ASSESSMENT OF MARKERS OF HEMOSTASIS AND ENDOTHELIAL DYSFUNCTION IN PATIENTS WITH PROGRESSIVE OBLITERATING LOWER LIMB ATHEROSCLEROSIS
We performed a comprehensive evaluation of the hemostatic system and markers of endothelial dysfunction in patients with obliterating lower limb atherosclerosis involving the femoral-popliteal-tibial segment. Progressive course of obliterating atherosclerosis is associated with hypercoagulation (inc...
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| Format: | Article |
| Language: | Russian |
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Private institution educational organization of higher education "Medical University "ReaViz"
2020-11-01
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| Series: | Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье |
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| Online Access: | https://vestnik.reaviz.ru/jour/article/view/68 |
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| _version_ | 1850050368277315584 |
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| author | E. A. Korymasov E. P. Krivoshchekov A. V. Kazantsev D. L. Pribytkov P. N. Zolotarev |
| author_facet | E. A. Korymasov E. P. Krivoshchekov A. V. Kazantsev D. L. Pribytkov P. N. Zolotarev |
| author_sort | E. A. Korymasov |
| collection | DOAJ |
| description | We performed a comprehensive evaluation of the hemostatic system and markers of endothelial dysfunction in patients with obliterating lower limb atherosclerosis involving the femoral-popliteal-tibial segment. Progressive course of obliterating atherosclerosis is associated with hypercoagulation (increased platelet aggregation activity, shortened aPTT, PT, TT, increased levels of fibrinogen, SFMCs, and D-dimer), as well as with endothelial dysfunction (increased levels of endothelin-1, von Willebrand factor, homocysteine, and Creactive protein). |
| format | Article |
| id | doaj-art-e3bfad60d43f40e5ad450474a116673b |
| institution | DOAJ |
| issn | 2226-762X 2782-1579 |
| language | Russian |
| publishDate | 2020-11-01 |
| publisher | Private institution educational organization of higher education "Medical University "ReaViz" |
| record_format | Article |
| series | Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье |
| spelling | doaj-art-e3bfad60d43f40e5ad450474a116673b2025-08-20T02:53:29ZrusPrivate institution educational organization of higher education "Medical University "ReaViz"Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье2226-762X2782-15792020-11-010313814565ASSESSMENT OF MARKERS OF HEMOSTASIS AND ENDOTHELIAL DYSFUNCTION IN PATIENTS WITH PROGRESSIVE OBLITERATING LOWER LIMB ATHEROSCLEROSISE. A. Korymasov0E. P. Krivoshchekov1A. V. Kazantsev2D. L. Pribytkov3P. N. Zolotarev4Federal State Budgetary Institution of Higher Education ‘Samara State Medical University’, Ministry of Health of the Russian FederationFederal State Budgetary Institution of Higher Education ‘Samara State Medical University’, Ministry of Health of the Russian FederationFederal State Budgetary Institution of Higher Education ‘Samara State Medical University’, Ministry of Health of the Russian FederationState Budgetary Healthcare Institution ‘V.D. Seredavin Samara Regional Clinical Hospital‘Private Institution of Higher Education ‘Medical University ‘Reaviz’We performed a comprehensive evaluation of the hemostatic system and markers of endothelial dysfunction in patients with obliterating lower limb atherosclerosis involving the femoral-popliteal-tibial segment. Progressive course of obliterating atherosclerosis is associated with hypercoagulation (increased platelet aggregation activity, shortened aPTT, PT, TT, increased levels of fibrinogen, SFMCs, and D-dimer), as well as with endothelial dysfunction (increased levels of endothelin-1, von Willebrand factor, homocysteine, and Creactive protein).https://vestnik.reaviz.ru/jour/article/view/68lower limb atherosclerosishemostatic systemhyperhomocysteinemiaendothelial dysfunction |
| spellingShingle | E. A. Korymasov E. P. Krivoshchekov A. V. Kazantsev D. L. Pribytkov P. N. Zolotarev ASSESSMENT OF MARKERS OF HEMOSTASIS AND ENDOTHELIAL DYSFUNCTION IN PATIENTS WITH PROGRESSIVE OBLITERATING LOWER LIMB ATHEROSCLEROSIS Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье lower limb atherosclerosis hemostatic system hyperhomocysteinemia endothelial dysfunction |
| title | ASSESSMENT OF MARKERS OF HEMOSTASIS AND ENDOTHELIAL DYSFUNCTION IN PATIENTS WITH PROGRESSIVE OBLITERATING LOWER LIMB ATHEROSCLEROSIS |
| title_full | ASSESSMENT OF MARKERS OF HEMOSTASIS AND ENDOTHELIAL DYSFUNCTION IN PATIENTS WITH PROGRESSIVE OBLITERATING LOWER LIMB ATHEROSCLEROSIS |
| title_fullStr | ASSESSMENT OF MARKERS OF HEMOSTASIS AND ENDOTHELIAL DYSFUNCTION IN PATIENTS WITH PROGRESSIVE OBLITERATING LOWER LIMB ATHEROSCLEROSIS |
| title_full_unstemmed | ASSESSMENT OF MARKERS OF HEMOSTASIS AND ENDOTHELIAL DYSFUNCTION IN PATIENTS WITH PROGRESSIVE OBLITERATING LOWER LIMB ATHEROSCLEROSIS |
| title_short | ASSESSMENT OF MARKERS OF HEMOSTASIS AND ENDOTHELIAL DYSFUNCTION IN PATIENTS WITH PROGRESSIVE OBLITERATING LOWER LIMB ATHEROSCLEROSIS |
| title_sort | assessment of markers of hemostasis and endothelial dysfunction in patients with progressive obliterating lower limb atherosclerosis |
| topic | lower limb atherosclerosis hemostatic system hyperhomocysteinemia endothelial dysfunction |
| url | https://vestnik.reaviz.ru/jour/article/view/68 |
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