Case report: Kinetics of viral load, immunoglobulins, and cytokines in a fatal case of Crimean-Congo hemorrhagic fever virus

Case report: Kinetics of viral load, immunoglobulins, and cytokines in a fatal case of Crimean-Congo hemorrhagic fever virus

A fatal case of Crimean-Congo hemorrhagic fever virus (CCHFV) was detected in Dakar, Senegal, West Africa, in April 2023. To elucidate the mechanisms involved in this outcome, the kinetics of viral load, immunoglobulins, and cytokines were assessed using RT-qPCR and ELISA. A high IL-6 titer, low IL-...

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Bibliographic Details
Main Authors: Moufid Mhamadi, Ousseynou Sene, Arfang Diamanka, Moundhir Mhamadi, Marie Pedapa Mendy, Andy Mahine Diouf, Mignane Ndiaye, Mamadou Aliou Barry, Samba Niang Sagne, Mahfouz Cissé Traoré, Amadou Alpha Sall, Gamou Fall, Ndongo Dia, Oumar Faye
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Virology
Subjects:
CCHFV
biomarkers
viremia
immunoglobulins
cytokines
severity
Online Access:https://www.frontiersin.org/articles/10.3389/fviro.2024.1498672/full
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