Relationship between Fractional Exhaled Nitric Oxide and Forced Oscillometric Technique in the Assessment of Asthma

Background: Fractional exhaled nitric oxide (FeNO) and forced oscillometric technique (FOT) represent noninvasive and sensitive tools for measuring airway inflammation and resistance, respectively, but the studies that use FeNO and FOT to assess patients with asthma until now are few. Objective: Thi...

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Main Authors: Amjed H. Abbas, Ahmed Hussein Jasim, Kareem Nasir Hussien Alesawi, Samir Sawadi Hammoud
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-12-01
Series:Medical Journal of Babylon
Subjects:
Online Access:https://doi.org/10.4103/MJBL.MJBL_1742_23
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author Amjed H. Abbas
Ahmed Hussein Jasim
Kareem Nasir Hussien Alesawi
Samir Sawadi Hammoud
author_facet Amjed H. Abbas
Ahmed Hussein Jasim
Kareem Nasir Hussien Alesawi
Samir Sawadi Hammoud
author_sort Amjed H. Abbas
collection DOAJ
description Background: Fractional exhaled nitric oxide (FeNO) and forced oscillometric technique (FOT) represent noninvasive and sensitive tools for measuring airway inflammation and resistance, respectively, but the studies that use FeNO and FOT to assess patients with asthma until now are few. Objective: This study aimed to evaluate the role of FeNO and FOT in the assessment of chronic asthma. Materials and Methods: This cross-sectional study involved 75 patients (10–70 years old) with chronic asthma who visited a private Spiro clinic in Al-Hilla City, Iraq, in the period from April 2022 to February 2023. They were examined by using the FeNO apparatus and FOT. Results: There were no significant differences between the patient and control group regarding age, gender, and body mass index. The study showed a significant relationship between expiratory flow rate and FeNO (P = 0.000). There was also a significant relationship between large airway resistance (Rrs) and FeNO (P = 0.008). In addition, there was a significant relationship between the resistance of small airways (as represented by Rrs19Hz) and FeNO level (P = 0.04). The study also found a significant relationship between reactance and FeNO level (P = 0.008). Conclusion: From the results, they conclude that the use of FOT and FeNO together gives considerable importance in the assessment of asthma.
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spelling doaj-art-e3cb29cbd97a4a7ea633832fe946dbbd2025-01-17T10:54:56ZengWolters Kluwer Medknow PublicationsMedical Journal of Babylon1812-156X2312-67602024-12-0121492893110.4103/MJBL.MJBL_1742_23Relationship between Fractional Exhaled Nitric Oxide and Forced Oscillometric Technique in the Assessment of AsthmaAmjed H. AbbasAhmed Hussein JasimKareem Nasir Hussien AlesawiSamir Sawadi HammoudBackground: Fractional exhaled nitric oxide (FeNO) and forced oscillometric technique (FOT) represent noninvasive and sensitive tools for measuring airway inflammation and resistance, respectively, but the studies that use FeNO and FOT to assess patients with asthma until now are few. Objective: This study aimed to evaluate the role of FeNO and FOT in the assessment of chronic asthma. Materials and Methods: This cross-sectional study involved 75 patients (10–70 years old) with chronic asthma who visited a private Spiro clinic in Al-Hilla City, Iraq, in the period from April 2022 to February 2023. They were examined by using the FeNO apparatus and FOT. Results: There were no significant differences between the patient and control group regarding age, gender, and body mass index. The study showed a significant relationship between expiratory flow rate and FeNO (P = 0.000). There was also a significant relationship between large airway resistance (Rrs) and FeNO (P = 0.008). In addition, there was a significant relationship between the resistance of small airways (as represented by Rrs19Hz) and FeNO level (P = 0.04). The study also found a significant relationship between reactance and FeNO level (P = 0.008). Conclusion: From the results, they conclude that the use of FOT and FeNO together gives considerable importance in the assessment of asthma.https://doi.org/10.4103/MJBL.MJBL_1742_23chronic asthmafenofot
spellingShingle Amjed H. Abbas
Ahmed Hussein Jasim
Kareem Nasir Hussien Alesawi
Samir Sawadi Hammoud
Relationship between Fractional Exhaled Nitric Oxide and Forced Oscillometric Technique in the Assessment of Asthma
Medical Journal of Babylon
chronic asthma
feno
fot
title Relationship between Fractional Exhaled Nitric Oxide and Forced Oscillometric Technique in the Assessment of Asthma
title_full Relationship between Fractional Exhaled Nitric Oxide and Forced Oscillometric Technique in the Assessment of Asthma
title_fullStr Relationship between Fractional Exhaled Nitric Oxide and Forced Oscillometric Technique in the Assessment of Asthma
title_full_unstemmed Relationship between Fractional Exhaled Nitric Oxide and Forced Oscillometric Technique in the Assessment of Asthma
title_short Relationship between Fractional Exhaled Nitric Oxide and Forced Oscillometric Technique in the Assessment of Asthma
title_sort relationship between fractional exhaled nitric oxide and forced oscillometric technique in the assessment of asthma
topic chronic asthma
feno
fot
url https://doi.org/10.4103/MJBL.MJBL_1742_23
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