Informative Value of the Oxygenation Index in the Diagnosis of Acute Respiratory Distress Syndrome

Objective: to study the informative value of the oxygenation index as a criterion for the diagnosis of acute respiratory distress syndrome (ARDS) of varying genesis. Subjects and methods. Seventy-two patients, including 27 women and 45 men, aged 19 to 65 years admitted to an intensive care unit for...

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Main Authors: A. V. Vlasenko, V. V. Moroz, V. N. Yakovlev, V. G. Alekseyev
Format: Article
Language:English
Published: Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia 2009-10-01
Series:Общая реаниматология
Online Access:https://www.reanimatology.com/rmt/article/view/538
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author A. V. Vlasenko
V. V. Moroz
V. N. Yakovlev
V. G. Alekseyev
author_facet A. V. Vlasenko
V. V. Moroz
V. N. Yakovlev
V. G. Alekseyev
author_sort A. V. Vlasenko
collection DOAJ
description Objective: to study the informative value of the oxygenation index as a criterion for the diagnosis of acute respiratory distress syndrome (ARDS) of varying genesis. Subjects and methods. Seventy-two patients, including 27 women and 45 men, aged 19 to 65 years admitted to an intensive care unit for various diseases, in whom ARDS was diagnosed on the basis of the traditional criteria, were prospectively examined. The authors analyzed the causes of acute respiratory failure, the time course of changes in gas exchange and PaO2/FiO2, X-ray picture, and the time of respiratory support when respiratory and nonrespiratory treatments were performed. Results. After correction of the extrapulmonary causes of impaired gas exchange, optimization of respiratory support parameters, and use of aggressive artificial ventilation methods and nonrespiratory treatments, 45 (62.5%) of the 72 examinees diagnosed as having ARDS showed a considerable gas exchange improvement and a steady increase in the oxygenation index more than 300; thus, these patients stopped meeting the criteria of ARDS. Conclusion. The oxygenation index is a rather vulnerable sign of ARDS, the time course of changes in which depends on many pulmonary and extrapulmonary causes, which necessitates a comprehensive evaluation of the degree of lung injury, the causes and severity of respiratory failure and, evidently, the refinement and expansion of the criteria for establishing this diagnosis. Key words: acute lung injury, acute respiratory distress syndrome, acute respiratory failure, oxygenation index.
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spelling doaj-art-e3e41dccf61945cfa42a3a25c10f91ce2025-08-20T02:55:52ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102009-10-015510.15360/1813-9779-2009-5-54538Informative Value of the Oxygenation Index in the Diagnosis of Acute Respiratory Distress SyndromeA. V. VlasenkoV. V. MorozV. N. YakovlevV. G. AlekseyevObjective: to study the informative value of the oxygenation index as a criterion for the diagnosis of acute respiratory distress syndrome (ARDS) of varying genesis. Subjects and methods. Seventy-two patients, including 27 women and 45 men, aged 19 to 65 years admitted to an intensive care unit for various diseases, in whom ARDS was diagnosed on the basis of the traditional criteria, were prospectively examined. The authors analyzed the causes of acute respiratory failure, the time course of changes in gas exchange and PaO2/FiO2, X-ray picture, and the time of respiratory support when respiratory and nonrespiratory treatments were performed. Results. After correction of the extrapulmonary causes of impaired gas exchange, optimization of respiratory support parameters, and use of aggressive artificial ventilation methods and nonrespiratory treatments, 45 (62.5%) of the 72 examinees diagnosed as having ARDS showed a considerable gas exchange improvement and a steady increase in the oxygenation index more than 300; thus, these patients stopped meeting the criteria of ARDS. Conclusion. The oxygenation index is a rather vulnerable sign of ARDS, the time course of changes in which depends on many pulmonary and extrapulmonary causes, which necessitates a comprehensive evaluation of the degree of lung injury, the causes and severity of respiratory failure and, evidently, the refinement and expansion of the criteria for establishing this diagnosis. Key words: acute lung injury, acute respiratory distress syndrome, acute respiratory failure, oxygenation index.https://www.reanimatology.com/rmt/article/view/538
spellingShingle A. V. Vlasenko
V. V. Moroz
V. N. Yakovlev
V. G. Alekseyev
Informative Value of the Oxygenation Index in the Diagnosis of Acute Respiratory Distress Syndrome
Общая реаниматология
title Informative Value of the Oxygenation Index in the Diagnosis of Acute Respiratory Distress Syndrome
title_full Informative Value of the Oxygenation Index in the Diagnosis of Acute Respiratory Distress Syndrome
title_fullStr Informative Value of the Oxygenation Index in the Diagnosis of Acute Respiratory Distress Syndrome
title_full_unstemmed Informative Value of the Oxygenation Index in the Diagnosis of Acute Respiratory Distress Syndrome
title_short Informative Value of the Oxygenation Index in the Diagnosis of Acute Respiratory Distress Syndrome
title_sort informative value of the oxygenation index in the diagnosis of acute respiratory distress syndrome
url https://www.reanimatology.com/rmt/article/view/538
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AT vnyakovlev informativevalueoftheoxygenationindexinthediagnosisofacuterespiratorydistresssyndrome
AT vgalekseyev informativevalueoftheoxygenationindexinthediagnosisofacuterespiratorydistresssyndrome