EFFECTS OF TEMPERATURE AND PERCENTAGE OF ORGANIC MODIFIER ON RETENTION AND SELECTIVITY IN RP-HPLC USING SOLVATION PARAMETER MODEL
Effects of temperature and percentage of organic modifier were studied on retention and selectivity in RP-HPLC using solvation parameter model. The system constants were determined by multiple linear regression analysis from experimental values in the retention factor for a group of different solute...
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| Format: | Article |
| Language: | English |
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University of Tehran
2003-12-01
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| Series: | Journal of Sciences, Islamic Republic of Iran |
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| Online Access: | https://jsciences.ut.ac.ir/article_35093_157fe4b3a13009fb1abcfe003b57cccd.pdf |
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| _version_ | 1849387352955289600 |
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| author | M.R. Hadjmohammadi |
| author_facet | M.R. Hadjmohammadi |
| author_sort | M.R. Hadjmohammadi |
| collection | DOAJ |
| description | Effects of temperature and percentage of organic modifier were studied on retention and selectivity in RP-HPLC using solvation parameter model. The system constants were determined by multiple linear regression analysis from experimental values in the retention factor for a group of different solutes with known descriptors by computer using the program SPSS/PC. The experimental results showed that the variation of percentages of organic modifier (5-20% V/V CH3CN) changes cavity formation (m = +3.55 to +2.53), dipole-dipole interactions (s = +0.62 to −0.64) and hydrogen-bond acidity (b = −2.41 to −3.27) terms. The variation of temperature (5-45°C) also changes cavity formation (m = +3.21 to +2.56) and dipole-dipole interactions (s = +0.34 to −0.22) terms. |
| format | Article |
| id | doaj-art-e3a88ceab9064f47832fc2f3344b1094 |
| institution | Kabale University |
| issn | 1016-1104 2345-6914 |
| language | English |
| publishDate | 2003-12-01 |
| publisher | University of Tehran |
| record_format | Article |
| series | Journal of Sciences, Islamic Republic of Iran |
| spelling | doaj-art-e3a88ceab9064f47832fc2f3344b10942025-08-20T03:53:51ZengUniversity of TehranJournal of Sciences, Islamic Republic of Iran1016-11042345-69142003-12-0114433734035093EFFECTS OF TEMPERATURE AND PERCENTAGE OF ORGANIC MODIFIER ON RETENTION AND SELECTIVITY IN RP-HPLC USING SOLVATION PARAMETER MODELM.R. Hadjmohammadi0Reversed-phase liquid chromatography; Solvation parameter modelEffects of temperature and percentage of organic modifier were studied on retention and selectivity in RP-HPLC using solvation parameter model. The system constants were determined by multiple linear regression analysis from experimental values in the retention factor for a group of different solutes with known descriptors by computer using the program SPSS/PC. The experimental results showed that the variation of percentages of organic modifier (5-20% V/V CH3CN) changes cavity formation (m = +3.55 to +2.53), dipole-dipole interactions (s = +0.62 to −0.64) and hydrogen-bond acidity (b = −2.41 to −3.27) terms. The variation of temperature (5-45°C) also changes cavity formation (m = +3.21 to +2.56) and dipole-dipole interactions (s = +0.34 to −0.22) terms.https://jsciences.ut.ac.ir/article_35093_157fe4b3a13009fb1abcfe003b57cccd.pdfreversed-phase liquid chromatographysolvation parameter model |
| spellingShingle | M.R. Hadjmohammadi EFFECTS OF TEMPERATURE AND PERCENTAGE OF ORGANIC MODIFIER ON RETENTION AND SELECTIVITY IN RP-HPLC USING SOLVATION PARAMETER MODEL Journal of Sciences, Islamic Republic of Iran reversed-phase liquid chromatography solvation parameter model |
| title | EFFECTS OF TEMPERATURE AND PERCENTAGE OF ORGANIC MODIFIER ON RETENTION
AND SELECTIVITY IN RP-HPLC USING
SOLVATION PARAMETER MODEL |
| title_full | EFFECTS OF TEMPERATURE AND PERCENTAGE OF ORGANIC MODIFIER ON RETENTION
AND SELECTIVITY IN RP-HPLC USING
SOLVATION PARAMETER MODEL |
| title_fullStr | EFFECTS OF TEMPERATURE AND PERCENTAGE OF ORGANIC MODIFIER ON RETENTION
AND SELECTIVITY IN RP-HPLC USING
SOLVATION PARAMETER MODEL |
| title_full_unstemmed | EFFECTS OF TEMPERATURE AND PERCENTAGE OF ORGANIC MODIFIER ON RETENTION
AND SELECTIVITY IN RP-HPLC USING
SOLVATION PARAMETER MODEL |
| title_short | EFFECTS OF TEMPERATURE AND PERCENTAGE OF ORGANIC MODIFIER ON RETENTION
AND SELECTIVITY IN RP-HPLC USING
SOLVATION PARAMETER MODEL |
| title_sort | effects of temperature and percentage of organic modifier on retention and selectivity in rp hplc using solvation parameter model |
| topic | reversed-phase liquid chromatography solvation parameter model |
| url | https://jsciences.ut.ac.ir/article_35093_157fe4b3a13009fb1abcfe003b57cccd.pdf |
| work_keys_str_mv | AT mrhadjmohammadi effectsoftemperatureandpercentageoforganicmodifieronretentionandselectivityinrphplcusingsolvationparametermodel |