Synthesis and biological properties of hemin conjugates with unprotected peptides.
Arginine-containing peptides consisted of 3- and 13- amino acids residues, namely RGD and [5Ala]-indolicidine were synthetized. Monosubstituted hemin derivatives modificated by RGD, [5Ala]-indolicidine and gramicidine S were obtained. Biocide activity and low toxicity of obtained conjugates was show...
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| Format: | Article |
| Language: | Russian |
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MIREA - Russian Technological University
2010-10-01
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| Series: | Тонкие химические технологии |
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| Online Access: | https://www.finechem-mirea.ru/jour/article/view/934 |
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| author | S. A. Okorochenkov E. A. Bistrova E. M. Pavlova G. A. Zheltukhina V. E. Nebolsin |
| author_facet | S. A. Okorochenkov E. A. Bistrova E. M. Pavlova G. A. Zheltukhina V. E. Nebolsin |
| author_sort | S. A. Okorochenkov |
| collection | DOAJ |
| description | Arginine-containing peptides consisted of 3- and 13- amino acids residues, namely RGD and [5Ala]-indolicidine were synthetized. Monosubstituted hemin derivatives modificated by RGD, [5Ala]-indolicidine and gramicidine S were obtained. Biocide activity and low toxicity of obtained conjugates was shown. |
| format | Article |
| id | doaj-art-e3bb959457a849b0ae77ff868bffa132 |
| institution | Kabale University |
| issn | 2410-6593 2686-7575 |
| language | Russian |
| publishDate | 2010-10-01 |
| publisher | MIREA - Russian Technological University |
| record_format | Article |
| series | Тонкие химические технологии |
| spelling | doaj-art-e3bb959457a849b0ae77ff868bffa1322025-08-20T03:56:24ZrusMIREA - Russian Technological UniversityТонкие химические технологии2410-65932686-75752010-10-01557181928Synthesis and biological properties of hemin conjugates with unprotected peptides.S. A. Okorochenkov0E. A. Bistrova1E. M. Pavlova2G. A. Zheltukhina3V. E. Nebolsin4МИТХТ им. М.В. Ломоносова, 119571, Москва, пр-т Вернадского, д. 86МИТХТ им. М.В. Ломоносова, 119571, Москва, пр-т Вернадского, д. 86МИТХТ им. М.В. Ломоносова, 119571, Москва, пр-т Вернадского, д. 86МИТХТ им. М.В. Ломоносова, 119571, Москва, пр-т Вернадского, д. 86ООО «Фарминтерпрайсез»Arginine-containing peptides consisted of 3- and 13- amino acids residues, namely RGD and [5Ala]-indolicidine were synthetized. Monosubstituted hemin derivatives modificated by RGD, [5Ala]-indolicidine and gramicidine S were obtained. Biocide activity and low toxicity of obtained conjugates was shown.https://www.finechem-mirea.ru/jour/article/view/934heminantimicrobial peptidesbiocide activity |
| spellingShingle | S. A. Okorochenkov E. A. Bistrova E. M. Pavlova G. A. Zheltukhina V. E. Nebolsin Synthesis and biological properties of hemin conjugates with unprotected peptides. Тонкие химические технологии hemin antimicrobial peptides biocide activity |
| title | Synthesis and biological properties of hemin conjugates with unprotected peptides. |
| title_full | Synthesis and biological properties of hemin conjugates with unprotected peptides. |
| title_fullStr | Synthesis and biological properties of hemin conjugates with unprotected peptides. |
| title_full_unstemmed | Synthesis and biological properties of hemin conjugates with unprotected peptides. |
| title_short | Synthesis and biological properties of hemin conjugates with unprotected peptides. |
| title_sort | synthesis and biological properties of hemin conjugates with unprotected peptides |
| topic | hemin antimicrobial peptides biocide activity |
| url | https://www.finechem-mirea.ru/jour/article/view/934 |
| work_keys_str_mv | AT saokorochenkov synthesisandbiologicalpropertiesofheminconjugateswithunprotectedpeptides AT eabistrova synthesisandbiologicalpropertiesofheminconjugateswithunprotectedpeptides AT empavlova synthesisandbiologicalpropertiesofheminconjugateswithunprotectedpeptides AT gazheltukhina synthesisandbiologicalpropertiesofheminconjugateswithunprotectedpeptides AT venebolsin synthesisandbiologicalpropertiesofheminconjugateswithunprotectedpeptides |