ER-induced PERK/TFEB cascade sequentially modulates mitochondrial dynamics during cranial suture expansion

Abstract The effectiveness of cranial suture expansion therapy hinges on the timely and adequate regeneration of bone tissue in response to mechanical stimuli. To optimize clinical outcomes and prevent post-expansion relapse, we delved into the underlying mechanisms governing bone remodeling during...

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Bibliographic Details
Main Authors: Jingyi Cai, Ziyang Min, Chaoyuan Li, Zhihe Zhao, Jun Liu, Dian Jing
Format: Article
Language:English
Published: Nature Publishing Group 2025-06-01
Series:Bone Research
Online Access:https://doi.org/10.1038/s41413-025-00427-y
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