Constituent Analysis and Quality Evaluation of Epimedii Folium from Different Species
Epimedii Folium (EF) is a commonly used traditional Chinese drug that includes many species. In Chinese Pharmacopoeia (2020 edition), EF includes Epimedium brevicornu Maxim, E. Sagittatum (Sieb. et Zucc) Maxim, E. pubescens Maxim, E. koreanum Nakai, and Epimedium Wushanense T.S. Ying. It has been re...
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| Format: | Article |
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Wiley
2023-01-01
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| Series: | Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2023/4221158 |
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| author | Jia Xue Haijie Chen Yongyi Zhou Jiahuan Yuan Zhichen Cai Nan Wu Cuihua Chen Lisi Zou Shengxin Yin Wei Yang Xunhong Liu Jianming Cheng Yihao Sun |
| author_facet | Jia Xue Haijie Chen Yongyi Zhou Jiahuan Yuan Zhichen Cai Nan Wu Cuihua Chen Lisi Zou Shengxin Yin Wei Yang Xunhong Liu Jianming Cheng Yihao Sun |
| author_sort | Jia Xue |
| collection | DOAJ |
| description | Epimedii Folium (EF) is a commonly used traditional Chinese drug that includes many species. In Chinese Pharmacopoeia (2020 edition), EF includes Epimedium brevicornu Maxim, E. Sagittatum (Sieb. et Zucc) Maxim, E. pubescens Maxim, E. koreanum Nakai, and Epimedium Wushanense T.S. Ying. It has been reported that the active constituents in EF are different, resulting in the uneven quality of commercial medicinal materials. To explore the specific differences and make a comprehensive quality evaluation of EF, we established an analytical method to simultaneously detect 45 constituents including 23 flavonoids, 4 phenolic acids, 12 amino acids, 5 nucleosides, and 1 alkaloid in 5 species of EF, based on ultrafast performance liquid chromatography coupled with triple quadrupole-linear ion trap mass spectrometry (UFLC-QTRAP-MS/MS). In addition, orthogonal partial least squares discriminant analysis (OPLS-DA), analysis of variance (ANOVA), and grey correlation analysis (GRA) were used to discriminate and evaluate different species of samples. The results showed that EF could be divided into three categories and EBM was superior to the other four species. This study provides data basis for the comprehensive evaluation and a new perspective on the quality control of EF from different species. |
| format | Article |
| id | doaj-art-e3a69a6d345d4cc78b502ecb4a548fb2 |
| institution | OA Journals |
| issn | 2090-9071 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Chemistry |
| spelling | doaj-art-e3a69a6d345d4cc78b502ecb4a548fb22025-08-20T02:21:24ZengWileyJournal of Chemistry2090-90712023-01-01202310.1155/2023/4221158Constituent Analysis and Quality Evaluation of Epimedii Folium from Different SpeciesJia Xue0Haijie Chen1Yongyi Zhou2Jiahuan Yuan3Zhichen Cai4Nan Wu5Cuihua Chen6Lisi Zou7Shengxin Yin8Wei Yang9Xunhong Liu10Jianming Cheng11Yihao Sun12College of PharmacyCollege of PharmacyCollege of PharmacyCollege of PharmacyCollege of PharmacyCollege of PharmacyCollege of PharmacyCollege of PharmacyCollege of PharmacyCollege of PharmacyCollege of PharmacyCollege of PharmacyCollege of PharmacyEpimedii Folium (EF) is a commonly used traditional Chinese drug that includes many species. In Chinese Pharmacopoeia (2020 edition), EF includes Epimedium brevicornu Maxim, E. Sagittatum (Sieb. et Zucc) Maxim, E. pubescens Maxim, E. koreanum Nakai, and Epimedium Wushanense T.S. Ying. It has been reported that the active constituents in EF are different, resulting in the uneven quality of commercial medicinal materials. To explore the specific differences and make a comprehensive quality evaluation of EF, we established an analytical method to simultaneously detect 45 constituents including 23 flavonoids, 4 phenolic acids, 12 amino acids, 5 nucleosides, and 1 alkaloid in 5 species of EF, based on ultrafast performance liquid chromatography coupled with triple quadrupole-linear ion trap mass spectrometry (UFLC-QTRAP-MS/MS). In addition, orthogonal partial least squares discriminant analysis (OPLS-DA), analysis of variance (ANOVA), and grey correlation analysis (GRA) were used to discriminate and evaluate different species of samples. The results showed that EF could be divided into three categories and EBM was superior to the other four species. This study provides data basis for the comprehensive evaluation and a new perspective on the quality control of EF from different species.http://dx.doi.org/10.1155/2023/4221158 |
| spellingShingle | Jia Xue Haijie Chen Yongyi Zhou Jiahuan Yuan Zhichen Cai Nan Wu Cuihua Chen Lisi Zou Shengxin Yin Wei Yang Xunhong Liu Jianming Cheng Yihao Sun Constituent Analysis and Quality Evaluation of Epimedii Folium from Different Species Journal of Chemistry |
| title | Constituent Analysis and Quality Evaluation of Epimedii Folium from Different Species |
| title_full | Constituent Analysis and Quality Evaluation of Epimedii Folium from Different Species |
| title_fullStr | Constituent Analysis and Quality Evaluation of Epimedii Folium from Different Species |
| title_full_unstemmed | Constituent Analysis and Quality Evaluation of Epimedii Folium from Different Species |
| title_short | Constituent Analysis and Quality Evaluation of Epimedii Folium from Different Species |
| title_sort | constituent analysis and quality evaluation of epimedii folium from different species |
| url | http://dx.doi.org/10.1155/2023/4221158 |
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