A Case of Primary Breast Diffuse Large B-Cell Lymphoma Treated with Chemotherapy Followed by Elective Field Radiation Therapy: A Brief Treatment Pattern Review from a Radiation Oncologist’s Point of View

We here report a case of primary breast lymphoma (PBL). A 44-year-old woman presented with a painless mass in the right breast. Fine needle aspiration cytology and excisional biopsy were performed. Excisional biopsy revealed low grade lymphoma, which was subsequently confirmed with histopathology an...

Full description

Saved in:
Bibliographic Details
Main Authors: Kyu Chan Lee, Seung Heon Lee, KiHoon Sung, So Hyun Ahn, Jinho Choi, Seok Ho Lee, Jae Hoon Lee, Junshik Hong, Sang Hui Park
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Case Reports in Oncological Medicine
Online Access:http://dx.doi.org/10.1155/2015/907978
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1841524699336540160
author Kyu Chan Lee
Seung Heon Lee
KiHoon Sung
So Hyun Ahn
Jinho Choi
Seok Ho Lee
Jae Hoon Lee
Junshik Hong
Sang Hui Park
author_facet Kyu Chan Lee
Seung Heon Lee
KiHoon Sung
So Hyun Ahn
Jinho Choi
Seok Ho Lee
Jae Hoon Lee
Junshik Hong
Sang Hui Park
author_sort Kyu Chan Lee
collection DOAJ
description We here report a case of primary breast lymphoma (PBL). A 44-year-old woman presented with a painless mass in the right breast. Fine needle aspiration cytology and excisional biopsy were performed. Excisional biopsy revealed low grade lymphoma, which was subsequently confirmed with histopathology and diagnosed as diffuse large B-cell lymphoma (DLBCL). A chest computed tomography scan revealed a 3.5 cm sized breast mass with skin thickening and a small sized lymphadenopathy in the ipsilateral axilla. Radiation therapy including the right whole breast and ipsilateral axilla and supraclavicular lymph node was performed after the patient received four courses of R-CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisolone plus rituximab) chemotherapy. At the follow-up period of 42 months, the patient is surviving with no evidence of disease. No morbidities occurred in this patient during the follow-up period. We also briefly review the current practice pattern in PBL patients with DLBCL.
format Article
id doaj-art-e3a862ea293743c9956b1c23cc0cebed
institution Kabale University
issn 2090-6706
2090-6714
language English
publishDate 2015-01-01
publisher Wiley
record_format Article
series Case Reports in Oncological Medicine
spelling doaj-art-e3a862ea293743c9956b1c23cc0cebed2025-02-03T05:47:35ZengWileyCase Reports in Oncological Medicine2090-67062090-67142015-01-01201510.1155/2015/907978907978A Case of Primary Breast Diffuse Large B-Cell Lymphoma Treated with Chemotherapy Followed by Elective Field Radiation Therapy: A Brief Treatment Pattern Review from a Radiation Oncologist’s Point of ViewKyu Chan Lee0Seung Heon Lee1KiHoon Sung2So Hyun Ahn3Jinho Choi4Seok Ho Lee5Jae Hoon Lee6Junshik Hong7Sang Hui Park8Department of Radiation Oncology, Gil Medical Center, School of Medicine, Gachon University, Incheon 405-760, Republic of KoreaDepartment of Radiation Oncology, Gil Medical Center, School of Medicine, Gachon University, Incheon 405-760, Republic of KoreaDepartment of Radiation Oncology, Gil Medical Center, School of Medicine, Gachon University, Incheon 405-760, Republic of KoreaDepartment of Radiation Oncology, Gil Medical Center, School of Medicine, Gachon University, Incheon 405-760, Republic of KoreaDepartment of Radiation Oncology, Gil Medical Center, School of Medicine, Gachon University, Incheon 405-760, Republic of KoreaDepartment of Radiation Oncology, Gil Medical Center, School of Medicine, Gachon University, Incheon 405-760, Republic of KoreaDepartment of Internal Medicine, Gil Medical Center, School of Medicine, Gachon University, Incheon 405-760, Republic of KoreaDepartment of Internal Medicine, Gil Medical Center, School of Medicine, Gachon University, Incheon 405-760, Republic of KoreaDepartment of Pathology, Ewha Womans University School of Medicine, Seoul 158-710, Republic of KoreaWe here report a case of primary breast lymphoma (PBL). A 44-year-old woman presented with a painless mass in the right breast. Fine needle aspiration cytology and excisional biopsy were performed. Excisional biopsy revealed low grade lymphoma, which was subsequently confirmed with histopathology and diagnosed as diffuse large B-cell lymphoma (DLBCL). A chest computed tomography scan revealed a 3.5 cm sized breast mass with skin thickening and a small sized lymphadenopathy in the ipsilateral axilla. Radiation therapy including the right whole breast and ipsilateral axilla and supraclavicular lymph node was performed after the patient received four courses of R-CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisolone plus rituximab) chemotherapy. At the follow-up period of 42 months, the patient is surviving with no evidence of disease. No morbidities occurred in this patient during the follow-up period. We also briefly review the current practice pattern in PBL patients with DLBCL.http://dx.doi.org/10.1155/2015/907978
