Severe valvular toxicity and pericarditis early after radiation therapy in a patient treated for Hodgkin's lymphoma
Hodgkin's disease can be cured in most cases by radiotherapy. However, it can increase the risk of cardiotoxicity. Here, we report a patient with Hodgkin's disease and superior vena cava syndrome who was treated with chemotherapy in combination with radiotherapy. Four months after t...
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| Format: | Article |
| Language: | English |
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Hacettepe University Institute of Child Health
2010-08-01
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| Series: | The Turkish Journal of Pediatrics |
| Online Access: | https://turkjpediatr.org/article/view/5007 |
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| _version_ | 1850237139639336960 |
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| author | Asghar Ramyar Masoud Shafiei Kasra Moazzami Nima Rezaei |
| author_facet | Asghar Ramyar Masoud Shafiei Kasra Moazzami Nima Rezaei |
| author_sort | Asghar Ramyar |
| collection | DOAJ |
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Hodgkin's disease can be cured in most cases by radiotherapy. However, it can increase the risk of cardiotoxicity. Here, we report a patient with Hodgkin's disease and superior vena cava syndrome who was treated with chemotherapy in combination with radiotherapy. Four months after the initiation of this therapy, she developed progressive dyspnea. Pleural and pericardial effusion, severe mitral regurgitation, moderate aortic insufficiency, and mild tricuspid regurgitation were detected in echocardiography, which suggested heart failure. The patient was then treated with intrapericardial drainage and received dopamine and diuretics for congestive heart failure; she responded well to this treatment and was discharged in good condition. After high-dose mediastinal radiation, cardiologic screening is recommended in order to identify patients with radiation-induced heart disease and to assess their need for treatment and follow-up.
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| format | Article |
| id | doaj-art-e3c1a144f86a4a5d94a817c1d1d18496 |
| institution | OA Journals |
| issn | 0041-4301 2791-6421 |
| language | English |
| publishDate | 2010-08-01 |
| publisher | Hacettepe University Institute of Child Health |
| record_format | Article |
| series | The Turkish Journal of Pediatrics |
| spelling | doaj-art-e3c1a144f86a4a5d94a817c1d1d184962025-08-20T02:01:49ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212010-08-01524Severe valvular toxicity and pericarditis early after radiation therapy in a patient treated for Hodgkin's lymphomaAsghar Ramyar0Masoud ShafieiKasra MoazzamiNima RezaeiDepartment of Pediatrics, Pediatrics Center of Excellence, Children's Medical Center, Iran. Hodgkin's disease can be cured in most cases by radiotherapy. However, it can increase the risk of cardiotoxicity. Here, we report a patient with Hodgkin's disease and superior vena cava syndrome who was treated with chemotherapy in combination with radiotherapy. Four months after the initiation of this therapy, she developed progressive dyspnea. Pleural and pericardial effusion, severe mitral regurgitation, moderate aortic insufficiency, and mild tricuspid regurgitation were detected in echocardiography, which suggested heart failure. The patient was then treated with intrapericardial drainage and received dopamine and diuretics for congestive heart failure; she responded well to this treatment and was discharged in good condition. After high-dose mediastinal radiation, cardiologic screening is recommended in order to identify patients with radiation-induced heart disease and to assess their need for treatment and follow-up. https://turkjpediatr.org/article/view/5007 |
| spellingShingle | Asghar Ramyar Masoud Shafiei Kasra Moazzami Nima Rezaei Severe valvular toxicity and pericarditis early after radiation therapy in a patient treated for Hodgkin's lymphoma The Turkish Journal of Pediatrics |
| title | Severe valvular toxicity and pericarditis early after radiation therapy in a patient treated for Hodgkin's lymphoma |
| title_full | Severe valvular toxicity and pericarditis early after radiation therapy in a patient treated for Hodgkin's lymphoma |
| title_fullStr | Severe valvular toxicity and pericarditis early after radiation therapy in a patient treated for Hodgkin's lymphoma |
| title_full_unstemmed | Severe valvular toxicity and pericarditis early after radiation therapy in a patient treated for Hodgkin's lymphoma |
| title_short | Severe valvular toxicity and pericarditis early after radiation therapy in a patient treated for Hodgkin's lymphoma |
| title_sort | severe valvular toxicity and pericarditis early after radiation therapy in a patient treated for hodgkin s lymphoma |
| url | https://turkjpediatr.org/article/view/5007 |
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