_fullStr Zero contrast technique in doubly committed subarterial ventricular septal defect closure in patient with body weight less than 10 kg: a case report
title_full_unstemmed Zero contrast technique in doubly committed subarterial ventricular septal defect closure in patient with body weight less than 10 kg: a case report
title_short Zero contrast technique in doubly committed subarterial ventricular septal defect closure in patient with body weight less than 10 kg: a case report
title_sort zero contrast technique in doubly committed subarterial ventricular septal defect closure in patient with body weight less than 10 kg a case report
topic DCSA VSD
small body weight
TTE
zero-contrast
transthoracic echocardiogram
url https://www.frontiersin.org/articles/10.3389/fcvm.2025.1564232/full
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