Real-world data on trastuzumab emtansine (TDM1) efficacy and safety: Results of a single-centre retrospective study of HER2-positive metastatic breast cancer patients

Real-world data on trastuzumab emtansine (TDM1) efficacy and safety: Results of a single-centre retrospective study of HER2-positive metastatic breast cancer patients

Abstract HER2-positive metastatic breast cancer (MBC) represents a challenging subtype of breast cancer, characterized by aggressive disease and poor clinical outcomes. Trastuzumab emtansine (TDM1), an antibody–drug conjugate combining trastuzumab and emtansine, has demonstrated efficacy in clinical...

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Main Authors: Anuj Gupta, Bipinesh Sansar, Bal Krishna Mishra, Aqusa Khan, Arpita Singh, Arvind Upadhyay, Zachariah Chowdhury, Shashikant Patne, Mayank Tripathi, Shreya Shukla, Satyendra Narayan Singh, Lincoln Pujari, Prashanth Giridhar, Ankita Rungta Kapoor, Arvind Suresh, Somnath Dey, Kunal Ranjan Vinayak, Neha Singh, Amit Kumar, Ankita Pal, Akhil Kapoor
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Her2 positive breast cancer
Trastuzumab emtansine (TDM1)
Real world data
Toxicity profile
Survival outcomes
Online Access:https://doi.org/10.1038/s41598-025-97923-2
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