Electrical Stimulation Therapy – Dedicated to the Perfect Plastic Repair

Abstract Tissue repair and reconstruction are a clinical difficulty. Bioelectricity has been identified as a critical factor in supporting tissue and cell viability during the repair process, presenting substantial potential for clinical application. This review delves into various sources of electr...

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Main Authors: Kexin Deng, Ruizeng Luo, Ying Chen, Xiaoqiang Liu, Yuanyin Xi, Muhammad Usman, Xupin Jiang, Zhou Li, Jiaping Zhang
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:Advanced Science
Subjects:
Online Access:https://doi.org/10.1002/advs.202409884
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author Kexin Deng
Ruizeng Luo
Ying Chen
Xiaoqiang Liu
Yuanyin Xi
Muhammad Usman
Xupin Jiang
Zhou Li
Jiaping Zhang
author_facet Kexin Deng
Ruizeng Luo
Ying Chen
Xiaoqiang Liu
Yuanyin Xi
Muhammad Usman
Xupin Jiang
Zhou Li
Jiaping Zhang
author_sort Kexin Deng
collection DOAJ
description Abstract Tissue repair and reconstruction are a clinical difficulty. Bioelectricity has been identified as a critical factor in supporting tissue and cell viability during the repair process, presenting substantial potential for clinical application. This review delves into various sources of electrical stimulation and identifies appropriate electrode materials for clinical use. It also highlights the biological mechanisms of electrical stimulation at both the subcellular and cellular levels, elucidating how these interactions facilitate the repair and regeneration processes across different organs. Moreover, specific electrode materials and stimulation sources are outlined, detailing their impact on cellular activity. The future development trends are projected from two perspectives: the optimization of equipment performance and the fulfillment of clinical demands, focusing on the feasibility, safety, and cost‐effectiveness of technologies.
format Article
id doaj-art-e3bef0723ede4e809792babb8b5b637a
institution Kabale University
issn 2198-3844
language English
publishDate 2025-06-01
publisher Wiley
record_format Article
series Advanced Science
spelling doaj-art-e3bef0723ede4e809792babb8b5b637a2025-08-20T03:28:00ZengWileyAdvanced Science2198-38442025-06-011224n/an/a10.1002/advs.202409884Electrical Stimulation Therapy – Dedicated to the Perfect Plastic RepairKexin Deng0Ruizeng Luo1Ying Chen2Xiaoqiang Liu3Yuanyin Xi4Muhammad Usman5Xupin Jiang6Zhou Li7Jiaping Zhang8Department of Plastic Surgery State Key Laboratory of Trauma and Chemical Poisoning Southwest Hospital Third Military Medical University (Army Medical University) Chongqing 400038 ChinaBeijing Institute of Nanoenergy and Nanosystems Chinese Academy of Sciences Beijing 101400 ChinaDepartment of Plastic Surgery State Key Laboratory of Trauma and Chemical Poisoning Southwest Hospital Third Military Medical University (Army Medical University) Chongqing 400038 ChinaDepartment of Plastic Surgery State Key Laboratory of Trauma and Chemical Poisoning Southwest Hospital Third Military Medical University (Army Medical University) Chongqing 400038 ChinaA Breast Disease Center Southwest Hospital Third Military Medical University (Army Medical University) Chongqing 400038 ChinaDepartment of Plastic Surgery and Burn Central Hospital Affiliated with Chongqing University of Technology Chongqing 400054 P.R. ChinaDepartment of Plastic Surgery State Key Laboratory of Trauma and Chemical Poisoning Southwest Hospital Third Military Medical University (Army Medical University) Chongqing 400038 ChinaDepartment of Plastic Surgery State Key Laboratory of Trauma and Chemical Poisoning Southwest Hospital Third Military Medical University (Army Medical University) Chongqing 400038 ChinaDepartment of Plastic Surgery State Key Laboratory of Trauma and Chemical Poisoning Southwest Hospital Third Military Medical University (Army Medical University) Chongqing 400038 ChinaAbstract Tissue repair and reconstruction are a clinical difficulty. Bioelectricity has been identified as a critical factor in supporting tissue and cell viability during the repair process, presenting substantial potential for clinical application. This review delves into various sources of electrical stimulation and identifies appropriate electrode materials for clinical use. It also highlights the biological mechanisms of electrical stimulation at both the subcellular and cellular levels, elucidating how these interactions facilitate the repair and regeneration processes across different organs. Moreover, specific electrode materials and stimulation sources are outlined, detailing their impact on cellular activity. The future development trends are projected from two perspectives: the optimization of equipment performance and the fulfillment of clinical demands, focusing on the feasibility, safety, and cost‐effectiveness of technologies.https://doi.org/10.1002/advs.202409884cellular activityclinical therapyelectrical stimulationnanogeneratortissue repair
spellingShingle Kexin Deng
Ruizeng Luo
Ying Chen
Xiaoqiang Liu
Yuanyin Xi
Muhammad Usman
Xupin Jiang
Zhou Li
Jiaping Zhang
Electrical Stimulation Therapy – Dedicated to the Perfect Plastic Repair
Advanced Science
cellular activity
clinical therapy
electrical stimulation
nanogenerator
tissue repair
title Electrical Stimulation Therapy – Dedicated to the Perfect Plastic Repair
title_full Electrical Stimulation Therapy – Dedicated to the Perfect Plastic Repair
title_fullStr Electrical Stimulation Therapy – Dedicated to the Perfect Plastic Repair
title_full_unstemmed Electrical Stimulation Therapy – Dedicated to the Perfect Plastic Repair
title_short Electrical Stimulation Therapy – Dedicated to the Perfect Plastic Repair
title_sort electrical stimulation therapy dedicated to the perfect plastic repair
topic cellular activity
clinical therapy
electrical stimulation
nanogenerator
tissue repair
url https://doi.org/10.1002/advs.202409884
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AT ruizengluo electricalstimulationtherapydedicatedtotheperfectplasticrepair
AT yingchen electricalstimulationtherapydedicatedtotheperfectplasticrepair
AT xiaoqiangliu electricalstimulationtherapydedicatedtotheperfectplasticrepair
AT yuanyinxi electricalstimulationtherapydedicatedtotheperfectplasticrepair
AT muhammadusman electricalstimulationtherapydedicatedtotheperfectplasticrepair
AT xupinjiang electricalstimulationtherapydedicatedtotheperfectplasticrepair
AT zhouli electricalstimulationtherapydedicatedtotheperfectplasticrepair
AT jiapingzhang electricalstimulationtherapydedicatedtotheperfectplasticrepair