Effectiveness of concentrated growth factors with or without grafting materials in maxillary sinus augmentation: a systematic review
Abstract Concentrated Growth Factor (CGF) is a highly effective biomaterial known for its ability to promote tissue regeneration. While it’s been studied extensively in intraoral procedures and bone grafting, its benefits in maxillary sinus lifting lack substantial evidence. This review aimed to eva...
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2024-10-01
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| Online Access: | https://doi.org/10.1186/s12903-024-04952-w |
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| author | Omar A. Al-Aroomi Yanjing Ou Karim A. Sakran Huachen Chen Yuxuan Lin Yan Gao Qin Cai Jiang Chen |
| author_facet | Omar A. Al-Aroomi Yanjing Ou Karim A. Sakran Huachen Chen Yuxuan Lin Yan Gao Qin Cai Jiang Chen |
| author_sort | Omar A. Al-Aroomi |
| collection | DOAJ |
| description | Abstract Concentrated Growth Factor (CGF) is a highly effective biomaterial known for its ability to promote tissue regeneration. While it’s been studied extensively in intraoral procedures and bone grafting, its benefits in maxillary sinus lifting lack substantial evidence. This review aimed to evaluate CGF’s effectiveness in maxillary sinus augmentation, focusing on clinical, radiographic, and histological outcomes. A comprehensive literature search was conducted across PubMed, Scopus, Web of Science, Google Scholar, and Cochrane Library databases using specific mesh terms and keywords and adhered to PRISMA guidelines. Studies up to March 2024 involving transcrestal or lateral maxillary sinus floor elevation with CGF, either alone or in combination with grafting materials, were included. Out of 783 publications, 13 studies met the eligibility criteria. The review assessed CGF’s role in minimizing postoperative complications, enhancing new bone formation, and improving implant survival. Despite data variability among studies, the majority reported that CGF positively influenced maxillary sinus augmentation outcomes. While more robust randomized clinical trials are required to draw definitive conclusions, initial results are promising, and the findings suggest that CGF utilization in maxillary sinus augmentation seems to enhance clinical outcomes by promoting vascularization and regeneration at the surgical sites and improving both the quality and quantity of newly formed sinus bone. Furthermore, it exhibits potential for improving postoperative sequelae and achieving high implant survival rates. |
| format | Article |
| id | doaj-art-e3daefcf41e440f5996e5efe58da9480 |
| institution | OA Journals |
| issn | 1472-6831 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Oral Health |
| spelling | doaj-art-e3daefcf41e440f5996e5efe58da94802025-08-20T02:12:03ZengBMCBMC Oral Health1472-68312024-10-0124111310.1186/s12903-024-04952-wEffectiveness of concentrated growth factors with or without grafting materials in maxillary sinus augmentation: a systematic reviewOmar A. Al-Aroomi0Yanjing Ou1Karim A. Sakran2Huachen Chen3Yuxuan Lin4Yan Gao5Qin Cai6Jiang Chen7Institute of Stomatology & Research Center of Dental and Craniofacial Implants, School and Hospital of Stomatology, Fujian Medical UniversityFujian Key Laboratory of Oral Diseases & Fujian Provincial Engineering Research Center of Oral Biomaterial & Stomatological Key Lab of Fujian College and University, School and Hospital of Stomatology, Fujian Medical UniversityDepartment of Oral and Maxillofacial Surgery, College of Dentistry, Ibb UniversityFujian Key Laboratory of Oral Diseases & Fujian Provincial Engineering Research Center of Oral Biomaterial & Stomatological Key Lab of Fujian College and University, School and Hospital of Stomatology, Fujian Medical UniversityInstitute of Stomatology & Research Center of Dental and Craniofacial Implants, School and Hospital of Stomatology, Fujian Medical UniversityInstitute of Stomatology & Research Center of Dental and Craniofacial Implants, School and Hospital of Stomatology, Fujian Medical UniversityInstitute of Stomatology & Research Center of Dental and Craniofacial Implants, School and Hospital of Stomatology, Fujian Medical UniversityInstitute of Stomatology & Research Center of Dental and Craniofacial Implants, School and Hospital of Stomatology, Fujian Medical UniversityAbstract Concentrated Growth Factor (CGF) is a highly effective biomaterial known for its ability to promote tissue regeneration. While it’s been studied extensively in intraoral procedures and bone grafting, its benefits in maxillary sinus lifting lack substantial evidence. This review aimed to evaluate CGF’s effectiveness in maxillary sinus augmentation, focusing on clinical, radiographic, and histological outcomes. A comprehensive literature search was conducted across PubMed, Scopus, Web of Science, Google Scholar, and Cochrane Library databases using specific mesh terms and keywords and adhered to PRISMA guidelines. Studies up to March 2024 involving transcrestal or lateral maxillary sinus floor elevation with CGF, either alone or in combination with grafting materials, were included. Out of 783 publications, 13 studies met the eligibility criteria. The review assessed CGF’s role in minimizing postoperative complications, enhancing new bone formation, and improving implant survival. Despite data variability among studies, the majority reported that CGF positively influenced maxillary sinus augmentation outcomes. While more robust randomized clinical trials are required to draw definitive conclusions, initial results are promising, and the findings suggest that CGF utilization in maxillary sinus augmentation seems to enhance clinical outcomes by promoting vascularization and regeneration at the surgical sites and improving both the quality and quantity of newly formed sinus bone. Furthermore, it exhibits potential for improving postoperative sequelae and achieving high implant survival rates.https://doi.org/10.1186/s12903-024-04952-wCGFMaxillary sinus augmentationDental implantBone graftSinus lift |
| spellingShingle | Omar A. Al-Aroomi Yanjing Ou Karim A. Sakran Huachen Chen Yuxuan Lin Yan Gao Qin Cai Jiang Chen Effectiveness of concentrated growth factors with or without grafting materials in maxillary sinus augmentation: a systematic review BMC Oral Health CGF Maxillary sinus augmentation Dental implant Bone graft Sinus lift |
| title | Effectiveness of concentrated growth factors with or without grafting materials in maxillary sinus augmentation: a systematic review |
| title_full | Effectiveness of concentrated growth factors with or without grafting materials in maxillary sinus augmentation: a systematic review |
| title_fullStr | Effectiveness of concentrated growth factors with or without grafting materials in maxillary sinus augmentation: a systematic review |
| title_full_unstemmed | Effectiveness of concentrated growth factors with or without grafting materials in maxillary sinus augmentation: a systematic review |
| title_short | Effectiveness of concentrated growth factors with or without grafting materials in maxillary sinus augmentation: a systematic review |
| title_sort | effectiveness of concentrated growth factors with or without grafting materials in maxillary sinus augmentation a systematic review |
| topic | CGF Maxillary sinus augmentation Dental implant Bone graft Sinus lift |
| url | https://doi.org/10.1186/s12903-024-04952-w |
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