Clinical observation of hemodialysis in the treatment of elderly type Ⅱ cardiorenal syndrome

Objective To compare the therapeutic effect of intermittent hemodialysis(IHD) vs.sustained low-efficiency hemodialysis(SLED) in elderly patients with type Ⅱ cardiorenal syndrome(CRS).Methods The clinical data of 62 elderly patients with type Ⅱ CRS in our hospital were retrospectively analyzed.All th...

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Main Authors: YANG Sheng-xi, MA Hong
Format: Article
Language:zho
Published: Editorial Department of Journal of Clinical Nephrology 2016-01-01
Series:Linchuang shenzangbing zazhi
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Online Access:http://www.lcszb.com/thesisDetails?columnId=57919498&Fpath=home&index=0
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Summary:Objective To compare the therapeutic effect of intermittent hemodialysis(IHD) vs.sustained low-efficiency hemodialysis(SLED) in elderly patients with type Ⅱ cardiorenal syndrome(CRS).Methods The clinical data of 62 elderly patients with type Ⅱ CRS in our hospital were retrospectively analyzed.All the patients accepted the hemodialysis with central venous catheters via the right femoral vein.According to the therapies,the patients were divided into two groups:IHD and SLED,with treatment for one week.During treatment,the patients were avoided to suffer excessive ultrafiltration.Before and after treatment,central venous pressure(CVP) and heart rate(HR) were measured,BUN and SCr were determined by Beckman Olympus AU2700 automatic biochemical Analyzer,N-terminal Pro Brain Natriuretic Peptide(NT-proBNP) was detected by ReLIA multifunctional immune detection instrument,and left ventricular ejection fraction(LVEF) and pulmonary arterial pressure(PAP) wer examined by Philips IE33 ultrasound scanner.Results There was significant difference in age between two groups(P<0.05).After treatment,BUN,SCr and NT-proBNP were all significantly reduced,and LVEF was significantly increased in both two groups(P<0.01).After treatment,HR,CVP and PAP were significantly reduced in IHD group(P<0.05).After treatment,HR,CVP and PAP were significantly reduced in SLED group(P<0.01).After treatment,HR,CVP and PAP were reduced in both two groups.Moreover,the changes in SLED group were reduced more obviously than in IHD group(P<0.01).Conclusions Both IHD and SLED have satisfactory treatment effects on elderly patients with type II CRS.SLED removes excess fluids in the body slowly and maintains the balance of internal environment It can remove the extra heart toxicity from kidney medulla continually,such as renin,and it also can keep the balance of water,electrolyte and pH.SLED can obtain more stable hemodynamics than IHD.For elderly patients with type E CRS,SLED can clear toxin quickly and adjust the unbalance of electrolyte and pH.Furthermore,SLED can obtain better hemodynamic stabilization and save the medical resources.In conclusion,the treatment effect of SLED is better than IHD.
ISSN:1671-2390