Temporal analysis of gestational and congenital syphilis indicators in Brazil: toward the elimination of vertical transmission by 2030?

ABSTRACT Objective: To analyze, at national and regional levels, the trend of proxy indicators for the progress toward the elimination of the vertical transmission of syphilis in Brazil. Methods: This is an ecological study that assessed the annual percent change (APC) of indicators related to ges...

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Main Authors: Gabriel Pavinati, Lucas Vinícius de Lima, Marjorie Fairuzy Stolarz, Melissa Ferrari Gomes, Sidnei Nathan Soares Turquino, Gabriela Tavares Magnabosco
Format: Article
Language:English
Published: Associação Brasileira de Pós-Graduação em Saúde Coletiva 2025-06-01
Series:Revista Brasileira de Epidemiologia
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-790X2025000100902&lng=en&tlng=en
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author Gabriel Pavinati
Lucas Vinícius de Lima
Marjorie Fairuzy Stolarz
Melissa Ferrari Gomes
Sidnei Nathan Soares Turquino
Gabriela Tavares Magnabosco
author_facet Gabriel Pavinati
Lucas Vinícius de Lima
Marjorie Fairuzy Stolarz
Melissa Ferrari Gomes
Sidnei Nathan Soares Turquino
Gabriela Tavares Magnabosco
author_sort Gabriel Pavinati
collection DOAJ
description ABSTRACT Objective: To analyze, at national and regional levels, the trend of proxy indicators for the progress toward the elimination of the vertical transmission of syphilis in Brazil. Methods: This is an ecological study that assessed the annual percent change (APC) of indicators related to gestational and congenital syphilis. Results: An APC of 11.15% was observed in the detection rate of gestational syphilis (95% confidence interval — 95%CI 2.78–23.19), with stability in congenital syphilis across all regions. There was a reduction of prenatal care coverage among pregnant women with syphilis (APC=-7.34%; 95%CI -10.15; -5.33), and also a decrease in late diagnosis of the infection (APC=-10.77%; 95%CI -14.29; -8.79). Conclusions: We evidenced challenges in achieving the 2030 elimination targets, highlighting the need for adjustments in current public policies on syphilis prevention and control.
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language English
publishDate 2025-06-01
publisher Associação Brasileira de Pós-Graduação em Saúde Coletiva
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series Revista Brasileira de Epidemiologia
spelling doaj-art-e39a5a9c70154dd393bbca0bbd7594642025-08-20T02:05:24ZengAssociação Brasileira de Pós-Graduação em Saúde ColetivaRevista Brasileira de Epidemiologia1980-54972025-06-012810.1590/1980-549720250028Temporal analysis of gestational and congenital syphilis indicators in Brazil: toward the elimination of vertical transmission by 2030?Gabriel Pavinatihttps://orcid.org/0000-0002-0289-8219Lucas Vinícius de Limahttps://orcid.org/0000-0002-9582-9641Marjorie Fairuzy Stolarzhttps://orcid.org/0000-0002-8545-9886Melissa Ferrari Gomeshttps://orcid.org/0000-0003-1705-7030Sidnei Nathan Soares Turquinohttps://orcid.org/0009-0002-5361-0251Gabriela Tavares Magnaboscohttps://orcid.org/0000-0003-3318-6748ABSTRACT Objective: To analyze, at national and regional levels, the trend of proxy indicators for the progress toward the elimination of the vertical transmission of syphilis in Brazil. Methods: This is an ecological study that assessed the annual percent change (APC) of indicators related to gestational and congenital syphilis. Results: An APC of 11.15% was observed in the detection rate of gestational syphilis (95% confidence interval — 95%CI 2.78–23.19), with stability in congenital syphilis across all regions. There was a reduction of prenatal care coverage among pregnant women with syphilis (APC=-7.34%; 95%CI -10.15; -5.33), and also a decrease in late diagnosis of the infection (APC=-10.77%; 95%CI -14.29; -8.79). Conclusions: We evidenced challenges in achieving the 2030 elimination targets, highlighting the need for adjustments in current public policies on syphilis prevention and control.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-790X2025000100902&lng=en&tlng=enSyphilisSyphilis, congenitalInfectious disease transmission, verticalSustainable developmentTime series studies
spellingShingle Gabriel Pavinati
Lucas Vinícius de Lima
Marjorie Fairuzy Stolarz
Melissa Ferrari Gomes
Sidnei Nathan Soares Turquino
Gabriela Tavares Magnabosco
Temporal analysis of gestational and congenital syphilis indicators in Brazil: toward the elimination of vertical transmission by 2030?
Revista Brasileira de Epidemiologia
Syphilis
Syphilis, congenital
Infectious disease transmission, vertical
Sustainable development
Time series studies
title Temporal analysis of gestational and congenital syphilis indicators in Brazil: toward the elimination of vertical transmission by 2030?
title_full Temporal analysis of gestational and congenital syphilis indicators in Brazil: toward the elimination of vertical transmission by 2030?
title_fullStr Temporal analysis of gestational and congenital syphilis indicators in Brazil: toward the elimination of vertical transmission by 2030?
title_full_unstemmed Temporal analysis of gestational and congenital syphilis indicators in Brazil: toward the elimination of vertical transmission by 2030?
title_short Temporal analysis of gestational and congenital syphilis indicators in Brazil: toward the elimination of vertical transmission by 2030?
title_sort temporal analysis of gestational and congenital syphilis indicators in brazil toward the elimination of vertical transmission by 2030
topic Syphilis
Syphilis, congenital
Infectious disease transmission, vertical
Sustainable development
Time series studies
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-790X2025000100902&lng=en&tlng=en
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