Silent Thyroiditis Presented as Transient Hypothyroidism during Pregnancy: A Case Report
Silent thyroiditis during pregnancy is an under-recognized clinical condition and a rare case, often manifesting as transient hypothyroidism. We report a 23-year-old woman at 8 weeks of gestation who presented with newly diagnosed hypothyroidism [TSH = 85 mIU/L (0.4–4.5), FT4 = 0.4 ng/dL (0.7–2.5),...
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Tehran University of Medical Sciences
2025-04-01
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| Series: | Case Reports in Clinical Practice |
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| Online Access: | https://crcp.tums.ac.ir/index.php/crcp/article/view/1012 |
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| author | Mahmoud Ali Kaykhaei Shahin Nosratzehi |
| author_facet | Mahmoud Ali Kaykhaei Shahin Nosratzehi |
| author_sort | Mahmoud Ali Kaykhaei |
| collection | DOAJ |
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Silent thyroiditis during pregnancy is an under-recognized clinical condition and a rare case, often manifesting as transient hypothyroidism. We report a 23-year-old woman at 8 weeks of gestation who presented with newly diagnosed hypothyroidism [TSH = 85 mIU/L (0.4–4.5), FT4 = 0.4 ng/dL (0.7–2.5), and anti-TPO = 78 IU/mL (up
to 16)]. Thyroid function tests had been normal eight months prior. Levothyroxine (LT4) therapy was initiated, restoring euthyroidism. Treatment was discontinued postpartum, and the patient maintained normal thyroid function for over one year. Our case is unique in that silent thyroiditis occurred unusually early in pregnancy
and differed from the more common postpartum cases. Silent thyroiditis should be considered in pregnancy-related hypothyroidism, particularly when prior thyroid function was normal. Prompt diagnosis and treatment can prevent adverse maternal and fetal outcomes.
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| format | Article |
| id | doaj-art-e3c4f4da385b4376a4e414c711a30c0c |
| institution | OA Journals |
| issn | 2538-2683 2538-2691 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Case Reports in Clinical Practice |
| spelling | doaj-art-e3c4f4da385b4376a4e414c711a30c0c2025-08-20T01:51:13ZengTehran University of Medical SciencesCase Reports in Clinical Practice2538-26832538-26912025-04-019510.18502/crcp.v9i5.18453Silent Thyroiditis Presented as Transient Hypothyroidism during Pregnancy: A Case ReportMahmoud Ali Kaykhaei0Shahin Nosratzehi1Health Promotion Research Center, Zahedan University of Medical Sciences, Zahedan, Iran.Department of Internal Medicine, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran. Silent thyroiditis during pregnancy is an under-recognized clinical condition and a rare case, often manifesting as transient hypothyroidism. We report a 23-year-old woman at 8 weeks of gestation who presented with newly diagnosed hypothyroidism [TSH = 85 mIU/L (0.4–4.5), FT4 = 0.4 ng/dL (0.7–2.5), and anti-TPO = 78 IU/mL (up to 16)]. Thyroid function tests had been normal eight months prior. Levothyroxine (LT4) therapy was initiated, restoring euthyroidism. Treatment was discontinued postpartum, and the patient maintained normal thyroid function for over one year. Our case is unique in that silent thyroiditis occurred unusually early in pregnancy and differed from the more common postpartum cases. Silent thyroiditis should be considered in pregnancy-related hypothyroidism, particularly when prior thyroid function was normal. Prompt diagnosis and treatment can prevent adverse maternal and fetal outcomes. https://crcp.tums.ac.ir/index.php/crcp/article/view/1012HypothyroidismPregnancyThyroiditisTransientThyroid dysfunction |
| spellingShingle | Mahmoud Ali Kaykhaei Shahin Nosratzehi Silent Thyroiditis Presented as Transient Hypothyroidism during Pregnancy: A Case Report Case Reports in Clinical Practice Hypothyroidism Pregnancy Thyroiditis Transient Thyroid dysfunction |
| title | Silent Thyroiditis Presented as Transient Hypothyroidism during Pregnancy: A Case Report |
| title_full | Silent Thyroiditis Presented as Transient Hypothyroidism during Pregnancy: A Case Report |
| title_fullStr | Silent Thyroiditis Presented as Transient Hypothyroidism during Pregnancy: A Case Report |
| title_full_unstemmed | Silent Thyroiditis Presented as Transient Hypothyroidism during Pregnancy: A Case Report |
| title_short | Silent Thyroiditis Presented as Transient Hypothyroidism during Pregnancy: A Case Report |
| title_sort | silent thyroiditis presented as transient hypothyroidism during pregnancy a case report |
| topic | Hypothyroidism Pregnancy Thyroiditis Transient Thyroid dysfunction |
| url | https://crcp.tums.ac.ir/index.php/crcp/article/view/1012 |
| work_keys_str_mv | AT mahmoudalikaykhaei silentthyroiditispresentedastransienthypothyroidismduringpregnancyacasereport AT shahinnosratzehi silentthyroiditispresentedastransienthypothyroidismduringpregnancyacasereport |