Case of early infant congenital bilateral axillary vein thrombosis discovered by superficial venous dilatation; a case report

Abstract Background Upper extremity deep venous thrombosis (UEDVT) is a disease caused by angiectopia and hypercoagulation, which result in the superficial vein to become dilatated by the development of collateral circulation. There have been no reports to date of cases of bilateral axillary vein th...

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Main Authors: Hiroki Ishii, Shinichiro Morichi, Yusuke Watanabe, Kanako Hayashi, Gaku Yamanaka
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Pediatrics
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Online Access:https://doi.org/10.1186/s12887-024-05374-x
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author Hiroki Ishii
Shinichiro Morichi
Yusuke Watanabe
Kanako Hayashi
Gaku Yamanaka
author_facet Hiroki Ishii
Shinichiro Morichi
Yusuke Watanabe
Kanako Hayashi
Gaku Yamanaka
author_sort Hiroki Ishii
collection DOAJ
description Abstract Background Upper extremity deep venous thrombosis (UEDVT) is a disease caused by angiectopia and hypercoagulation, which result in the superficial vein to become dilatated by the development of collateral circulation. There have been no reports to date of cases of bilateral axillary vein thrombosis developing in the early infant period. Moreover, whether anticoagulant administration is indicated varies among patients. Case presentation A 1-month-old boy presented with dilatated superficial veins in the right temporalis, right auricle, whole face, and bilateral upper limbs. Venous dilatation of the right temporalis worsened while crying. He had no notable family history. The patient’s heart had a normal structure, and the foramen ovale was patent on transthoracic echocardiography, and closed at 3-months old. Bilateral axillary vein thrombi were displayed on bilateral brachial vein angiography. Anticoagulants were not administered because the patient’s systemic circulation developed normally, and our analysis did not detect any abnormal coagulation disorders in the patient. However, the patient suddenly developed right hemiplegia at 6-months old, which naturally resolved without the administration of anticoagulants. Conclusion In patients presenting with bilateral UEDVT, the administration of anticoagulants should be considered owing to the possibility of vasculitis and congenital abnormal coagulation disorders.
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series BMC Pediatrics
spelling doaj-art-e3e1d5700eeb498dac2a0577f4dbd8832025-08-20T02:12:59ZengBMCBMC Pediatrics1471-24312025-02-012511510.1186/s12887-024-05374-xCase of early infant congenital bilateral axillary vein thrombosis discovered by superficial venous dilatation; a case reportHiroki Ishii0Shinichiro Morichi1Yusuke Watanabe2Kanako Hayashi3Gaku Yamanaka4Department of Pediatrics and Adolescent Medicine, Tokyo Medical University HospitalDepartment of Pediatrics and Adolescent Medicine, Tokyo Medical University HospitalDepartment of Pediatrics and Adolescent Medicine, Tokyo Medical University HospitalDepartment of Pediatrics and Adolescent Medicine, Tokyo Medical University HospitalDepartment of Pediatrics and Adolescent Medicine, Tokyo Medical University HospitalAbstract Background Upper extremity deep venous thrombosis (UEDVT) is a disease caused by angiectopia and hypercoagulation, which result in the superficial vein to become dilatated by the development of collateral circulation. There have been no reports to date of cases of bilateral axillary vein thrombosis developing in the early infant period. Moreover, whether anticoagulant administration is indicated varies among patients. Case presentation A 1-month-old boy presented with dilatated superficial veins in the right temporalis, right auricle, whole face, and bilateral upper limbs. Venous dilatation of the right temporalis worsened while crying. He had no notable family history. The patient’s heart had a normal structure, and the foramen ovale was patent on transthoracic echocardiography, and closed at 3-months old. Bilateral axillary vein thrombi were displayed on bilateral brachial vein angiography. Anticoagulants were not administered because the patient’s systemic circulation developed normally, and our analysis did not detect any abnormal coagulation disorders in the patient. However, the patient suddenly developed right hemiplegia at 6-months old, which naturally resolved without the administration of anticoagulants. Conclusion In patients presenting with bilateral UEDVT, the administration of anticoagulants should be considered owing to the possibility of vasculitis and congenital abnormal coagulation disorders.https://doi.org/10.1186/s12887-024-05374-xAxillary veinUpper extremity deep venous thrombosisSuperficial venous dilatationVascular ultrasonographyBrachial vein angiographyCongenital abnormal coagulation disorder
spellingShingle Hiroki Ishii
Shinichiro Morichi
Yusuke Watanabe
Kanako Hayashi
Gaku Yamanaka
Case of early infant congenital bilateral axillary vein thrombosis discovered by superficial venous dilatation; a case report
BMC Pediatrics
Axillary vein
Upper extremity deep venous thrombosis
Superficial venous dilatation
Vascular ultrasonography
Brachial vein angiography
Congenital abnormal coagulation disorder
title Case of early infant congenital bilateral axillary vein thrombosis discovered by superficial venous dilatation; a case report
title_full Case of early infant congenital bilateral axillary vein thrombosis discovered by superficial venous dilatation; a case report
title_fullStr Case of early infant congenital bilateral axillary vein thrombosis discovered by superficial venous dilatation; a case report
title_full_unstemmed Case of early infant congenital bilateral axillary vein thrombosis discovered by superficial venous dilatation; a case report
title_short Case of early infant congenital bilateral axillary vein thrombosis discovered by superficial venous dilatation; a case report
title_sort case of early infant congenital bilateral axillary vein thrombosis discovered by superficial venous dilatation a case report
topic Axillary vein
Upper extremity deep venous thrombosis
Superficial venous dilatation
Vascular ultrasonography
Brachial vein angiography
Congenital abnormal coagulation disorder
url https://doi.org/10.1186/s12887-024-05374-x
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