Systemic Lupus Erythematosus with Initial Manifestation as Enlargement in Cervical, Axillary and Inguinal Lymphnodes: A Case Report

Systemic lupus erythematosus (SLE) is a chronic inflammatory disease that may affect the joints, skin, kidneys, lungs, nervous system, and serous membranes and/or other organs. Lymphadenopathy is characterized by changes in the characteristics and size of the lymph nodes. It results from reticuloen...

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Main Authors: Aryan Mohamadfatih Jalal, Niaz AL-barzinji, Sheelan Faroz Aref
Format: Article
Language:English
Published: Faculty of Medicine, University of Kufa 2022-12-01
Series:مجلة الكوفة الطبية
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Online Access:https://journal.uokufa.edu.iq/index.php/kmj/article/view/9769
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author Aryan Mohamadfatih Jalal
Niaz AL-barzinji
Sheelan Faroz Aref
author_facet Aryan Mohamadfatih Jalal
Niaz AL-barzinji
Sheelan Faroz Aref
author_sort Aryan Mohamadfatih Jalal
collection DOAJ
description Systemic lupus erythematosus (SLE) is a chronic inflammatory disease that may affect the joints, skin, kidneys, lungs, nervous system, and serous membranes and/or other organs. Lymphadenopathy is characterized by changes in the characteristics and size of the lymph nodes. It results from reticuloendothelial proliferation secondary to inflammation, infection, or malignancies. Lymphadenopathy is common in SLE. It has been reported that lymph node enlargement is observed in 25-67% of SLE patients. We reported this thirty-three-year patient with presented with lymph node enlargement in cervical, axillary, and inguinal, joint pain, renal involvement and respiratory involvement diagnosed as Systemic lupus erythematosus according to ACR/EULAR criteria immunological and clinical domain SLICC (systemic lupus international collaborating clinics. In conclusion, lymphadenopathy is a manifestation in SLE. As illustrated by the case presented here, it can precede the diagnosis of SLE by many years; It is possible that the factors that induce lymph node proliferation are also responsible for the development of autoantibodies.
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series مجلة الكوفة الطبية
spelling doaj-art-e3e59df02e0047f1a4a48a0aee8337222025-08-20T02:35:43ZengFaculty of Medicine, University of Kufaمجلة الكوفة الطبية1993-517X2709-44642022-12-0118210.36330/kmj.v18i2.9769Systemic Lupus Erythematosus with Initial Manifestation as Enlargement in Cervical, Axillary and Inguinal Lymphnodes: A Case ReportAryan Mohamadfatih Jalal0Niaz AL-barzinji1Sheelan Faroz Aref2Department of Rheumatology, Rizgary Teaching Hospital, student at Kurdistan Board for Medical Specialties, Erbil -IraqHawler medical university, College of medicine, KurdistanIraqDepartment of Rheumatology, Rizgary Teaching Hospital, student at Kurdistan Board for Medical Specialties, Erbil -Iraq Systemic lupus erythematosus (SLE) is a chronic inflammatory disease that may affect the joints, skin, kidneys, lungs, nervous system, and serous membranes and/or other organs. Lymphadenopathy is characterized by changes in the characteristics and size of the lymph nodes. It results from reticuloendothelial proliferation secondary to inflammation, infection, or malignancies. Lymphadenopathy is common in SLE. It has been reported that lymph node enlargement is observed in 25-67% of SLE patients. We reported this thirty-three-year patient with presented with lymph node enlargement in cervical, axillary, and inguinal, joint pain, renal involvement and respiratory involvement diagnosed as Systemic lupus erythematosus according to ACR/EULAR criteria immunological and clinical domain SLICC (systemic lupus international collaborating clinics. In conclusion, lymphadenopathy is a manifestation in SLE. As illustrated by the case presented here, it can precede the diagnosis of SLE by many years; It is possible that the factors that induce lymph node proliferation are also responsible for the development of autoantibodies. https://journal.uokufa.edu.iq/index.php/kmj/article/view/9769Systemic lupus erythematosusLymphadenopathy
spellingShingle Aryan Mohamadfatih Jalal
Niaz AL-barzinji
Sheelan Faroz Aref
Systemic Lupus Erythematosus with Initial Manifestation as Enlargement in Cervical, Axillary and Inguinal Lymphnodes: A Case Report
مجلة الكوفة الطبية
Systemic lupus erythematosus
Lymphadenopathy
title Systemic Lupus Erythematosus with Initial Manifestation as Enlargement in Cervical, Axillary and Inguinal Lymphnodes: A Case Report
title_full Systemic Lupus Erythematosus with Initial Manifestation as Enlargement in Cervical, Axillary and Inguinal Lymphnodes: A Case Report
title_fullStr Systemic Lupus Erythematosus with Initial Manifestation as Enlargement in Cervical, Axillary and Inguinal Lymphnodes: A Case Report
title_full_unstemmed Systemic Lupus Erythematosus with Initial Manifestation as Enlargement in Cervical, Axillary and Inguinal Lymphnodes: A Case Report
title_short Systemic Lupus Erythematosus with Initial Manifestation as Enlargement in Cervical, Axillary and Inguinal Lymphnodes: A Case Report
title_sort systemic lupus erythematosus with initial manifestation as enlargement in cervical axillary and inguinal lymphnodes a case report
topic Systemic lupus erythematosus
Lymphadenopathy
url https://journal.uokufa.edu.iq/index.php/kmj/article/view/9769
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AT sheelanfarozaref systemiclupuserythematosuswithinitialmanifestationasenlargementincervicalaxillaryandinguinallymphnodesacasereport