The effects of end-tidal controlled low-flow anesthesia on anesthetic agent consumption in elective surgeries: randomized controlled trial

Abstract Purpose The environmental impact and cost of volatile anesthetics are significant concerns in modern anesthesia. Automated end-tidal control systems aim to optimize anesthetic delivery by reducing waste and improving efficiency. This study compared the effectiveness of end-tidal controlled...

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Main Authors: Elzem Sen, Suleyman Ganidaglı, Ayse Mizrak, Berna Kaya Ugur, Mehmet Cesur, Fahrettin Yildiz, Lutfiye Pirbudak
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Anesthesiology
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Online Access:https://doi.org/10.1186/s12871-025-03051-9
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author Elzem Sen
Suleyman Ganidaglı
Ayse Mizrak
Berna Kaya Ugur
Mehmet Cesur
Fahrettin Yildiz
Lutfiye Pirbudak
author_facet Elzem Sen
Suleyman Ganidaglı
Ayse Mizrak
Berna Kaya Ugur
Mehmet Cesur
Fahrettin Yildiz
Lutfiye Pirbudak
author_sort Elzem Sen
collection DOAJ
description Abstract Purpose The environmental impact and cost of volatile anesthetics are significant concerns in modern anesthesia. Automated end-tidal control systems aim to optimize anesthetic delivery by reducing waste and improving efficiency. This study compared the effectiveness of end-tidal controlled (EtControl) low-flow anesthesia to manually controlled (MC) low-flow anesthesia in elective surgeries. Design A randomized controlled trial. Methods This study was conducted with 132 ASA Class I–II patients undergoing elective surgeries under general anesthesia. Patients were randomly assigned to the EtControl (n = 66) or MC (n = 66) groups. The primary outcomes included anesthetic agent consumption (mL). Findings Anesthetic consumption was similar between the EtControl group (17.9 ± 2.63 mL) and the MC group (18.45 ± 2.44 mL) (p = 0.07). The rate of anesthetic consumption per minute was also comparable (0.120 mL/min vs. 0.127 mL/min; p = 0.514). Conclusions EtControl and MC methods provide comparable safety and sevoflurane consumption during low-flow anesthesia. However, EtControl reduces manual adjustments, enhancing workflow efficiency and cost-effectiveness, with potential implications for reducing environmental impact.
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spelling doaj-art-e3b221fcf6084f8e92e7980c55823a342025-08-20T03:06:58ZengBMCBMC Anesthesiology1471-22532025-04-012511710.1186/s12871-025-03051-9The effects of end-tidal controlled low-flow anesthesia on anesthetic agent consumption in elective surgeries: randomized controlled trialElzem Sen0Suleyman Ganidaglı1Ayse Mizrak2Berna Kaya Ugur3Mehmet Cesur4Fahrettin Yildiz5Lutfiye Pirbudak6Department of Anesthesiology and Reanimation, University of GaziantepDepartment of Anesthesiology and Reanimation, University of GaziantepDepartment of Anesthesiology and Reanimation, University of GaziantepDepartment of Anesthesiology and Reanimation, University of GaziantepDepartment of Anesthesiology and Reanimation, University of GaziantepDepartment of General Surgery, University of GaziantepDepartment of Anesthesiology and Reanimation, University of GaziantepAbstract Purpose The environmental impact and cost of volatile anesthetics are significant concerns in modern anesthesia. Automated end-tidal control systems aim to optimize anesthetic delivery by reducing waste and improving efficiency. This study compared the effectiveness of end-tidal controlled (EtControl) low-flow anesthesia to manually controlled (MC) low-flow anesthesia in elective surgeries. Design A randomized controlled trial. Methods This study was conducted with 132 ASA Class I–II patients undergoing elective surgeries under general anesthesia. Patients were randomly assigned to the EtControl (n = 66) or MC (n = 66) groups. The primary outcomes included anesthetic agent consumption (mL). Findings Anesthetic consumption was similar between the EtControl group (17.9 ± 2.63 mL) and the MC group (18.45 ± 2.44 mL) (p = 0.07). The rate of anesthetic consumption per minute was also comparable (0.120 mL/min vs. 0.127 mL/min; p = 0.514). Conclusions EtControl and MC methods provide comparable safety and sevoflurane consumption during low-flow anesthesia. However, EtControl reduces manual adjustments, enhancing workflow efficiency and cost-effectiveness, with potential implications for reducing environmental impact.https://doi.org/10.1186/s12871-025-03051-9End-tidal controlledLow flow anesthesiaSevoflurane consumption
spellingShingle Elzem Sen
Suleyman Ganidaglı
Ayse Mizrak
Berna Kaya Ugur
Mehmet Cesur
Fahrettin Yildiz
Lutfiye Pirbudak
The effects of end-tidal controlled low-flow anesthesia on anesthetic agent consumption in elective surgeries: randomized controlled trial
BMC Anesthesiology
End-tidal controlled
Low flow anesthesia
Sevoflurane consumption
title The effects of end-tidal controlled low-flow anesthesia on anesthetic agent consumption in elective surgeries: randomized controlled trial
title_full The effects of end-tidal controlled low-flow anesthesia on anesthetic agent consumption in elective surgeries: randomized controlled trial
title_fullStr The effects of end-tidal controlled low-flow anesthesia on anesthetic agent consumption in elective surgeries: randomized controlled trial
title_full_unstemmed The effects of end-tidal controlled low-flow anesthesia on anesthetic agent consumption in elective surgeries: randomized controlled trial
title_short The effects of end-tidal controlled low-flow anesthesia on anesthetic agent consumption in elective surgeries: randomized controlled trial
title_sort effects of end tidal controlled low flow anesthesia on anesthetic agent consumption in elective surgeries randomized controlled trial
topic End-tidal controlled
Low flow anesthesia
Sevoflurane consumption
url https://doi.org/10.1186/s12871-025-03051-9
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