D-pinitol modulates the anti-emetic effects of aprepitant, domperidone, and ondansetron in chicks

D-pinitol modulates the anti-emetic effects of aprepitant, domperidone, and ondansetron in chicks

Naturally occurring substance, D-pinitol (DPL) belongs to the significant inositol family has numerous pharmacological activity. In this study we evaluated the anti-emetic effect as well as modulation activities of DPL on the recent market drugs aprepitant (APR), domperidone (DOM), hyoscine butyl br...

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Main Authors: Md. Elit Rahman, Md. Anisur Rahman, Salehin Sheikh, Md. Jannatul Islam Polash, Sozoni Khatun, Mst. Sonia Akter Bristi, Md. Showkoth Akbor, Mst. Farjanamul Haque, Mehedi Hasan Bappi, Tohidul Islam Tanim, Siddique Akber Ansari, Irfan Aamer Ansari, Elaine Cristina Pereira Lucetti, Carolina Bandeira Domiciano, Henrique D.M. Coutinho, Muhammad Torequl Islam
Format: Article
Language:English
Published: Elsevier 2025-12-01
Series:Pharmaceutical Science Advances
Subjects:
Anti-emetic
Emesis
D-pinitol
Molecular docking
Pharmacokinetics
Toxicity
Online Access:http://www.sciencedirect.com/science/article/pii/S277321692500011X
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