Causal associations between gut microbiota, metabolites, and idiopathic normal pressure hydrocephalus: a two‑sample Mendelian randomization study

Causal associations between gut microbiota, metabolites, and idiopathic normal pressure hydrocephalus: a two‑sample Mendelian randomization study

Abstract Background Implying connections with gut microbiome and serum metabolites, idiopathic normal pressure hydrocephalus (INPH) emerges as a prevalent neuropsychiatric condition in the elderly. Our objective was to systematically evaluate the potential causality between gut microbiome, derived m...

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Bibliographic Details
Main Authors: Wencai Wang, Menghao Liu, Zun Wang, Luyao Ma, Yongqiang Zhao, Wei Ye, Xianfeng Li
Format: Article
Language:English
Published: BMC 2025-06-01
Series:BMC Neurology
Subjects:
INPH
Gut microbiota
Serum metabolites
GWAS
Mendelian randomization
Online Access:https://doi.org/10.1186/s12883-025-04187-4
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