spellingShingle Kyu Chan Lee
Seung Heon Lee
KiHoon Sung
So Hyun Ahn
Jinho Choi
Seok Ho Lee
Jae Hoon Lee
Junshik Hong
Sang Hui Park
A Case of Primary Breast Diffuse Large B-Cell Lymphoma Treated with Chemotherapy Followed by Elective Field Radiation Therapy: A Brief Treatment Pattern Review from a Radiation Oncologist’s Point of View
Case Reports in Oncological Medicine
title A Case of Primary Breast Diffuse Large B-Cell Lymphoma Treated with Chemotherapy Followed by Elective Field Radiation Therapy: A Brief Treatment Pattern Review from a Radiation Oncologist’s Point of View
title_full A Case of Primary Breast Diffuse Large B-Cell Lymphoma Treated with Chemotherapy Followed by Elective Field Radiation Therapy: A Brief Treatment Pattern Review from a Radiation Oncologist’s Point of View
title_fullStr A Case of Primary Breast Diffuse Large B-Cell Lymphoma Treated with Chemotherapy Followed by Elective Field Radiation Therapy: A Brief Treatment Pattern Review from a Radiation Oncologist’s Point of View
title_full_unstemmed A Case of Primary Breast Diffuse Large B-Cell Lymphoma Treated with Chemotherapy Followed by Elective Field Radiation Therapy: A Brief Treatment Pattern Review from a Radiation Oncologist’s Point of View
title_short A Case of Primary Breast Diffuse Large B-Cell Lymphoma Treated with Chemotherapy Followed by Elective Field Radiation Therapy: A Brief Treatment Pattern Review from a Radiation Oncologist’s Point of View
title_sort case of primary breast diffuse large b cell lymphoma treated with chemotherapy followed by elective field radiation therapy a brief treatment pattern review from a radiation oncologist s point of view
url http://dx.doi.org/10.1155/2015/907978
work_keys_str_mv AT kyuchanlee acaseofprimarybreastdiffuselargebcelllymphomatreatedwithchemotherapyfollowedbyelectivefieldradiationtherapyabrieftreatmentpatternreviewfromaradiationoncologistspointofview
AT seungheonlee acaseofprimarybreastdiffuselargebcelllymphomatreatedwithchemotherapyfollowedbyelectivefieldradiationtherapyabrieftreatmentpatternreviewfromaradiationoncologistspointofview
AT kihoonsung acaseofprimarybreastdiffuselargebcelllymphomatreatedwithchemotherapyfollowedbyelectivefieldradiationtherapyabrieftreatmentpatternreviewfromaradiationoncologistspointofview
AT sohyunahn acaseofprimarybreastdiffuselargebcelllymphomatreatedwithchemotherapyfollowedbyelectivefieldradiationtherapyabrieftreatmentpatternreviewfromaradiationoncologistspointofview
AT jinhochoi acaseofprimarybreastdiffuselargebcelllymphomatreatedwithchemotherapyfollowedbyelectivefieldradiationtherapyabrieftreatmentpatternreviewfromaradiationoncologistspointofview
AT seokholee acaseofprimarybreastdiffuselargebcelllymphomatreatedwithchemotherapyfollowedbyelectivefieldradiationtherapyabrieftreatmentpatternreviewfromaradiationoncologistspointofview
AT jaehoonlee acaseofprimarybreastdiffuselargebcelllymphomatreatedwithchemotherapyfollowedbyelectivefieldradiationtherapyabrieftreatmentpatternreviewfromaradiationoncologistspointofview
AT junshikhong acaseofprimarybreastdiffuselargebcelllymphomatreatedwithchemotherapyfollowedbyelectivefieldradiationtherapyabrieftreatmentpatternreviewfromaradiationoncologistspointofview
AT sanghuipark acaseofprimarybreastdiffuselargebcelllymphomatreatedwithchemotherapyfollowedbyelectivefieldradiationtherapyabrieftreatmentpatternreviewfromaradiationoncologistspointofview
AT kyuchanlee caseofprimarybreastdiffuselargebcelllymphomatreatedwithchemotherapyfollowedbyelectivefieldradiationtherapyabrieftreatmentpatternreviewfromaradiationoncologistspointofview
AT seungheonlee caseofprimarybreastdiffuselargebcelllymphomatreatedwithchemotherapyfollowedbyelectivefieldradiationtherapyabrieftreatmentpatternreviewfromaradiationoncologistspointofview
AT kihoonsung caseofprimarybreastdiffuselargebcelllymphomatreatedwithchemotherapyfollowedbyelectivefieldradiationtherapyabrieftreatmentpatternreviewfromaradiationoncologistspointofview
AT sohyunahn caseofprimarybreastdiffuselargebcelllymphomatreatedwithchemotherapyfollowedbyelectivefieldradiationtherapyabrieftreatmentpatternreviewfromaradiationoncologistspointofview
AT jinhochoi caseofprimarybreastdiffuselargebcelllymphomatreatedwithchemotherapyfollowedbyelectivefieldradiationtherapyabrieftreatmentpatternreviewfromaradiationoncologistspointofview
AT seokholee caseofprimarybreastdiffuselargebcelllymphomatreatedwithchemotherapyfollowedbyelectivefieldradiationtherapyabrieftreatmentpatternreviewfromaradiationoncologistspointofview
AT jaehoonlee caseofprimarybreastdiffuselargebcelllymphomatreatedwithchemotherapyfollowedbyelectivefieldradiationtherapyabrieftreatmentpatternreviewfromaradiationoncologistspointofview
AT junshikhong caseofprimarybreastdiffuselargebcelllymphomatreatedwithchemotherapyfollowedbyelectivefieldradiationtherapyabrieftreatmentpatternreviewfromaradiationoncologistspointofview
AT sanghuipark caseofprimarybreastdiffuselargebcelllymphomatreatedwithchemotherapyfollowedbyelectivefieldradiationtherapyabrieftreatmentpatternreviewfromaradiationoncologistspointofview