Rare case report: Liver metastasis from cervical adenocarcinoma presenting with cystic mass and obstructive jaundice

Liver metastases can originate from primary tumors in various organs; however, metastasis from cervical cancer to the liver is rare. Cervical cancer patients with distant metastases have a poor prognosis and reduced survival rates. This report describes a case of a cystic liver mass with obstructive...

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Main Authors: Jin Li, Xin Wei, Le Luo
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1558946/full
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author Jin Li
Xin Wei
Le Luo
author_facet Jin Li
Xin Wei
Le Luo
author_sort Jin Li
collection DOAJ
description Liver metastases can originate from primary tumors in various organs; however, metastasis from cervical cancer to the liver is rare. Cervical cancer patients with distant metastases have a poor prognosis and reduced survival rates. This report describes a case of a cystic liver mass with obstructive jaundice, observed four years after resection of cervical adenocarcinoma. The lesion lacked typical imaging characteristics of hepatic metastases and was initially suspected to be a biliary neoplasm. A contrast-enhanced, ultrasound-guided needle biopsy was performed to confirm the diagnosis. Histopathological analysis confirmed adenocarcinoma of the liver, and immunohistochemical staining suggested a uterine or adnexal origin. Considering the patient’s surgical history, the final diagnosis was liver metastasis originating from cervical adenocarcinoma. This report reviews relevant literature to discuss the clinical features, diagnostic challenges, and therapeutic strategies for liver metastasis of cervical cancer.
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publishDate 2025-05-01
publisher Frontiers Media S.A.
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series Frontiers in Oncology
spelling doaj-art-e3c7ce6b051b413788af68d1eda1f60f2025-08-20T03:21:50ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2025-05-011510.3389/fonc.2025.15589461558946Rare case report: Liver metastasis from cervical adenocarcinoma presenting with cystic mass and obstructive jaundiceJin Li0Xin Wei1Le Luo2Department of Ultrasound, Deyang People’s Hospital, Deyang, Sichuan, ChinaDepartment of Ultrasound, Deyang People’s Hospital, Deyang, Sichuan, ChinaMedical Records Statistics Management Section, Deyang People’s Hospital, Deyang, Sichuan, ChinaLiver metastases can originate from primary tumors in various organs; however, metastasis from cervical cancer to the liver is rare. Cervical cancer patients with distant metastases have a poor prognosis and reduced survival rates. This report describes a case of a cystic liver mass with obstructive jaundice, observed four years after resection of cervical adenocarcinoma. The lesion lacked typical imaging characteristics of hepatic metastases and was initially suspected to be a biliary neoplasm. A contrast-enhanced, ultrasound-guided needle biopsy was performed to confirm the diagnosis. Histopathological analysis confirmed adenocarcinoma of the liver, and immunohistochemical staining suggested a uterine or adnexal origin. Considering the patient’s surgical history, the final diagnosis was liver metastasis originating from cervical adenocarcinoma. This report reviews relevant literature to discuss the clinical features, diagnostic challenges, and therapeutic strategies for liver metastasis of cervical cancer.https://www.frontiersin.org/articles/10.3389/fonc.2025.1558946/fullliver metastaseshepatic cystic neoplasmscervical cancercontrast-enhanced ultrasoundcase report
spellingShingle Jin Li
Xin Wei
Le Luo
Rare case report: Liver metastasis from cervical adenocarcinoma presenting with cystic mass and obstructive jaundice
Frontiers in Oncology
liver metastases
hepatic cystic neoplasms
cervical cancer
contrast-enhanced ultrasound
case report
title Rare case report: Liver metastasis from cervical adenocarcinoma presenting with cystic mass and obstructive jaundice
title_full Rare case report: Liver metastasis from cervical adenocarcinoma presenting with cystic mass and obstructive jaundice
title_fullStr Rare case report: Liver metastasis from cervical adenocarcinoma presenting with cystic mass and obstructive jaundice
title_full_unstemmed Rare case report: Liver metastasis from cervical adenocarcinoma presenting with cystic mass and obstructive jaundice
title_short Rare case report: Liver metastasis from cervical adenocarcinoma presenting with cystic mass and obstructive jaundice
title_sort rare case report liver metastasis from cervical adenocarcinoma presenting with cystic mass and obstructive jaundice
topic liver metastases
hepatic cystic neoplasms
cervical cancer
contrast-enhanced ultrasound
case report
url https://www.frontiersin.org/articles/10.3389/fonc.2025.1558946/full
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AT xinwei rarecasereportlivermetastasisfromcervicaladenocarcinomapresentingwithcysticmassandobstructivejaundice
AT leluo rarecasereportlivermetastasisfromcervicaladenocarcinomapresentingwithcysticmassandobstructivejaundice