Why this is not multiple sclerosis: a case based approach

Objective To present a case series of patients previously diagnosed as multiple sclerosis (MS) which were later confirmed as an alternative diagnosis, and describe the clinical and paraclinical signs that led to this change.Method Nine patients are described. We reviewed the patient’s clinical chart...

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Main Authors: Zaira Fernanda Martinho Nicolau, Enedina Maria Lobato de Oliveira, Denis Bernardi Bichuetti
Format: Article
Language:English
Published: Thieme Revinter Publicações 2015-01-01
Series:Arquivos de Neuro-Psiquiatria
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015005050163&lng=en&tlng=en
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author Zaira Fernanda Martinho Nicolau
Enedina Maria Lobato de Oliveira
Denis Bernardi Bichuetti
author_facet Zaira Fernanda Martinho Nicolau
Enedina Maria Lobato de Oliveira
Denis Bernardi Bichuetti
author_sort Zaira Fernanda Martinho Nicolau
collection DOAJ
description Objective To present a case series of patients previously diagnosed as multiple sclerosis (MS) which were later confirmed as an alternative diagnosis, and describe the clinical and paraclinical signs that led to this change.Method Nine patients are described. We reviewed the patient’s clinical chart, magnetic resonance images (MRI) and cerebrospinal fluid.Results There was a mean of three typical symptoms of MS and four clinical red flags per patient. MRI red flags were found in 88,9% of all referrals, with a mean of 3 encountered per patient.Conclusion We identified that, not only the misdiagnosed patients did not fulfill MS diagnosis criteria, but also how the described red flags are a useful tool in the differentiation of MS from other diseases. This data is important for guiding future diagnosis, especially for general clinicians and neurologists, which directly interfere with the patient’s management, treatment, prognosis and quality of life.
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institution Kabale University
issn 1678-4227
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publishDate 2015-01-01
publisher Thieme Revinter Publicações
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series Arquivos de Neuro-Psiquiatria
spelling doaj-art-e398e357f37e4d239696d20022d2fad92025-08-20T03:26:31ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-42272015-01-0100010.1590/0004-282X20150163S0004-282X2015005050163Why this is not multiple sclerosis: a case based approachZaira Fernanda Martinho NicolauEnedina Maria Lobato de OliveiraDenis Bernardi BichuettiObjective To present a case series of patients previously diagnosed as multiple sclerosis (MS) which were later confirmed as an alternative diagnosis, and describe the clinical and paraclinical signs that led to this change.Method Nine patients are described. We reviewed the patient’s clinical chart, magnetic resonance images (MRI) and cerebrospinal fluid.Results There was a mean of three typical symptoms of MS and four clinical red flags per patient. MRI red flags were found in 88,9% of all referrals, with a mean of 3 encountered per patient.Conclusion We identified that, not only the misdiagnosed patients did not fulfill MS diagnosis criteria, but also how the described red flags are a useful tool in the differentiation of MS from other diseases. This data is important for guiding future diagnosis, especially for general clinicians and neurologists, which directly interfere with the patient’s management, treatment, prognosis and quality of life.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015005050163&lng=en&tlng=enesclerose múltipladiagnósticoclínicoressonância magnética
spellingShingle Zaira Fernanda Martinho Nicolau
Enedina Maria Lobato de Oliveira
Denis Bernardi Bichuetti
Why this is not multiple sclerosis: a case based approach
Arquivos de Neuro-Psiquiatria
esclerose múltipla
diagnóstico
clínico
ressonância magnética
title Why this is not multiple sclerosis: a case based approach
title_full Why this is not multiple sclerosis: a case based approach
title_fullStr Why this is not multiple sclerosis: a case based approach
title_full_unstemmed Why this is not multiple sclerosis: a case based approach
title_short Why this is not multiple sclerosis: a case based approach
title_sort why this is not multiple sclerosis a case based approach
topic esclerose múltipla
diagnóstico
clínico
ressonância magnética
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015005050163&lng=en&tlng=en
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AT enedinamarialobatodeoliveira whythisisnotmultiplesclerosisacasebasedapproach
AT denisbernardibichuetti whythisisnotmultiplesclerosisacasebasedapproach