Treatment Approaches for Bronchopulmonary Infection in Myasthenia Gravis Patients

Nineteen patients with bronchopulmonary infection and myasthenia gravis were enrolled in the study. The microbiological analysis of the specimens of phlegm and bronchial secretion revealed both grampositive and gramnegative bacteria. All the isolates were susceptible to the antibiotic used (cefopera...

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Main Authors: V. I. Sokolova, A. G. Sanadze, D. A. Sychev, M. B. Babarina, D. A. Zaykov
Format: Article
Language:Russian
Published: LLC "Publishing House OKI" 2020-05-01
Series:Антибиотики и Химиотерапия
Subjects:
Online Access:https://www.antibiotics-chemotherapy.ru/jour/article/view/527
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author V. I. Sokolova
A. G. Sanadze
D. A. Sychev
M. B. Babarina
D. A. Zaykov
author_facet V. I. Sokolova
A. G. Sanadze
D. A. Sychev
M. B. Babarina
D. A. Zaykov
author_sort V. I. Sokolova
collection DOAJ
description Nineteen patients with bronchopulmonary infection and myasthenia gravis were enrolled in the study. The microbiological analysis of the specimens of phlegm and bronchial secretion revealed both grampositive and gramnegative bacteria. All the isolates were susceptible to the antibiotic used (cefoperazone/sulbactam). Intravenous immunoglobulins (IvIgs) were used to increase the treatment efficacy, to opsonize the infection foci and to decrease the hospitalization terms. The antibiotic therapy and simultaneous use of intravenous immunoglobulins provided higher clinical efficacy in 16 out of 19 patients (84.2%).
format Article
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institution Kabale University
issn 0235-2990
language Russian
publishDate 2020-05-01
publisher LLC "Publishing House OKI"
record_format Article
series Антибиотики и Химиотерапия
spelling doaj-art-e3a84a69fdc64d3ebaeaceff38ef36752025-08-20T03:59:08ZrusLLC "Publishing House OKI"Антибиотики и Химиотерапия0235-29902020-05-01591-22023526Treatment Approaches for Bronchopulmonary Infection in Myasthenia Gravis PatientsV. I. Sokolova0A. G. Sanadze1D. A. Sychev2M. B. Babarina3D. A. Zaykov4Russian Medical Academy of Postgraduate Education, MoscowRussian Medical Academy of Postgraduate Education, MoscowRussian Medical Academy of Postgraduate Education, MoscowRussian Medical Academy of Postgraduate Education, MoscowRussian Medical Academy of Postgraduate Education, MoscowNineteen patients with bronchopulmonary infection and myasthenia gravis were enrolled in the study. The microbiological analysis of the specimens of phlegm and bronchial secretion revealed both grampositive and gramnegative bacteria. All the isolates were susceptible to the antibiotic used (cefoperazone/sulbactam). Intravenous immunoglobulins (IvIgs) were used to increase the treatment efficacy, to opsonize the infection foci and to decrease the hospitalization terms. The antibiotic therapy and simultaneous use of intravenous immunoglobulins provided higher clinical efficacy in 16 out of 19 patients (84.2%).https://www.antibiotics-chemotherapy.ru/jour/article/view/527myasthenia gravisneuromuscular conductivitypyridostigminemethylprednisoloneimmunitybronchopulmonary infectionmicrobiological profilecefoperazone/sulbactamintravenous immunoglobulins
spellingShingle V. I. Sokolova
A. G. Sanadze
D. A. Sychev
M. B. Babarina
D. A. Zaykov
Treatment Approaches for Bronchopulmonary Infection in Myasthenia Gravis Patients
Антибиотики и Химиотерапия
myasthenia gravis
neuromuscular conductivity
pyridostigmine
methylprednisolone
immunity
bronchopulmonary infection
microbiological profile
cefoperazone/sulbactam
intravenous immunoglobulins
title Treatment Approaches for Bronchopulmonary Infection in Myasthenia Gravis Patients
title_full Treatment Approaches for Bronchopulmonary Infection in Myasthenia Gravis Patients
title_fullStr Treatment Approaches for Bronchopulmonary Infection in Myasthenia Gravis Patients
title_full_unstemmed Treatment Approaches for Bronchopulmonary Infection in Myasthenia Gravis Patients
title_short Treatment Approaches for Bronchopulmonary Infection in Myasthenia Gravis Patients
title_sort treatment approaches for bronchopulmonary infection in myasthenia gravis patients
topic myasthenia gravis
neuromuscular conductivity
pyridostigmine
methylprednisolone
immunity
bronchopulmonary infection
microbiological profile
cefoperazone/sulbactam
intravenous immunoglobulins
url https://www.antibiotics-chemotherapy.ru/jour/article/view/527
work_keys_str_mv AT visokolova treatmentapproachesforbronchopulmonaryinfectioninmyastheniagravispatients
AT agsanadze treatmentapproachesforbronchopulmonaryinfectioninmyastheniagravispatients
AT dasychev treatmentapproachesforbronchopulmonaryinfectioninmyastheniagravispatients
AT mbbabarina treatmentapproachesforbronchopulmonaryinfectioninmyastheniagravispatients
AT dazaykov treatmentapproachesforbronchopulmonaryinfectioninmyastheniagravispatients